Faculty of Medicine
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Item type:Publication, Effects of age and gender on concentration of lipid parameters and glucose in elderly patients(Македонско лекарско друштво = Macedonian medical association, 2024-12); ; Objective: Lipids have significant biochemical functions, but their excess can also be a high-risk factor for cardiovascular disease (CVD). Glucose levels, diabetes and as well aging seriously contribute in increasing the prevalence of CVD. The main aim of the study is to analyze the correlation between age and gender with the concentration of lipid parameters and glucose in elderly patients. Material and methods: A total of 50 patients selected from the Medical Biochemistry Laboratory in Bitola were included in the study. Triglycerides (TG), total cholesterol (TC), and fasting blood glucose levels were measured quantitatively using standard methods. Results were evaluated to identify a potential association between age, gender and blood glucose as well as lipid parameters. Results: The selected group consisted in 50 patients, of whom 24 (48%) males and 26 (52%) females. The age ranged between 55 and 83 years old, with a median age of 72. The median value of each was as follows: triglycerides 1,614 mmol/l (ranging 0.5-5.9 mmol/l), cholesterol 5.464 mmol/l (ranging 3.3-7.7 mmol/l) and glucose 6.85 mmol/l (ranging 4.8-13.4 mmol/l). We compared the parameters regarding gender and age. No correlation was found when comparing the age and value of triglycerides or cholesterol, while regarding the glucose status, Pearson`s correlation was not statistically significant (p=0.06). Chi-squared test regarding the gender and the normal or results above the reference value showed a statistical significance regarding the triglycerides status and gender (p=0.011). There was no statistical significance regarding gender and results of cholesterol and glucose levels. Conclusion: Our results show a plausible correlation between these parameters and the gender of the patients. Considering the increasing age, decreasing levels of hormones especially estrogen in women, factors such as lifestyle and habits, regular checkups are required. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, OBESITY AND AGE AS A RISK FACTORS FOR URINARY INCONTINENCE IN WOMEN(Institute of Knowledge Management, 2021-10) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, COPD IN A SAMPLE OF GENERAL ADULT POPULATION FROM THE SKOPJE REGION(University Ss. Cyril and Methodius in Skopje, 2022); ; ; ; Atanasovska, AnetaIntroduction. Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity, disability and mortality in the last decades worldwide. Aim of the study. To determine the COPD prevalence in a sample of general adult population from the Skopje region and its distribution by sex, age, smoking status, working status, family history of chronic bronchitis/asthma, and mode of household heating and cooking. Methods. A cross-sectional study (prevalence study) including 2,348 participants (1,239 males and 1,109 females, aged 18 to 86 years) from the Skopje region was performed at the Institute for Occupational Health of RN Macedonia, Skopje, in the period 2018-2021. The study protocol included completion of a questionnaire and spirometric measurements (pre and post-bronchodilator spirometry). COPD was defined by spirometric finding of persistent airflow limitation in symptomatic study subjects. Results. COPD prevalence in the whole study sample was 4.6%, being non-significantly higher in men (5.1%) than in women (4.1%). Fourfold higher prevalence of COPD was registered in the study subjects aged over 45 years as compared to the younger ones (6.7% vs. 1.6%; P = 0.000). COPD prevalence was significantly higher in active smokers as compared to non-smoking study subjects (9.4% vs. 1.9%; P = 0.000). In regard to working status, COPD prevalence among active workers was 3.9%, in the group of retired persons 8.7%, while in the group of students there was not a single subject with COPD. In addition, COPD prevalence in the workers occupationally exposed to noxious particles or gases was significantly higher than in unexposed workers (4.7% vs. 2.4%; P = 0.021). There was no statistically significant difference in the COPD prevalence between study subjects with positive and negative family history of asthma/chronic bronchitis (4.8% vs. 4.5%), as well as between study subjects who used biomass fuels for heating and cooking (6.2%) and those who did not use traditional fuels for household needs (4.0%). Conclusion. Our findings have indicated the age, active smoking and occupational exposures to noxious particles or gases as the factors significantly related to COPD prevalence in the examined sample of general adult population from the Skopje region. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ASSOCIATION BETWEEN FIRST TRIMESTER OBESITY AND SOME MATERNAL CHARACTERISTICS(Македонско лекарско друштво = Macedonian Medical Association, 2020); ;