Faculty of Medicine
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Item type:Publication, PREVALENCE OF PSYCHOSIS IN NORTH MACEDONIA FOR THE PERIOD FROM 2020 TO 2023(Macedonian Medical Association, 2025-09); The aim of the study was to estimate the prevalence of psychosis in the Republic of North Macedonia (RNM) for the period 2020-2023. Data from the Psychosis Registry of the Institute of Public Health - Skopje, as well as reports from the Public Health Centers in the Republic of North Macedonia, were used. A descriptive-analytical method was used to analyze and present the results. In 2020, the overall rate of psychosis cases was 134.88 per 100,000 population. In 2023, the rate doubled to 299.3 per 100,000 population. In 2023, the rate doubled to 299.3 per 100,000 inhabitants. The largest number of cases for the entire period was diagnosed in the population aged 45-54 years (3935). There are also regional differences, with the most cases documented in the Skopje (1462) and Pelagonia regions (1287). Conclusion: The trend of people suffering from psychosis in our country is continuously increasing. The most affected by this disease are males and the adult population. The results demonstrate the importance of early detection and targeted interventions to address the prevalence of psychosis across different population groups. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PREVALENCE AND IDENTIFICATION OF POTENTIAL PREDICTORS ASSOCIATED WITH GESTATIONAL DIABETES MELLITUS IM MACEDONIA(Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2025-03-01); ; Ninova, AgavniIntroduction: Peripheral nerve blocks have an increasingly important role as an anesthetic technique for surgical anesthesia, postoperative analgesia, and fast discharge of patients after surgery involving the upper or lower extremities, alone or in combination with spinal or general anesthesia. Ultrasound guidance has become the most popular for performance of peripheral nerve blocks. Methods: In our retrospective study, we included all patients that were admitted in our hospital for orthopedic procedures on lower and upper extremities who received peripheral nerve block, alone or in combination with spinal or general anesthesia in the last 5 years. Ultrasound guidance was used and local anesthetic Bupivacaine 0.5%. Dexamethasone 4 mg was given intravenously as an adjuvant to peripheral nerve blocks. Results: The total number of patients included in our study was 300, the total number of performed peripheral nerve blocks was 302. 144 (48%) patients were male and 156 (52%) – female. The type of performed blocks was: 164 (54%) femoral, adductor canal blocks 22 (7.28%), 26 supraclavicular (8.60%), 77 interscalene (25.49%), 9 axillar (2.98%), 2 popliteal (0.66%), 1 iPACK and 1 TAP block (0.33%). Peripheral nerve blocks were combined with general or spinal anesthesia or performed as a sole technique for intraoperative analgesia in 17 patients (5.67%). Discussion: In our hospital we performed ultrasound guided peripheral nerve blocks last years in combination with a general, spinal anesthesia or as a sole technic for intraoperative and postoperative analgesia. Our patients were very satisfied with good postoperative pain control, and no serious complications were observed. Conclusion: Ultrasound guided peripheral nerve blocks are good choice for intraoperative anesthesia and postoperative analgesia, especially in older patients and patients with a lot of comorbidities. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Unveiling the neuropathology tumour landscape: 10-year statistical analysis with global comparison – Single centre experience(Macedonian Academy of Sciences and Arts, 2023-12); ; ; ; Introduction: Central nervous system (CNS) tumours represent a significant public health issue worldwide, and their incidence and distribution vary across different populations. Although studies on CNS tumours have been conducted in various countries, there is a lack of information regarding their patterns in Macedonia. Therefore, this study is aimed at investigating the distribution, histopathological types and subtypes and demographic features of CNS tumours in our country. Materials and Methods: A cross sectional study was conducted using the electronic database of the Institute of Pathology – Medical Faculty, University “Ss. Cyril and Methodius” in Skopje which contains data from 3286 received and analysed surgical specimens, mainly from the University Clinic of Neurosurgery in Skopje, and a smaller number of surgical specimens from the University Surgical Centre “St. Naum Ohridski” in Skopje between 2012 and 2022. The collected and analysed data includes patient age, sex and histopathological types and subtypes of the tumours. Results: The majority of CNS tumours were diagnosed in adults aged between 50-70, with a male to female ratio of 1.5:1. The most common location of the tumours was the cerebrum, followed by the pituitary gland and cerebellum. The most frequent histological groups were gliomas, with glioblastoma as the most common diagnosis, followed by meningiomas. Conclusion: Following a detailed and thorough review of the CNS tumours in our study, we can conclude that the R. of Macedonia follows global statistics and trends regarding brain tumours. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Assosiation of COVID-19 Infection and Acute Mesenteric Ischemia(The First Faculty of Medicine of Charles University - Karolinum press, 2023-12); - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Prevalence of congenital hypothyroidism in North Macedonia: data from a newborn screening program conducted for twenty years(Turkish National Pediatric Society, 2023); ; ; Meceska Jovcevska, JasminaBackground. Congenital hypothyroidism (CH) is a common endocrine disorder that can be treated if timely detected by newborn screening, optimizing the developmental outcome in affected children. In the present study, we analyze the data of the national newborn thyroid screening program in North Macedonia collected over twenty years, including the CH prevalence as well as its geographical and ethnic variations. Methods. The thyroid-stimulating hormone (TSH) was measured on a filter paper blood spot sample using the DELFIA fluoroimmunometric assay. A TSH value of 15 mIU/L whole blood was used as the cutoff point until 2010 and 10 mIU/L thereafter. Results. Out of 377,508 screened live births, a total of 226 newborns with primary CH were detected, providing an overall prevalence of 6.0 per 10,000. Lowering the TSH cutoff led to an apparently increased prevalence of the transient CH, from 0.2 to 2.4 per 10,000 live births (p<0.0001) with an impact on the overall prevalence of primary CH (from 4.0 to 7.1 per 10,000, p=0.0001). Taking ethnicity into account, the significantly highest primary CH prevalence of 11.3 per 10,000 live births was observed among the Roma neonates, with a predominance of permanent CH (75.5%). There were also regional differences in the prevalence of primary CH. The highest primary CH prevalence of 11.7 per 10,000 live births was observed in the Vardar region, together with the highest regional prevalence of the transient CH (3.2 per 10,000). The highest prevalence of permanent CH was observed in the Pelagonia region (6.6 per 10,000) where the largest percentage of the Roma population lives. Conclusions. The overall CH prevalence is high in North Macedonia, with substantial ethnic and geographical variations. Further analysis to elucidate the causes for the significant variations in the CH prevalence including environmental factors is warranted - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Myocardial Infarction in Systemic Lupus Erythematosus - the Sex Specific Risk Profile(Bentham Science Publishers Ltd., 2020-12-09); ; ; Accelerated atherosclerosis is widely present in patients with systemic lupus erythematosus. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three(Elsevier BV, 2009-12)