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Language: search.filters.language.EnglishSubject: search.filters.subject.optical coherence tomography

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    High Risk Percutaneous Coronary Intervention of Left Main Bifurcation Stenosis in a Peritoneal Dialysis Patient
    (Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2021-10-26)
    Bushljetikj, Oliver
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    Dezulovic, Frosina Arnaudova
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    Complex coronary artery disease is the leading cause of death in patients with end-stage renal disease. We report a case of a patient on peritoneal dialysis, preloaded with Prasugrel and acetylsalicylic acid as а potent dual antiplatelet therapy (DAPT). The patient underwent a high-risk percutaneous coronary intervention (PCI) due to bifurcation stenosis of the left main stem branch. A "double kiss crush" bifurcation stenting technique was performed. This case provides additional data about the treatment of this group of patients, a group that is often excluded from randomized control trials, but is frequently encountered in cardiovascular practice. Furthermore, it helps to advance PCI treatment along with exploring the safety of potent DAPT in a group that is susceptible to both ischemia and bleeding, thus presenting a great challenge in the decision for treatment.
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    Mutation of ABCA4 gene as a cause of autosomal recessive form of Stargardt disease – case report
    (Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2024-12)
    Spirkovska Mangeroska, Angelka
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    Pandilov, Stefan
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    Rushiti, Muhamedin
    Stargardt disease is the most common type of juvenile macular dystrophy. It is inherited autosomal recessively, although autosomal dominant forms have also been described. It affects both sexes equally, without racial predisposition. Patients experience a progressive deterioration of the macular region and loss of central vision, leading to legal blindness in the majority of affected individuals.In this paper, we describe the case of an 11-year-old boy who presented for an ophthalmological evaluation due to a progressive decrease in visual acuity. The fundoscopic examination supplemented with imaging ophthalmological methods were sufficient to establish a working diagnosis of Stargardt disease. The diagnosis was confirmed by genetic testing, a mutation of the ABCA4 gene, which is associated with this dystrophy. The importance of this case report is that it is one of the first documented cases of Stargardt disease with ABCA4 mutation in Macedonia
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    Evaluation of corneal changes in chemical burns with anterior segment optical coherence tomography
    (South-East European Ophthalmological Society, 2015-12)
    M. Antova Velevska
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    Aims: Chemical injuries of the anterior segment of the eye are a common problem and may cause a serious damage to the eye. Proper management in the acute setting, as well as follow up examination and evaluation is crucial in limiting adverse effects of ocular tissue damage. Purpose: To present the application of anterior segment optical coherence tomography (AS-OCT) evaluation of the corneal changes in patients with chemical injuries. Patients and Methods: Retrospective non comparative series of 17 eyes in 14 patients who were evaluated and treated at the University Eye Clinic Skopje. The Topcon SL Scan 1 and color photography were used in each injured eye, OCT-AS scanning was performed at the first examination and the follow up examination. All scans were carried out with scanning beam passing through the centre at specific meridians. Quantitative parameters of the corneal thickness were also investigated. Color photography was correlated with OCT findings. Results: A characteristic AS-OCT images of the cornea ex vivo is shown. The epithelial and endothelial layers, the stromal fibers are distinguished. Also OCT images of the corneal tissue damage caused by chemical interaction are presented. Summary: We showed that the AS-OCT is capable of imaging and evaluation of chemical injuries in real time. It was demonstrated that AS-OCT is sensitive to the changes in the structural properties of the cornea as a result of the chemical damage.