Faculty of Medicine
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Item type:Publication, IMPACT OF BUPRENORPHINE THERAPY ON THE NORMALIZATION OF SEXUAL FUNCTION AND STATES OF ANXIETY(Institute of Management & Knowledge, 2025-05); Abstract: According to certain, studies, chronic opioid use has a major impact on the function of the hypothalamicpituitary-adrenal axis. Hypogonadism occurs in more than half of male opioid users and elevated cortisol levels in approximately one-fifth of addicts. Buprenorphine as a kappa opioid antagonist reduced release of adrenocorticotropic hormone and in these way was reducing anxiety and depression in heroin addicts. The AIM of our research was to determinate the impact of buprenorphine therapy on sexual function and anxiety. Materials and methods: The cross-sectional study included 19 male and 1 female patients on buprenorphine therapy aged between 25-51years with a diagnosis of F11.22. The patients were evaluated in the Day hospital for treatment of drug abuse, department of Psychiatric Hospital Skopje. Sociodemographic characteristics (age, marital status, years of education, employment) of patients were determined using a questionnaire specially designed for the study. The anxiety state of the patients was determined using the Hamilton Anxiety Rating Scale consisting of 14 items. Sexual dysfunction was determinate by Scale for Quality of Sexual Function (QSF) as an outcome measure for both genders. The results were analyzed statistically using descriptive methods, the t-test for independent samples. The correlation between the observed variables was tested using Spearman’s rank correlation coefficient (rho). A significance level of 0.05 was used to determine statistically significant differences and associations. Statistical analysis was performed using SPSS for Windows, version 25. The results show inverse correlation between duration of buprenorphine treatment with the score of anxiety r=-0,411; p=0,072 and with sexual dysfunction r=-0,192; p=0,418. Also in our study we got inverse correlation between the buprenorphine doses with the score of anxiety r=-0,136; p=0567 and with sexual dysfunction r=-0,528; p=0,017. But in both cases we got results without statistically significances. Conclusion: Longer buprenorphine treatment with adequate doses give lower scores of sexual dysfunction and anxiety - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DEPRESSION AND ANXIETY FOLLOWING EARLY PREGNANCY LOSS – OCCURRENCE AND RISK FACTORS(Macedonian Association of Anatomists and Morphologists, 2023); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effectiveness of gestalt therapy as anxiety treatment in patients with low back pain(2020-10); ; Damcevska, Jadranka - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Психолошки дисбаланс при хронифициран стрес-пандемија со Ковид 19(2021); Introduction: The outbreak of the coronavirus disease (COVID-19) poses an unprecedented threat to public health. Current measures to control the spread include social distancing, isolation and quarantine, which may trigger mental health problems and create psychological disturbance under this continuous stress. Method and material: The sample (N = 122) constituted two groups: people that have been isolated and people not been isolated. The Goldberg Depression and Anxiety Scale as measures of depression and anxiety, respectively, and Quality of life scale QOLS were administered. A qualitative analysis of the most common verbalizations was made also. Results and conclusion: Depression and anxiety were reported by all respondents. Isolated respondents reported a higher likelihood to exhibit symptoms of depression and anxiety than those not been in isolation. The COVID-19 pandemic, social distance as part of preventive measures, and especially isolation as a preventive and therapeutic method in certain situations of suspected and infected with the virus are undoubtedly associated with increased anxiety and depression, as well as reduced quality of life. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, THE EFFECT OF OF PHYSICAL ACTIVITY ON MENTAL HEALTH IN MEDICAL STUDENTS(Visoka škola za sport i zdravlje, 2021-05-15); Regular moderate physical activity is well known as a beneficial factor for maintaining and improving individual general health including mental health, especially in adolescents during crisis. The aim of the study was to assess the levels of anxiety, depression and perceived stress and their connection with the weekly amount of physical activity in junior medical students during December 2020 COVID 19 restrictive public health measures. The investigation was carried out on 73 medical students (57 females and 16 males) aged 20-22 years, from Medical Faculty, University "Ss. Cyril and Methodius", in Skopje. They answered questionnaires containing biographic data, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Perceived Stress Scale (PSS) and International physical activity questionnaire (IPAQ) by e-mail. Female medical students showed significantly higher levels of anxiety and depression compared to males (p0.05). Pearson correlation between levels of depression and the amount of vigorous physical activity in males was r = - 0.898 while in females it was r= - 0.3251. There was moderate to strong negative correlation between levels of anxiety, depression and perceived stress and the amount of performed moderate physical activity in male medical students. Physical activity could have beneficial effects in male medical students - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Electrophysiological and Psychological Parameters of Learning in Medical Students with High Trait Anxiety(Springer International Publishing, 2018); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, LEVELS OF ANXIETY AND DEPRESSION IN SECOND YEAR MEDICAL STUDENTS DURING COVID-19 PANDEMIC SPRING LOCKDOWN IN SKOPJE, NORTH MACEDONIA(Research in Physical Education, Sport and Health, 2020-12); ; Lence Aleksovska VelickovskaThe aim of the study was to assess levels of anxiety, depression and perceived stress in second year medical students during Covid -19 pandemic spring lockdown in 2020. A cohort of 280 second year medical students, aged 18-20 years, from Medical Faculty, University "Ss. Cyril and Methodius", in Skopje, received questionnaires containing biographic issues, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Perceived Stress Scale (PSS) by e-mail. The response rate was 60 percent. One hundred sixty eight students (41 males and 127 females) completed and returned the questionnaires. Mean values of acquired BDI scores were 10.1 ± 7.6. Mean values for BAI were 15.7 ± 11.3 points. Mean values of acquired PSS scores were 19.5 ± 7.5. Using an arbitrarily defined BDI cutoff point of 21 or greater. Twelve percent of students showed depression accompanied by high anxiety and stress and consequent use of benzodiazepines. Female students showed higher anxiety, depression and levels of stress compared to males. Thirty nine percent of all students had depressive symptoms and 77% of all perceived stress. Almost 75% percent of female second year medical students showed anxiety symptoms, almost half of them showed depressive symptoms and 80% reported moderate to high levels of stress. The prevalence of high anxiety was 22 % in females, while the prevalence of depression was 12%, Seventeen percent of females showed high levels of stress. Continuous pastoral and psychological support as mandatory part of medical education is necessary, especially during major health crisis. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Anxiety in acute myocardial infarction survivors(SHMSHM / AAMD, 2020); ; Sevime Sallahi PasholliIntroduction :Data obtained in some studies indicate that somatic disorders, in a certain percentage, are associated with a mental health problems, whether in a form of two co-existent diseases, whether psychological problems are only associated symptoms and/or response to somatic disease. Anxiety is psychological symptoms frequently encountered in patients suffering from acute myocardial infarct (AMI). The AIM of our study was to determine the percentage of anxiety in two investigated groups of patients with myocardial infarction and to determinate the correlation between socio-demographic characteristic and level of anxiety in survivors of AMI. Material and methods: The study was designed as observation cross-section including 80 patients treated at the university Clinic of Cardiology Skopje , observed as 2 groups : group 1 was presented with patients during hospitalization for AMI, and 2 group were patients survivors after 6 months of the acute coronary event. Anxiety status was assessed using HAMA scale. Results : The two groups of patients did not show significant difference according distribution of gender , smoking , physical activity, stress , age, mean HAMA , BMI , age of education and marital status . In the first group 21 (51,2%) of patients have anxiety symptoms while in second group 25 (64,1%). In our study acute MI was more prevalent in a men but women had a higher risk of anxiety disorders 27,3% v.s (22,7%). In examination groups the anxiety (HAMA score) was positive correlate with socio-demographic and clinical parameters where only we got negative correlate between anxiety with marital status and BMI in the first group and negative correlation with married status, smoking status, physical activity, stress and BMI in the second group . .Conclusion: The results in our study showed indicative representation of anxiety in patients survivors of AMI. So screening for anxiety in all AMI patients is also important because this patients should be treated differently than those who are not anxiety. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, TRAUMA AND ANXIETY DISORDERS THROUGHOUT LIFESPAN: FEAR AND ANXIETY FROM NORMALITY TO DISORDER(Medicinska naklada, 2018); Anxiety disorders are among the most common mental disorders. Anxiety disorders and neurotic fear cause significant disruption of the psychosocial functioning of the individual. In generalized anxiety disorder, neurotic fear appears in the form of fears, expectations, tension, with nothing specifically uncomprehendingly crying anticipation, worry, poor concentration, psychic and physical fatigue, irritability, restlessness, insomnia, sense of near accident etc. Traumatic events in the life of the individual are often referred to as potential relevant factors in the occurrence of psychological disorders. Exposure to long-lasting traumatic experiences in childhood leads to the prolongation and fixation of the emotional state of fear and sadness and the emphasized use of certain defense mechanisms that contribute to the structuring of specific clinical images of anxiety states - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Factors Related to High Anxiety and Depression in Dentistry Students in the Republic of Macedonia(Tehran University of Medical Sciences, 2016-11); ; ; The aim of the study was to identify risk factors related to high anxiety and depression among dental students in the Republic of Macedonia. We performed a cross-sectional study on a cohort of 236 dental students, aged 18 to 25 yr from all study years at Faculty of Dentistry in Skopje, during the second semester of 2012-2013 year. The students anonymously fulfilled self-rating questionnaires regarding stress-provoking factors connected to dental education. They were defined as personal and social problems associated to academic environment (disappointment, financial, interpersonal relations, problems with accommodation, poor quality of education, in-adequate social life, lack of opportunities and administrative problems) caused negative experience and have been most irritating for the students.