Faculty of Medicine
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Item type:Publication, Treatment of acute postoperative pain, the new face of multimodal analgesia(Serbian Society of Pain, Belgrade, Serbia, 2023-05-23) ;Ivana Budic ;Vesna Marjanovic ;Ivana Gajevic ;Jelena LilicMarija Stevic19 Treatment of acute postoperative pain, the new face of multimodal analgesia Ivana Budić1,2, Vesna Marjanović1,2, Ivana Gajević2, Jelena Lilić2, Marija Stević3,4, Marija Jovanovski-Srceva5,6, Dušica Simić3,4 1Department of Surgery and Anesthesiology, Medical Faculty, University of Niš, Serbia; 2Clinic for Anesthesiology and Intensive Therapy, University Clinical Center Niš, Serbia; 3Department of Surgery and Anesthesiology, Medical Faculty, University of Belgrade, Serbia; 4University Children’s Hospital, Belgrade, Serbia; 5University Clinic for TOARILUC, Skopje, N. Macedonia; 6 Medical Faculty, UKIM, Skopje, N. Macedonia ABSTRACT Management of pain remains undertreated in the pediatric population. Multimodal an- algesia (MMA) integrates the use of several analgesic medications, each of which targets a different pain-related receptor, and thereby exhibits its pain reducing effect by way of a different mechanism of action. MMA approach to pain management includes phar- macologic and non-pharmacologic options. Effective postoperative analgesia in infants and young children continues to evolve with innovative methods of therapy using new- er drugs or older drugs introduced via novel routes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Analgesia in Kidney Transplant Recipients(Balkan Cities Association of Nephrology, Dialysis, Transplantation and Artificial Organs, 2021-01); ;Sasho Dohchev; ; Introduction. To our knowledge, currently no consen sus or guidelines exist regarding perioperative and post operative analgesia management in renal transplant re cipients. Methods. We conducted an observational prospective clinical study to evaluate the analgesia management prac tice in kudney transplant recipients. All consecutive pa tients who underwent kidney transplant surgery were enrolled in this observational clinical study. According to current analgesia management practice in our insti tution, patients were divided in two groups: patients who received general anesthesia and epidural analgesia we re group E, and patients who received general anesthesia and i.v. analgesia were group G. The primary outcome measure in this study was VAS score and 24 h analgesia requirements. The second outcome measures were com plications and/or side effects related to analgesia treatment. Results. Group E had lower VAS pain score both at rest and on movement but only in the first 2 h, (VAS at rest E. 3.1±0.3 vs. G. 4.0±0.3, VAS on movement E. 4.2±0.6 vs. G. 4.5±0.3, p<0.05). The pain score by VAS scale did not differ between the groups at 6 h, 12 h and 24 h postoperatively, p=NS. Additionally, a small differ rence was noticed in side effects. Patients in group E had reported more side effects than patients in group G. Conclusion. The study highlighted the variety in clinical practice regarding anesthesiologist preferences for pain management in kidney transplant recipients. This eva luation did not show any difference between anesthetic techniques and clinical results. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Evaluation of pain following the use of scalpel versus electrosurgery for skin incisions in the facial regions(Macedonian Academy of Sciences and Arts / Sciendo, 2018); ;Andrijana Gjorgjeska; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, THE INFLUENCE OF ANESTHESIA IN INTRACAVITARY BRACHYTHERAPY IN LOCALLY ADVANCED CERVICAL CANCER - SINGLE INSTITUTIONAL EXPERIENCE(Department of Anesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2018-05); ; ; Lazareva E.Brachytherapy is important and potentially curative treatment for patients with inoperable locally advanced cervical cancer. Depending on the local finding the radioactive source application can cause serious discomfort to the patient, anxiety, followed by pain. Some patients experienced severe uterine pain. In selected patients, anesthesiological assessment and support is of great importance, because this is a way to realized the treatment. Because of that the anesthesiologist is a vital member of the brachytherapy team. Anaesthesiologists play a key role in the ongoing challenge to provide safe and pain-free conditions for an optimum brachytherapy treatment effect. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, INTRAVAGINAL BRACHYTHERAPY SUPPORTED BY LOCAL ANAESTHESIA IN THE TREATMENT OF ENDOMETRIAL CANCER – SINGLE INSTITUTIONAL EXPERIENCE(Department of Anaesthesia and Reanimation, Faculty of Medicine, “Ss. Cyril and Methodius” University Skopje, R.N.Macedonia, 2020-10); ; ; ; Bojoski PIntravaginal brachytherapy in endometrial cancer is an inevitable part of the treatment. In the early stages of the disease, it signifcantly reduces the risk of local recurrence in the vaginal cuff with low rates of late toxicity. In the advanced stages, it provides palliative control usually with a hemostyptic effect. Brachytherapy may be the only postoperative treatment – monotherapy, or as a boost following the external beam radiotherapy, depending on many prognostic factors. Placing the vaginal applicator deep into the vagina is certainly an uncomfortable feeling, combined with pain, anxiety and discomfort. Local anaesthesia helps in reducing the painful sensations, gives adequate relaxation, but more importantly provides a quality insight into the condition of the vagina, and thus a successful application. Through our experience with the local vaginal anaesthesia with lidocaine 2% gel, we want to emphasize that intravaginal brachytherapy, supported by local anaesthesia, regardless of the degree of pain relief is directly related to successful treatment.
