Faculty of Medicine
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Item type:Publication, COPD prevalence and characteristics among sample of working population(Frontiers Media SA, 2025-05-27); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, COPD PREVALENCE AND CHARACTERISTICS AMONG RETIRED WORKERS(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2025-04); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Prevalence and Characteristics of Chronic Obstructive Pulmonary Disease in Dairy Farmers(Scientific Foundation SPIROSKI, 2022-10-13); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Course of COPD Assessment Test (CAT) Scores During Bacterial Exacerbations of Chronic Obstructive Pulmonary Disease Treated in Outpatient Setting(Bentham Science Publishers Ltd., 2015); ; ; ; Introduction: COPD Assessment Test (CAT) is an 8-items questionnaire for assessment of health status in patients with chronic obstructive pulmonary disease (COPD). Objective: To evaluate the course of CAT scores during bacterial exacerbations of COPD treated in outpatient setting. Methods: We performed an observational, prospective study including 81 outpatients (57 males and 24 females, aged 43 to 74 years) with bacterial exacerbation of COPD. All participants completed CAT at initial visit (i.e. at the time of diagnosis of exacerbation and beginning of its treatment), 10 and 30 days after initial visit. Mean scores of each item, as well as the overall mean score, at these time points were compared. Results: The mean scores for each CAT question at initial visit varied from 2.6 to 3.5, whereas the mean scores for each CAT question 10 days after initial visit varied from 1.7 to 2.6. We registered significant reduction of the mean overall CAT score 10 days after initial visit as compared to its value at initial visit of 6.9 ± 2.7 points (16.8 vs 23.7; P < 0.001). The mean scores for each CAT question 30 days after initial visit varied from 1.3 to 2.4. We registered reduction of mean overall CAT score 30 days after initial visit as compared to its score 10 days after initial visit of 2.9 ± 1.2 points (13.9 vs 16.8; P < 0.005). The mean overall CAT score 30 days after initial visit was reduced for 9.8 ± 4.5 points as compared to its value at initial visit (13.9 vs 23.7; P < 0.001). Conclusion: We found significant improvement in the patient’s health status during recovery from exacerbation as compared to their health status at the time of exacerbation confirming the CAT as an effective tool to measure health status in patients with COPD. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chronic Obstructive Pulmonary Disease in Never-Smoking Bricklayers(ID Design 2012/DOOEL Skopje, 2013-12-15); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Asthma Control Test™ in Assessment of Clinical Asthma Control(ID Design Press, 2009-12-01); ; ; Snezana Risteska-KucBackground. The goal of asthma treatment is to achieve and maintain control of the disease. Objective. To assess validity and reliability of Asthma Control TestTM (ACT) as a patient-based tool for quantifying the control of the disease in the subjects with persistent asthma. Methods. A cross-sectional study including 396 subjects with persistent asthma drown from a population of treated patients was performed. Evaluation of the examined subjects included completion of the ACT, spirometry, and asthma specialist rating of control. Results. The mean derived ACT score in all study subjects was 19.2±3.3. Prevalence of the study subjects with totally controlled (TC), well-controlled (WC) and not well-controlled (NWC) asthma by derived ACT score was 9.1%, 43.2% and 47.7%, respectively. Results from the spirometry showed that in 45% of the study subjects FEV1 value was less than 80%. Prevalence of the study subjects with TC, WC and NWC asthma by asthma specialist rating was 8.1%, 41.1% and 50.7%, respectively. A strong correlation between the derived ACT scores and asthma specialist rating of control was observed (r = 0.51, P = 0.000). Conclusion. Our data confirm the usefulness of the ACT as a valid and reliable screening tool for asthma control. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chronic Obstructive Pulmonary Disease in Never-Smoking Female Workers Exposed to Cotton Dust(ID Design 2012/DOOEL Skopje, 2014-06-15); ; ; Snezana Risteska-KucAIM: Textile workers in their work environment are exposed to airborne particulate from natural and synthetic origin. In the present study we aimed at assessment of prevalence and characterstics of COPD in never-smoking female workers employed at cotton weaving sector in textile manufacture. MATERIAL AND METHODS: In order to assess chronic prevalence and characteristics of chronic obstructive pulmonary disease (COPD) in textile industry we performed a cross-sectional study including 47 never-smoking female cotton workers (aged 36 to 56 years) and an equal number of never-smoking female office workers studied as a control. Evaluation of examined subjects consisted of completion of a questionnaire, baseline spirometry, and bronchodilator reversibility testing. RESULTS: We found higher prevalence of respiratory symptoms in cotton workers with significant difference for phlegm and dyspnea. Majority of the chronic respiratory symptoms in cotton workers were work-related. With exception of the mean value of forced vital capacity (FVC), the mean values of all other measured spirometric parameters in cotton workers were significantly lower than in office workers. The prevalence of COPD was significantly higher in cotton workers than in office workers (11.4% vs. 2.3%, P = 0,027). COPD in cotton workers was significantly associated with age higher than 45 years and with duration of exposure longer than 20 years. CONCLUSION: Our findings support data about relationship between occupational exposure to organic dust in textile workers and persistent airflow limitation. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Bronchial Hyperresponsiveness in Farmers: Severity and Work-Relatedness(ID Design Press, 2014-09-15); ; ; OBJECTIVE: To evaluate the prevalence of respiratory symptoms, lung function and bronchial hyperresponsiveness in farmers, with emphasize to their severity and work-relatedness due occupational risk factors and farming characteristics. METHODS: A cross-sectional survey was performed including 60 cow breeders aged 21 to 65 years, compared to an equal number of agricultural farmers matched by age, job exposure duration, and smoking status. We have used a questionnaire to record the chronic respiratory symptoms, detailed work history, specific farming activities and tasks performed, and smoking history. Evaluation of examined subjects also included lung function spirometry tests, and bronchial hyperresponsiveness testing. RESULTS: We found higher prevalence of work related respiratory symptoms in the last 12 months in cow breeders with significant difference for phlegm (P = 0.039), and wheezing (P = 0.026). Mean values of all spirometric parameters were lower in cow breeders, reaching significance for MEF50 (P = 0.001) and MEF75 (P = 0.000). Significant difference was found for mild bronchial hyperresponsiveness among cow breeders with job exposure of more than 15 years. The risk of developing work-related respiratory symptoms increased significantly with full-time farming, exposure to gases and vapors, and keeping more than 10 cows. CONCLUSION: Our data suggest that workplace exposure in farmers may cause respiratory impairment which is closely related to its duration, characteristics, and intensity. The results suggest that cow breeders in general have higher rates of work-related respiratory symptoms and bronchial hyperresponsiveness than agricultural farmers, whereas their severity increases with an increase in frequency and duration of animal contact. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chronic Respiratory Symptoms and Lung Function in a Sample of Agricultural Workers in Skopje Region(ID Design 2012/DOOEL Skopje, 2014-06-15); ; ; OBJECTIVE: To assess the effect of job exposure and its duration on chronic respiratory symptoms and ventilatory capacity among agricultural workers. METHODS: We performed a cross-sectional study including 120 agricultural workers aged 36 to 53 years, compared to an equal number of office workers matched by age, duration of workplace exposure and smoking status. A questionnaire was used to record the chronic respiratory symptoms, detailed job history, specific job activities and tasks performed, and smoking history. Evaluation of examined subjects also included functional lung testing by spirometry. RESULTS: We found non-significantly higher prevalence of respiratory symptoms in the last 12 months in agricultural workers with significant difference for cough (P = 0.044), and wheezing (P = 0.031). Mean values of all spirometric parameters were lower in agricultural workers, being significantly different for MEF50 (P = 0.001) and MEF75 (P = 0.000). Adverse respiratory effects and lung function deterioration were more expressed in agricultural workers with duration of job exposure more than 20 years than in those exposed less than 20 years. CONCLUSION: Our data suggest that workplace exposure in agricultural workers may lead to respiratory impairment which is close related to its duration. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Respiratory and Nasal Symptoms, Immunological Changes, and Lung Function in Industrial Bakers(ID Design 2012/DOOEL Skopje, 2012-03-01); ; Background: Several studies reported that occupational exposure in bakery may cause respiratory impairment in exposed workers. Aim: To assess the respiratory effects and immunological changes of occupational exposure in industrial bakers. Material and Methods: We performed a cross-sectional study including 43 industrial bakers (20 males and 23 females, aged 34-55 years) and an equal number of office workers, matched by sex, age and smoking status. Evaluation of examined subjects included completion of questionnaire, skin prick tests to common and work-related inhalant allergens, spirometry, and histamine challenge. Results: We found higher prevalence of nasal symptoms in the last 12 months in bakers with significant difference for runny nose (P = 0.033). Prevalence of respiratory symptoms in the last 12 months was also higher in bakers and statistical significance was obtained for cough (P = 0.041) and phlegm (P = 0.023). We found similar prevalence of allergic sensitization to common inhalant allergens in both examined groups, while sensitization to wheat flour and meal flour was registered only among bakers. Measured spirometric parameters were lower in bakers with significant difference for MEF50 and MEF75 (P = 0.004, and P = 0.000, respectively). Prevalence of bronchial hyperresponsiveness (BHR) was non-significantly higher in bakers with significantly higher severity (P = 0.029). Conclusion: Our findings confirm that occupational exposure in industrial bakers may lead to adverse respiratory effects and immunological changes in exposed workers.