Faculty of Medicine

Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14

Browse

Settings

Has files: YesSubject: search.filters.subject.diabetic foot

Search Results

Now showing 1 - 3 of 3
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    IMPACT OF METABOLIC CONTROL IN PREULCERATIVE PHASE OF DIABETIC FOOT
    (SHMSHM / AAMD, 2011-06)
    ;
    Milco Bogoev
    ;
    Gordana Pemovska
    ;
    ;
    Aim. To estimate impact of metabolic disturbances in type 2 diabetic patients (T2DM) and risk for ulceration in preulcerative phase of diabetic foot syndrome (DFS). Material and methods. In this prospective study following parameters are estimated: duration, smoking, BMI, BP, HbA1c, TG, HDL, LDL, fundoscopy and measurements for risk score of DFS. Groups were stratified according measurements : 0–low risk, 1–medium risk, 2-high risk, and 3–very high risk. Results. From 100 patients, 53% were female and 47% male. Mean duration of T2DM 10, 47 ±4, 77 year. Smokers are registered to have 43%, Results of measurements for risk score stratifications have been in V1: score 0-29 %, 1–3%, 2-18% and 3–18% and in V2 in score 0-17 %, 1–39%, 2-19% and 3–25%. BMI was recorded as follows: normal (18-25 kg/m2) 14%, overweighed (25-30 kg/m2) 71% and obese (>30 kg/m2) 15%. Mean HbA1c in V1 was recorded: 0-7,6%, 1-7,9%, 2-8,5% and 3-8,2% (p<0,005), and in V2: score 0-7.26%, 1-7.46%, 2-7, 54% and 3-7, 54%. Systolic BP divided regarding scores is measured: score 0–136 mmHg, 1–142 mmHg, 2–145 mmHg, 3–142 mmHg. Mean levels of TG were: 0-1,97 mmol/L, 1-2,37 mmol/L, 2-2,3 mmol/L, 3-2,6 mmol/L. Mean levels of HDL: 0–1,06 mmol/L, 1–1,02 mmol/L, 2–0.97 mmol/L, 3–1,00 mmol/L. Mean levels of LDL: 0–3,69 mmol/L, 1–4,27 mmol/L, 2–4,05 mmol/L 3–4,09 mmol/L. Conclusion: Bad management of T2DM have impact in early appearance of DFS and early progression from low to high score for foot ulceration.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Diabetic foot with risk for ulceration associated with diabetic retinopathy in type 2 diabetes
    (European Society of Endocrinology, 2011)
    ;
    Nevena Laban Guceva
    ;
    Biljana Jovanovska
    ;
    ;
    Katerina Adamova
    Aim: To define impact of diabetic retinopathy as a risk factor at peoples with type 2 diabetes and diabetic foot. Material and methods: One hundred hospitalized patients with type 2 diabetes, screened for diabetic foot and diabetic retinopathy for 1 year. Clinical examination and laboratory investigations were evaluated. Results: From 100 patients, 53% were female and 47% male, duration of diabetes 10.47±4.77 years. Mean HbA1c was 8%±1.2%. HbA1c<7% had 18%, HbA1c 7–8% had 43% and HbA1c >8% had 49% of patients. At visit 1, risk score for diabetic foot ulceration is: low risk (0) 29%, medium risk (1) 35%, high risk (2) 18% and very high risk (3) 18%). Retinopathy was present with 68% – 53% non prolypherative and 15% prolypherative. According the risk score at visit 1 retinopathy had: in score 0 – 15% non-prolipherative and 0% prolipherative, score 1 – 18% non-prolypherative and 1% prolypherative, score 2 – 11% non-prolypherative and 6% prolypherative, and score 3 – 9% non-prolypherative and 8% prolypherative. After 12 months risk score for diabetic foot was: 0 – 17%; 1 – 39%; 2 – 19% and 3 – 27%. Diabetic retinopathy was present after 12 months 72% of which 51% non-prolypherative and 21% prolypherative. According the risk score after 1 year diabetic retinopathy were present: in score 0 – 6% non-prolyherative and 0% prolypherative, score 1 – 22% non-prolypherative and 3% prolypherative, score 2 – 10% non-prolypherative and 7% prolypherative, and score 3 – 13% non-prolypherative and 11% prolypherative. Conclusion: Association between risk score for foot ulceration and diabetic retinopathy was present. Group with risk score 0 and 1 have more non-prolypherative retinopathy and group with score 2 and 3 have more prolypherative retinopathy (Cross tabulation. Kruskal Wallis test P<0.01).
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Influence of metabolic dysregulation in pre ulcerative phase of diabetic foot
    (2012)
    ;
    Bogoev, Milcho
    ;
    ;
    ;
    Aim. To estimate the impact of metabolic disturbances in type 2 diabetic patients (T2DM) – glucose regulation, obesity, dyslipidemia, hypertension and risk for ulceration in the preulcerative phase of the diabetic foot syndrome (DFS). Materials and methods. In this prospective study 100 T2DM patients were evaluated for 1 year. The following parameters were estimated: duration, smoking habits, BMI, BP, HbA1c, TG, HDL, LDL, fundoscopy and measurements for risk score of DFS. Groups were stratified according to measurements : 0 – low risk, 1 – medium risk, 2- high risk, and 3 – very high risk. Results. Out of 100 patients, 53% were female and 47% male. Mean duration of T2DM was 10.47 ± 4.77 years. Diabetes duration up to 10 years included 52% of subjects and 48 % had a duration of more than 10 years. Forty-three percent were smokers , of which 77.4% were male and 22.6% female. Results of measurements for risk score stratifications are in visit 1 (V1): score 0 - 29 %, score 1 – 35%, score 2-18% and score 3 – 18% and after 12 months in visit 2 (V2) score 0- 17 %, score 1 – 39%, score 2-19% and score 3 – 25%. BMI was recorded as follows: normal (18 -25 kg/m2) 14%, overweight (25-30 kg/m2) 71% and obese (>30 kg/m2) 15% of patients. Mean HbA1c in V1 according the risk score is: 0 - =7.6%, 1- 7.9%, 2 – 8.5% and 3- 8.2% (p<0,005), and in V2: score 0- 7.26%, score 1-7.46%, score 2-7.54% and score 3-7.54%. Systolic BP categorical scores were measured: score 0 – 136 mmHg, 1 – 142 mmHg, 2 – 145 mmHg, 3 – 142 mmHg. Mean levels of TG scores were: 0-1.97 mmol/L, 1- 2.37 mmol/L, 2- 2.3 mmol/L, 3- 2.6 mmol/L. Mean levels of HDL: 0 – 1.06 mmol/L, 1 – 1.02 mmol/L, 2 – 0.97 mmol/L, 3 – 1,00 mmol/L. Mean levels of LDL: 0 – 3.69 mmol/L, 1 – 4.27 mmol/L, 2 – 4.05 mmol/L 3 – 4.09 mmol/L. Diabetic retinopathy (DR) in V1 was present with 68% - 53% non proliferative and 15% proliferative. In V2, DR was present in 72% of which 51% was nonproliferative and 21% proliferative. Conclusion: Suboptimal management of T2DM – high HbA1c, high BP, High TG and high LDL, are multiple factors for early appearance of DFS and have the impact of early progression from low to high score for foot ulceration. In T2DM, patients with duration more than 10 years , HbA1c>8%, TG>2.2 mmol/L, HDL<1.04 mmol/L , LDL>4 mmol/L have a high risk (2) or very high risk (3) score for ulceration.