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Secondary malignant neoplasms in patient with breast carcinoma after radio and chemotherapy
(Македонско друштво на ортопеди и трауматолози = Macedonian Association of Orhopedics and Traumatology, 2017-06)
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Secondary malignant neoplasms (SMN) are cancers caused by treatment with radiotherapy and chemotherapy. They are unrelated to the first cancer that was treated and may occur months or even years after initial treatment. With advances in diagnosis and treatment there is an increasing number of long-term cancer survivors, but also there is growing concern about the risk of radiotherapy and chemotherapy induced malignant neoplasm. In our case report we present a patient that underwent radiotherapy and chemotherapy several times because of recurrence from a well differentiated breast carcinoma with characteristics of cilindroma. After 6 years from the initial treatment a solid renal tumor was found, the histopathological finding from the kidney tissue was “multilocular renal cell carcinoma”. After 11 years skin changes appeared, histopathologically classified as dermatofibrosarcomama.
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Knowledge about human papillomavirus and associated factors among population in the Republic of Kosova
(Институт за јавно здравје на Република Македонија = Institute of public health of Republic of Macedonia, 2022)
Kosumi, Ernad
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Above 70% of sexually active women and men will be infected with human papilloma irus at some point in their lives, and several may yet be infected in more than one circumstance. Around 80% of sexually active women acquire HPV infection, while for the most part, they are asymptomatic with the immune system-mediated clearance of contagion within 6–12 months. High-risk papillomavirus is accountable for causing cancer associated with the cervix, vulva, vagina, anus, penis, and oropharynx. This survey aims to investigate the level of knowledge among residents in the Republic of Kosova regarding human papillomavirus (HPV) infections and HPV-associated diseases and to discover the relationship between these factors. Material and methods: A cross-sectional survey was performed by investigating the knowledge concerning HPV infection in the population aged 18 to 35+ years. The study was conducted in the interval from June 2021 - August 2021. The sample included 500 participants. The questionnaire was anonymous, and participants were free to end the participation at any time, without finishing the questionnaire. Results: More than half of the respondents knew about HPV - 70.0%, and 29.6% did not know. Respondents with secondary and higher education showed 18 times more knowledge for HPV (OR = 18.1311 95% CI: 8.7465-37.5852) than respondents with primary education. To the question Can HPV cause cancer of the cervix, 37.2% (n=186) of the respondents gave a correct answer. The results presented that most participants knew what HPV was (70%), but they also revealed that most participants had low or moderate knowledge about HPV, which was a comparable result with earlier studies. A small number of participants in this survey knew that HPV could heal by itself (12.8%), which was similar to results presented in other surveys. Conclusions: It is important to improve the inadequate knowledge about HPV among the population in the Republic of Kosova. In order to do that, it could be significant to assess which factors affect the knowledge so that young women and all adolescents will get pushed to use protective measures against cervical cancer and have protected sexual behaviour
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Lung cancer in the Skopje region
(Македонско лекарско друштво = Macedonian Medical Association, 2012-04-26)
Pejchinovski, G
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Brcina, I
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Malinska, P
Goal: Report of the five year analysis of patients treated in the hospital of the Skopje region with malignant neoplasms of the bronchus and lungs. Material and operation method: Individual reports for hospital treated persons (Form No 3-21-61A) with clinical diagnosis (C34.0 - C34.9) according to MKB – 10 Revision. With the statistical operation method of the data base, it has been processed 9140 reports of the hospital patients from 2004 to 2008. Results: In the period from 2004 to 2008 in the hospital of the Skopje region, from the total number of the treated patients, 2,02% had clinical diagnosis lung cancer. In relation to the gender structure, 82.9% were men and 17.1% women. The most frequent age structure are the patients between 50 and 59 years with 39,5%. Treated patients at the age of 60-69 years are represented with 33,3%. The five-year analysis shows that 85,1% are patients with clinical diagnosis of lung cancer at the age of 50-79 years. According to MKB 10 Revision the localization are according to code C34.9 represented with 73,9%, and with the code C34.1 or the malignant upper lobe lung is represented with 11,8% Conclusion: In 2008, the number of patients with clinical diagnosis: malignant bronchus and lung were increased for three times compared to 2004. The male patients, almost 5 times more frequently get ill with malignant tumors of the bronchus and lungs compared to female patients. The most common localizations were diagnosed in patients with the following clinical diagnoses: malignant upper lobe lung, then the malignant main bronchus, malignant lower and middle lobe.
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Surgical treatment of cancer on the eyelids and periorbital skin
(Macedonian Surgical Association, 2003)
Mostrov I
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Naceska, A
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Skin cancer of the eyelids and periorbital area produce cosmetical defects, and unlike other skin cancers they also have tendency to damage ocular and adnexal structures by direct invasion or as a result of the therapy. No matter which treatment is used the cancer should be eradicated in toto, without damaging structures and function of the eye, and as the final goal to achieve normal functional and cosmetical result.

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