Faculty of Medicine

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    TUBERCULOUS LYMPHADENITIS IN CHILDREN –14 YEARS OF EXPERIENCE
    (Macedonian Association of Anatomists, 2023)
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    Ivanovska, Julija
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    Nestorov, Hristijan
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    Popova, Gorica
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    Petlichkovska, Sandra
    Tuberculosis (TB)is a major public health problem worldwide. It is one of the main causes of infectious disease and mortality, especially in developing countries. Extra pulmonary tuberculosis accounts for 15-20 % of all types of tuberculosis. Lymph nodes are the second most common localization after pleural TB. In childhood, the most commonly envolved are the hilar lymph nodes. Material and methods: We analyzed the frequency of tuberculous lymphadenitis in children treated at the Institute for respiratory diseses in children-Kozle, in the last 14 years. From January 2006 to February 2020 , we’ve treated 397 children with TB. 55 of them (13,8%), were with tuberculous lymphadenitis. Female children were 34 (61%), the others were male.The most frequent was hilar lymphadenitis at 40 (72%), second localization were cervical lymph nodes in 10( 18%). There was 1 child with submandibular localization,1 supraclavicular, 2children with axillary lymphadenitis and one with mesenterial lymphadenitis. Most of the patients had contact with TB. The diagnosis was confirmed pathohistological in the patients with peripheral lymphadenitis. Tuberculosis treatment was started in all patients based on clinical criteria, exposure, positive TST, chest X-ray, or histological confirmation. All of the patients have finished the treatment successfully. Tuberculous lymphadenitis can be a diagnostic and therapeutic challenge in children. Early diagnosis and timely initiation of therapy lead to favorable therapeutic outcome and reduce complications.
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    Burden and Characteristics of the Comorbidity Tuberculosis-Diabetes in Europe: TBnet Prevalence Survey and Case-Control Study
    (Oxford University Press (OUP), 2019-01)
    Sane Schepisi, Monica
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    Navarra, Assunta
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    Altet Gomez, M Nieves
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    Dudnyk, Andrii
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    Dyrhol-Riise, Anne Margarita
    The growing burden of diabetes mellitus (DM) is posing a threat to global tuberculosis (TB) control. DM triples the risk of developing TB, modifies the presenting features of pulmonary TB, and worsens TB treatment outcomes. We aimed to analyze the prevalence of DM among TB patients and to describe the characteristics and clinical presentation of TB-DM patients in Europe.