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    ESSR Consensus Document for Detection, Characterization, and Referral Pathway for Tumors and Tumorlike Lesions of Bone
    (Georg Thieme Verlag KG, 2017-11)
    Lalam, Radhesh
    ;
    Bloem, Johan L
    ;
    Noebauer-Huhmann, Iris M
    ;
    Wörtler, Klaus
    ;
    Tagliafico, Alberto
    Benign bone tumors are rare but are more common than primary malignant bone tumors. The early accurate diagnosis and reliable differentiation of these rare benign tumors and tumor mimickers from the even rarer malignant tumors with subsequent appropriate treatment or watchful waiting is crucial for the clinical outcome. Bone tumors are often a source of diagnostic and therapeutic uncertainty. Thus this European Society of Musculoskeletal Radiology consensus document is intended to help radiologists in their decision making and support discussion among clinicians who deal with patients with suspected or proven bone tumors. Evaluating these tumors starts with a patient history and physical examination. Radiography is the principal imaging modality and often can reliably diagnose a benign bone tumor by providing information about localization, matrix, aggressiveness, size, and (potential) multiplicity. In a significant number of cases, additional imaging is not necessary. Potentially malignant entities recognized by radiography should be referred for magnetic resonance imaging, which also serves as a preoperative local staging modality, with specific technical requirements. Indeterminate tumors, or tumors in which therapy depends on histology results, should be biopsied. For biopsy, we strongly recommend referral to a specialist regional sarcoma treatment center (RSTC), where a multidisciplinary tumor team, including a specialist pathologist, radiologist, and sarcoma surgeon, are involved. Additional staging modalities are entity specific and should be performed according to the recommendations of the RSTC.
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    Recommmendations for the diagnostic algorithm in lung cancer. Consensus statement of the Macedonian respiratory society and the Macedonian association of pathology
    (Македонско лекарско друштво = Macedonian Medical Association, 2019)
    ;
    Todevski Dejan
    ;
    Rexhepi Arben
    ;
    Tatabitovska Aleksandra
    ;
    Lung cancer is the “number one cancer killer” in the world. Its prevalence is associated to smoking as the primary cause, although air pollution in general and genetic factors are also in stake. The mortality especially from advanced stage lung cancer is still high, although there has been a significant improvement in the past 10 years, mostly due to the introduction of novel compounds such as targeted and immunological treatment. The advances in the treatment of NSCLC have imposed updating of the guidelines for the diagnostic procedure and screening of LC, for the indications for molecular testing as well as for targeted selection of patients who shall benefit the most of the novel treatment modalities. These recommendations shall fulfill their purpose only if implemented in the educational curriculum and if incorporated in the healthcare system strategies.