Faculty of Medicine
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Item type:Publication, Echocardiographic Heart Changes in Pregnancies Complicated with Gestation Hypertension and Preeclampsia(International Scientific Invention Journals, 2019-02-13); ; ; Introduction: Echocardiography as an imaging method is increasingly being used in obstetrics in the management of hemodynamic changes which occur in normal but also in pregnancies with gestational hypertension/preeclampsia. Aim: The aim of the study is to show that some of the heart changes in pregnancies complicated with gestational hypertension and preeclampsia are abnormal and further follow up of these patients is needed. Methods: A total of 81 patients were enrolled in the study. The patients were further divided in two groups. Pregnant women with gestational hypertension or preeclampsia (51) and a control group of normotensive pregnancies (30). A total of 3 echocardiograph exam were made, the first upon entry in the study (28 -34 g.w), the second 2 weeks after delivery and the last 6 months after delivery. Results and discussion: We found several statistically significant results that involve the IVS, PWLV, LKM, left chamber hypertrophy and diastolic function. Diastolic dysfunction usually shows up before systolic dysfunction in the evolution of ischemic/hypertensive cardiovascular disease and is of prognostic value in predicting long term cardiovascular morbidity. The changes seen 6 months after delivery on our last control mean that those changes are permanent and need further prevention strategies. Conclusion: From the noninvasive methods echocardiography is the most favorable method in identifying structural changes and functional changes in pregnancies with hypertension. Echocardiography allows fast, reproducible information and is both safe for mother and fetus. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Neonatal Mortality Trend at the University Clinic of Gynecology and Obstetrics- SKOPJE in the period of 2011-2017(International Organization of Scientific Research (IOSR), 2020-05); Jasna BushinoskaAbstract: INTRODUCTION: Neonatal mortality is the percent of neonatal (infant) mortality of the live- born neonates per thousand live births, in the neonatal period from 0-28 days after delivery, or those born after 22 gestation weeks of pregnancy with birth weight more than 500 g. The neonatal mortality can be divided into early neonatal mortality, which covers the period of 0-7 days after delivery (168h), regardless of the stage of pregnancy, and late neonatal mortality that includes the mortality of live-born infants in 8 until before 28 days after delivery. RESEARCH PURPOSE: The purpose of this paper is to show the percentage of neonatal mortality among live- born neonates at the UCGO-Skopje from 0-28 days after delivery, and the trends of movement of the mortality in the period 2011-2017 year. MATERIAL AND METHODS: This retrospective analysis elaborates on neonatal mortality or mortality in live- born neonates in the period 0-28 days after delivery at the UCGO-Skopje, in the period of 7 years (from 2011 to 2017), in relation to the total number of births in that period. The data is collected from the Info Centre and the histories of the disease of women that gave birth and the newborns at UCGO-Skopje during this period. RESULTS: During this period of 7 years at UCGO-Skopje, there were 36,733 live- born newborns, out of which 912 newborns died in the neonatal period after delivery, from 0-28 days after delivery. The results show that the number of early neonatal deceased newborns, 0-7 days after birth, is higher and is especially significant in the first 24 hours after delivery. The number of late neonatal deaths from 8 until before 28 days after delivery is also high. The total neonatal mortality of UCGO- Skopje in this 7 year period is 24.82 ‰, or 24.8 neonatal deaths in the neonatal period after delivery (0-28 days) per thousand live births. The highest neonatal mortality rate of 33.81‰ was recorded in 2017, while the lowest rate was 17.19 ‰ , recorded in 2015. CONCLUSION: The neonatal mortality rate in Macedonia is quite high, higher than in the countries in our surroundings, the Balkan countries and the mid- developed countries of the world. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, EP1073 The prevalence of squamous intraepithelial lesions according to ethnic affiliation in Macedonia(BMJ Publishing Group Ltd, 2019-11); ; ; Introduction/Background To determine the prevalence of abnormal Pap smears in different ethnic population in women from Macedonia. In our country, Pap smear test is included in the prevention program against cervical cancer to be performed every year in women aged 18 to 65. Methodology We analyzed 1145 female patients, 129 with abnormal Pap smear and 1016 controls. The study was performed in 2015 in women aged 18–65, at the University Clinic for Gynecology and Obstetrics, Private General Hospital Re-Medika, Clinical Hospital ‘Dr. Trifun Panovski’ and in the Primary Health Institution ‘Dr. Emilija Trajkovska’. Results From 1145 analyzed female patients and 129 (11.3%) abnormal Pap smears, we found 9 patients (6.97%) with cell changes from viral infection, 50 (38, 76%) HPV positive patients on cytology test, CIN 1 in 34 patients (26.35%), CIN 2 in 9 patients (6.97%), ASC in 19 patients (14.72%), ASC-H in 6 patients (4.65%), and CIS in 2 patients (1.55%). Furthermore, from all Pap test positive patients, 15 patients had previous cervical conisation and following re-infection. The distribution of ethnicity among abnormal Pap smear women was as following: 107 (82.94%) were Macedonians, 12 Serbians (9.30%) with all types of cervical intraepithelial lesions, 5 Roma ethnicity (3.87%), 3 (2.32%) Albanians, 1(0.77%) Bosnian and 1(0.77%) Turkish ethnicity all with CIN1 lesion. Conclusion Our study showed that the Macedonian population as the predominant population in Republic of Macedonia, was the most prevalent ethnicity with cervical intraepithelial lesions.