Faculty of Medicine
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Item type:Publication, 2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee(Oxford University Press (OUP), 2025-08-29) ;Bueno, Héctor ;Deaton, Christi ;Farrero, Marta ;Forsyth, FayeBraunschweig, Frieder - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DUAL STAINING CYTOLOGY WITH P16/KI67 FOR CERVICAL CANCER SCREENING(University Ss. Cyril and Methodius in Skopje, 2024); ;Kijajova, Ivana; ; Gjirevski, Vlatko - Some of the metrics are blocked by yourconsent settings
Item type:Publication, IMPLEMENTATION OF P16/KI67 DUAL STAINING CYTOLOGY FOR DETECTING CERVICAL DYSPLASIA(University Ss. Cyril and Methodius in Skopje, 2025-09-18); ; ; ; Stanojevik, Verdi - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PREGNANCY IN A PATIENT WITH A CONGENITAL UNICORN UTERUS AND CONIZATION DUE TO CERVICAL CANCER(University Ss. Cyril and Methodius in Skopje, 2024); ;Bushinoska, JasnaIvanov, Jordancho - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Rare case of super-response to Cardiac Resynchronization Therapy in Macedonian patient with Dilated Left Ventricular Non-Compaction Cardiomyopathy(Valley International, 2024-02-24) ;Shopov, Bozhin ;Zafirovska, Planinka; ; Background: Left ventricular non-compaction (LVNC) is rare cardiomyopathy with increased and prominent endomyocardial trabeculations also known as spongy myocardium. It is often found in association with a dilated cardiomyopathy (DCM) and has high incidence of Heart failure (HF). Cardiac resynchronization therapy (CRT) is currently recommended by the available guidelines for selected patients with Heart failure with reduced ejection fraction (HFrEF). Aim: Our case report aims to highlight the therapeutic benefits and superresponse to CRT in a patient with Left ventricular non-compaction cardiomyopathy and HFrEF. Case report: 55-year-old Macedonian male patient with HFrEF, Left bundle branch block (LBBB) remained symptomatic (NYHA III) despite optimal medical treatment (OMT). Echocardiography and CMR findings were in addition to dilated and left ventricular non-compaction cardiomyopathy. Cardiac resynchronization therapy was indicated and 18 months after implantation of CRT-P device we have achieved complete and utter reversibility of systolic myocardial function (EF from 23% to 53%), left ventricular internal diameter was reduced from 90mm to 64mm, left ventricular end systolic volume (LVESV) was reduced from 319ml to 98ml and patient quality of life significantly improved. Conclusion: Cardiac resynchronization therapy is a safe and valuable method of treatment for patients with HFrEF due to dilated left ventricular non-compaction cardiomyopathy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Age and sex differences in the efficacy of early invasive strategy for non-ST-elevation acute coronary syndrome: A comparative analysis in stable patients(Elsevier BV, 2025-06) ;Cenko, Edina ;Bergami, Maria ;Yoon, Jinsung ;Vadalà, Giuseppe - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Sex differences in transradial access failure in ST segment elevation myocardial infarction(Wiley, 2024-09-30); ;Jovkovski, Aleksandar; ;Taravari, HajberKitanoski, DarkoBackground Transradial access (TRA) is now the default access site for PPCI, but technically is a more challenging approach mostly due to anatomic challenges connected to the RA. Aims To assess the differences according to sex in radial artery (RA) access site characteristics during primary percutaneous coronary intervention (PPCI) for ST segment elevation myocardial infarction (STEMI). Material and Methods All 5092 consecutive STEMI patients from our center in the period from March 2011 until December 2017 were examined. The right proximal radial was the “intention‐to‐treat” access in all patients. Preprocedural RA angiography was performed in all patients. Clinical and procedure characteristics, type of radial anatomy variants, need to use another arterial access sites (the primary endpoint for this study), and procedure time were analyzed by sex. Using logistic regression, we selected predictors of radial crossover. Access site bleeding complications and vascular complications were also recorded. Results The STEMI population in this period included 1326 females and 3766 male patients. Females were older (65 ± 11 years) than males (59 ± 11 years, p < 0.0001). Among standard risk factors, hypertension and diabetes mellitus were more common in women and smoking less common. RA anomalies were more frequent in the females (8.8% vs. 6.5%, p < 0.0001), with complex RA loop and tortuous RA twice as frequent in women. Failure of TRA access as the initially chosen site occurred in 4.6% (61) of females versus 2.5% (97) of male STEMI patients (p = 0.0003). The most common subsequent access site was right ulnar access in both groups (57 and 61% respectively). Access site bleeding complications were more common in women 4.4% versus 3.2%, mirrored in hematomas with EASY score III to V. Clinical RA spasm (RAS) was significantly more frequent in females (5.7% vs. 2.2%, p < 0.0001). Multiple regression analysis identified 5 independent predictors for TRA access crossover: previous TRA, anomalous RA, RAS, along with female sex and diabetes. Conclusion Female sex is a significant predictor of more complex TRA in STEMI. Understanding sex differences and predictors for TRA crossover will strengthen the use of different procedural modalities that can help in preserving a successful wrist access in female STEMI patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diabetic Kidney Disease Position Paper of the Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs (MSNDTAO), Macedonian Society of Cardiology (MSC), and Scientific Association of Endocrinologists and Diabetologists of Macedonia (SAEDM)(Walter de Gruyter GmbH, 2024-11-01); ; ; ; Diabetic kidney disease (DKD) is a significant and growing global health concern, affecting a substantial proportion of individuals with diabetes mellitus. This position paper of Scientific societies of endocrinologists, nephrologists and cardiologists has been consensually brought at a couple of mutual meetings, aiming to synthesize current knowledge on screening, diagnosis and staging of DKD, emphasizing the need for an early detection and intervention in order to prevent progression to end-stage renal disease (ESRD). The role of glycemic control, blood pressure management, lipid management and the use of reno and cardioprotective agents, including angiotensin-converting enzyme inhibitors, sodium-glucose co-transporter 2 inhibitors and non-steroidal mineralocorticisteroid receptor antagonist has been entirely considered. Furthermore, we highlight the importance of a multidisciplinary approach in the care of patients with DKD, integrating lifestyle modifications and patient education into the clinical practice. This paper advocates for the implementation of standardized screening protocols and the development of personalized treatment strategies to optimize patient outcomes. By addressing the complexities of DKD, we aim to provide a comprehensive framework for healthcare professionals to enhance the quality of care for individuals at risk of or living with this condition. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Abstract 18529: Early Coronary Revascularization Among "Stable" Patients With Non-ST-Segment Elevation Acute Coronary Syndromes: The Role of Diabetes and Age(Ovid Technologies (Wolters Kluwer Health), 2023-11-07) ;Fabin, Natalia ;Cenko, Edina ;Vadalà, Giuseppe ;Mendieta Badimon, Guiomar
