Faculty of Medicine

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Start date: 1990

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    PREMATURE BIRTH AND COMPLICATIONS OF PREMATURE BIRTH ARE LEADING CAUSES FOR INCREASED NEONATAL MORTALITY
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2025-12-17)
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    Bushinoska, Jasna
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    Ivanov, Jordancho
    Abstract Introduction: Neonatal mortality (NNM) is a mortality in newborns in within the first 28 days after birth. Prematurity and the complications from prematurity are the leading cause for higher NNM rates. A premature newborn is born less than 37 gestational weeks of pregnancy. Low birth weight and low gestational age at delivery and their complications are the leading causes of NNM. Aim of the study: The aim of this paper is to present our results gathered from the material of the newborns treated at the Neonatal Intensive Care Unit (NICU) at the University Clinic of Gynecology and Obstetrics in Skopje (UGOC- Skopje), demonstrating that prematurity and complications of prematurity have been the main causes of increased mortality among newborns, in the analyzed period of 9 months. Material and methods: The study is a cross-sectional prospective research that included 445 newborns who were transferred to the NICU for resuscitation, monitoring and treatment after birth, over a period of 9 months or the period from May 1, 2019 to January 31, 2020, at the University Clinic of Gynecological and Obstetric (UGOC) in Skopje. In this paper, we focused on prematurity and complications of prematurity, which had a significant impact on the NNM of newborns in the NICU, in the analyzed period. Results: The study shows that the leading causes for NNM at UGOC- Skopje were prematurity and complications from prematurity: low gestational age at birth, low birth weight, asphyxia, ARDS, NEC, intracranial hemorrhage, sepsis, congenital anomalies etc. Cesarean delivery, prenatal administration of corticosteroids, higher APGAR score in the 1st and 5th minutes, have a significant impact on the survival of newborns and reduction of mortality in newborns. Conclusion: For a long period of time N. Macedonia was a country with one of the highest NNM rates in Europe. Prevention of prematurity and complications from prematurity, improved health and prenatal service, all this reduce the prematurity and NNM. The reasons for higher NNM are preventable and need programs for health care and education of patients, and better public health service.
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    DECREASING OF NEONATAL MORTALITY AT UNIVERSITY GYNECOLOGY AND OBSTETRICS CLINIC IN SKOPJE OUR MATERIAL
    (Macedonian Association of Anatomists and Morphologists, 2026-02-23)
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    Bushinoska, Jasna
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    Ivanov, Jordancho
    Newborns born after 22 weeks of gestation and with a birth weight greater than 500 g, per thousand live births. For many years, N. Macedonia and the University Gynecology and Obstetrics Clinic in Skopje (UGOC-Skopje), were between leaders inNNMin Europe.From2018, the NNMin Macedonia and on UGOC-Skopje has started to decrease.Aim of the study:The aim of the paper is to present and compare the NNM figures in the Neonatal Intensive Care Unit (NICU) at UGOC-Skopje, in two different periods -the period when the NNM at the clinic was high from 2011-2017 and during 9 months studywhich was madein 2019-2020 on the same clinic, whenthe NNM rate began to fall significantlyon the clinic and in the country.Material and methods:Several previously conducted retrospective studies on NNM at UGOC-Skopje and one prospective study that lasted 9 months from May 2019 to the end of January 2020 were used to obtain and compare the results for NNM rate at the Clinic in this paper.Results:In 9 month,studyin2019-2020, the NNMat the Clinic and in the country,began to record a significant decline.There is a significant decrease in NNM in the group of very premature newborns, bornfrom 28-32 weeks of gestation compared to previous years 2011-2017.NNM rate has significantly decreased and in the group of newborns born with very low birth weight (from 1000-1499 g) and low birth weight (1500-2499 g) compared to previous years.Conclusion:The UGOC-Skopje and N. Macedonia have made progress in the last 5 years in reducing the NNM, which was one of the highest in Europe. This was helped by improved vital statistics, the use of the latest protocols for reducing NNM, and improved technical conditions at NICU
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    A CASE OF TWIN PREGNANCY WITH CONJOINED TWINS
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2023-10)
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    Ivanov, Jordancho
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    Bushinoska, Jasna
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    Ethical considerations in genetic research: Contributions towards a strategy for personalized medicine
    (Macedonian Pharmaceutical Association, Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy, 2025-03-02)
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    Belakaposka Srpanova Viktorija
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    Prominent Transverse Sinus of Pericardium is Uncommon Diagnostic Pitfall on Echocardiography: Clues to Diagnosis
    (Ovid Technologies (Wolters Kluwer Health), 2024-03-16)
    Kotevska Angjushev Marija
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    Dikic, Ana Djordjevic
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    Postoperative emergent agitation on children anesthetized with sevoflurane
    (Lippincott Williams & Wilkins (Wolters Kluwer), 2023)
    Demjanski, Vasko
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    Mikjunovikj derebanova, LJubica
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    Kishman, Aleksandar
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    A Comparative Analysis between TIVA - TCI and Sevoflurane Inhalational Anesthesia – a Pilot Study.
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2024-09)
    Lleshi, Albert
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    Trposka Poposka Angela
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    Chalenges in postoperative pediatric analgesia
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2021-10)
    Demjanski, Vasko
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    Kishman, Aleksandar
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    Evaluation of early complications during placement of long-term central venous catheters in pediatric oncology patients
    (Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2021)
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    Lleshi, Albert
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    Litajkovska, Slavica
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    Demjanski, Vasko
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    Pulmonary Thromboembolism Related to Complicated Knee Surgery. Initial Hospital Treatment and 1 Year Follow Up (Case Report)
    (SASPR Edu International Pvt. Ltd, 2026-08-22)
    Biljana, Poposka
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    Marija, Spasovska
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    Hussain, Nazim
    Abstract Introduction: Pulmonary thromboembolism (PTE) and Deep vein thrombosis (DVT) are common complication following any type of surgery. Orthopedic surgeries have a risk higher than 10% of developing PTE. Therefore, a 2 to 5 weeks is given after the surgical procedure. The aim of this study was to present a case of PTE, preceded by local DVT, preceded by orthopedic surgery despite of prophylaxis with 4000 I.U of LMWH for 21 days and the 1year outpatient follow up afterwards. Materials and methods: A full clinical analysis of a 20 years-old male athlete treated for PTE, DVT and Pleuropneumonia from 22.06.2024 to 05.07.2024 in inpatient setting and a follow up treatment in outpatient setting for 1 year. Results: The patient was admitted with d-dimer count of 3900ng/L, S1Q3T3 ECG pattern highly suspected of underlying PTE. What followed was 2 week long inpatient treatment and stabilization and 1 year-long outpatient treatment, evaluation and finally permanent discontinuation of anticoagulant therapy. Discussion: In an inpatient setting the treatment with LMWH is safer than any other type of anticoagulation for PTE when the right conditions are met and no imminent hemodynamic instability is present. DVT and PTE remain common complications of surgeries especially orthopedic ones. Conclusion: This case highlights the importance of circulatory complications related to surgeries, especially orthopedic ones and how sometimes the given prophylaxis can fail.