Faculty of Medicine

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    KОUNIS SYNDROME - A CASE REPORT OF ACUTE MYOCARDIAL INFARCTION AFTER BEE BITE
    (MIT University, 2024)
    Petreski, Mario
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    Non-ampullary mucinous adenocarcinoma of the small intestine unmasked by persistent anemia: A Case Report
    (Liga-Inform, Ltd., 2026-02-23)
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    Jankoski, D.
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    Kutanoski, D.
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    Kostovska Irena
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    Perforatedsolitarymid-rectaldiverticulumdiagnosedwith colonoscopy:acasereportandliterature review
    (Oxford University Press (OUP), 2026-01-27)
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    Avramoski, Vladimir
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    Gjinoska, Klaudia
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    Kostovska, Irena
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    Stoicovski, Emil
    Rectal diverticulum is an exceedingly rare clinical entity, typically occurring as a solitary lesion or, less frequently, as up to three diverticula. Its development is often associated with underlying conditions such as obstructive defecation syndrome, rectal malignancy, pelvic floor weakness, chronic rectal impaction, obesity, or infection-related muscular atrophy. Although uncommon, rectal diverticulitis represents a surgical emergency requiring timely recognition and management. In this case, a female patient presented with rectal bleeding and secondary anemia. During the clinical course, the patient developed pelvic sepsis secondary to rectal diverticulitis. Appropriate surgical intervention, combined with antimicrobial therapy and supportive management, led to a favorable outcome. Rectal diverticulitis is a rare but potentially life-threatening condition. Awareness of this entity and early diagnosis are essential to prevent severe complications such as perforation and pelvic sepsis. This case highlights the importance of considering rectal diverticulum in the differential diagnosis of lower gastrointestinal bleeding and pelvic infections.
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    Antihypertensive Medication Use and Biochemical Outcomes in Primary Care Patients: A Multicenter Study in Kosovo
    (Oriental Scientific Publishing Company, 2026-03-20)
    Alidema, Fitim
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    Kostovska, Irena
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    Alidema, Arieta Hasani
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    Mustafa, Lirim
    Arterial hypertension remains a major public health challenge that requires longterm pharmacological management; however, antihypertensive therapy may also be associated with metabolic and biochemical alterations. This multicenter retrospective study evaluated the association between antihypertensive drug use and biochemical parameters among primary care patients in Kosovo and compared outcomes across three healthcare centers (Prishtina, Ferizaj, and Gjilan). A total of 900 patients with essential hypertension receiving continuous treatment for at least 12 months were included. Data were extracted from medical records and laboratory registers between January 2024 and January 2025 and comprised demographic variables, treatment regimens (monotherapy or combination therapy), and biochemical parameters, including lipid profile, fasting glucose, renal markers, and electrolytes. Statistical analyses included ANOVA or Kruskal–Wallis tests, chi-square tests, correlation analysis, and multivariate logistic regression. Combination therapy was associated with significantly higher levels of LDL cholesterol, triglycerides, and creatinine compared to monotherapy (p < 0.05), while lipid alterations were more prominent among patients treated with beta-blockers and diuretics (p < 0.01). The use of two or more antihypertensive drug classes independently predicted an increased risk of dyslipidemia (OR 1.8, 95% CI: 1.2–2.5; p = 0.004). No significant differences were observed in glucose levels between the study centers (p = 0.21). Long-term antihypertensive therapy, particularly polytherapy, is associated with clinically relevant biochemical changes affecting lipid metabolism and renal function, highlighting the necessity for routine laboratory monitoring and individualized treatment optimization in primary care practice.
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    CONSERVATIVE TREATMENT OF A CHRONIC WOUND WITH HYDROFIBER DRESSINGS: A CASE REPORT
    (Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2026-06-19)
    Mihajloski, Vladimir
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    Volchevski, Goce
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    Ognjenovikj, Ljubomir
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    MULTIPLI VENTRICULAR SEPTAL DEFECTS – A CASE REPORT
    (MIT University, 2025)
    Trajchevska Margarita
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    Zaku Vegim
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    PYODERMA GANGRENOSUM – A CASE REPORT
    (MIT University Skopje, 2024)
    Kicheec Bojovska Martina
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    Stevkovska, Mare
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    Sterjo Edi