Faculty of Medicine
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Item type:Publication, Ultrasound predictors of compensated liver cirrhosis in hemodialysis patients with hepatitis C(Wolters Kluwer - Medknow, 2013); ; ; Gelev, S - Some of the metrics are blocked by yourconsent settings
Item type:Publication, HYPOMAGNESEMIA AND ALL-CAUSE AND CARDIOVASCULAR MORTALITY IN HEMODYALISIS PATIENTS: ROLE OF INFLAMMATION(Oxford University Press (OUP), 2016-05); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The influence of illness duration before diagnosis on clinical characteristics and outcome in human brucellosis(SAGE Publications, 2019-05-06); ; Our study assesses the influence of illness duration before establishing the diagnosis of brucellosis and initiating therapy on patients’ main clinical characteristics and outcome in an endemic area. The medical files of 297 patients with brucellosis were retrospectively analysed. They were divided into four groups according to illness duration before initiating therapy: <10 days; 11–30 days; 31–90 days; and >90 days. There were significant differences in the occurrences of fever (P = 0.019), focal forms (P = 0.026), spondylitis (P = 0.034) and therapeutic failures (P = 0.006) between the groups. Duration of >30 days before treatment initiation is responsible for more serious clinical presentation and outcome, whereas illness duration of >90 days further worsens the clinical progression in human brucellosis. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Prediction of Outcome from Community-Acquired Severe Sepsis and Septic Shock in Tertiary-Care University Hospital in a Developing Country(Wiley/Hindawi Publishing Corporation, 2012); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association of Systemic Inflammatory Response Syndrome with Bacteremia in Patients with Sepsis(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2019-10-01); ; ; ; The aim of this study was to evaluate the usability of systemic inflammatory response syndrome (SIRS) and commonly used biochemical parameters as predictors for positive blood culture in patients with sepsis. The study included 313 patients aged ≥18 years with severe sepsis and septic shock consecutively admitted in the Intensive Care Unit (ICU) of the University Clinic for Infectious Diseases in Skopje, Republic of North Macedonia. The study took place from January 1, 2011 to December 31, 2017. We recorded demographic variables, common laboratory tests, SIRS parameters, site of infection, comorbidities and Sequential Organ Failure Assessment (SOFA) score. Blood cultures were positive in 65 (20.8%) patients with sepsis. Gram-positive bacteria were isolated from 35 (53.8%) patients. From the evaluated variables in this study, only the presence of four SIRS parameters was associated with bacteremia, finding that will help to predict bacteremia and initiate early appropriate therapy in septic patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Epidemiology of Community-Acquired Sepsis in Adult Patients: A Six Year Observational Study(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2018-07-01); ; ; Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection and it is a major cause of morbidity and mortality worldwide. The aim of this study is to describe epidemiology of community-acquired sepsis in the Intensive care unit (ICU) of the Macedonian tertiary care University Clinic for Infectious Diseases. A prospective observational study was conducted over a 6-year period from January, 2011 to December, 2016. All consecutive adults with community-acquired sepsis or septic shock were included in the study. Variables measured were incidence of sepsis, age, gender, comorbidities, season, source of infection, complications, interventions, severity indexes, length of stay, laboratory findings, blood cultures, 28-day and in hospital mortality. Of 1348 admissions, 277 (20.5%) had sepsis and septic shock. The most common chronic condition was heart failure (26.4%), and the most frequent site of infection was the respiratory tract (57.4%). Median Simplified Acute Physiology Score (SAPS II) was 50.0, and median Sequential Organ Failure Assessment (SOFA) score was 8.0. Blood cultures were positive in 22% of the cases. Gram-positive bacteria were isolated in 13% and Gram-negatives in 9.7% of patients with sepsis. The overall 28-day and in hospital mortality was 50.5% and 56.3% respectively. The presence of chronic heart failure, occurrence of ARDS, septic shock and the winter period may influence an unfavorable outcome. Mortality compared to previous years is unchanged but patients that we have been treating these last 6 years have had more severe illnesses. Better adherence to the Surviving Sepsis guidelines will reduce mortality in this group of severely ill patients. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Internet-delivered cognitive behavioral therapy for posttraumatic stress disorder in international humanitarian aid workers: Study protocol(Elsevier BV, 2017-12); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, EFFECTIVENESS OF INTERNET-DELIVERED COGNITIVE BEHAVIORAL THERAPY FOR POSTTRAUMATIC STRESS DISORDER: A SYSTEMATIC REVIEW AND META-ANALYSIS(Hindawi Limited, 2016-06-20); Cuijpers, Pim - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Comparison of IFN-γ Levels in Children with Tuberculosis Disease (TB) and Latent Tuberculosis Infection (LTBI)(Scientific Foundation SPIROSKI, 2018-11-25); ;