Faculty of Medicine
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Item type:Publication, A 5-Step Approach Protocol Using CareLink Therapy Software in Type 1 Diabetes Patients(SAGE Publications, 2017-11); We have developed a 5-step approach protocol in interpreting SAP using CareLink. The main objective of this pilot study was to assess the usability of the protocol. The main analysis is based on the Therapy Management Dashboard, where five segments are allocated: (1) basic statistics; (2) glucose and insulin overlay; (3) postprandial period; (4) basal/bolus insulin; (5) suspends and sensor. Possible changes are noted on a printed insulin settings page with evaluation of rationale/physiological insulin. Every segment is analyzed with correlation through others with step by step confirmation of possible change. Thirty-four patients (F 18, M 16), age 15.3 ± 7.7 years with total of 128 CareLink downloads were analyzed on monthly basis in a period of 3 months. The patients profile matched our everyday clinical practice, similar to glucose control on patients using insulin pump reported in several studies.3,4 Our data showed increased insulin total daily dose (TDD), due to fine tuning with more bolus dose than the basal rates. The glucose control was improved (as seen in Table 1) with a decreased hyperglycemic and hypoglycemic patterns.A 5-step approach protocol in interpreting SAP using CareLink is simple, convenient, and efficient and should be assessed on the multicenter level and with a wider population. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Social media and diabetes: can Facebook and Skype improve glucose control in patients with type 1 diabetes on pump therapy? One-year experience(American Diabetes Association, 2015-04); ; The aims of the study were to evaluate results from social media (Skype and Facebook) and CareLink software as tools to improve diabetes control in patients with type 1 diabetes using insulin pumps with glucose sensors. To our knowledge, this is the first study where Facebook is used as treatment alternative to regular clinic visits. A total of 56 children and adolescents with type 1 diabetes, ages 14–23, were randomized in two groups: Regular group and Internet group. The Regular group is composed of 29 patients who were treated using standard medical protocol with regular visits at clinic. Data were uploaded at the clinic and interventions (pump settings, basal bolus insulin, and education) were given to the patient by health care professionals. The Internet group was composed of 27 patients who were treated using CareLink software (Medtronic Diabetes). Data were uploaded by the patient at home and interventions (same as Regular group) were given via Facebook (chats) and Skype (sound and video). Both groups had improved A1C at 12 months (Regular group: 7.7 6 1.6% [61 6 17.5 mmol/mol] at baseline vs. 6.6 6 1.5% [49 6 16.4 mmol/mol] at 12 months; Internet group: 7.8 6 1.9% [62 6 20.8 mmol/mol] at baseline vs. 6.4 6 1.6% [46 6 17.5 mmol/mol] at 12 months, P , 0.05 at 12 months) (Table 1). Internet visits were performed with Facebook (54%), Skype (12%), and both Facebook and Skype (34%). Improvement occurred in the first 6 months and was maintained for 6 additional months. There were no differences in acute complications (diabetic ketoacidosis and severe hypoglycemia events), total daily dose of insulin, and weight change in both groups at 12 months. Personalization, presentation, and participation in social media and health care (5) can be tailored to the priorities of the patient Every Internet visit was personalized with patient needs (appointment date and time) and used active patient participation in the decision-making process of diabetes management. We found that social media use allows patients to gain diabetes knowledge and information and interact in their daily insulin adjustments. Moreover, it could help patients cope better with their daily life. This brief trial suggests that patients prefer to communicate with their health care providers using social media. Facebook and Skype can improve diabetes control similar to regular clinic visits. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, THERAPEUTIC APPROACH IN RISPERIDONE INDUCED HYPERPOLACTINEMIA(2022); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Glucose control during kidney transplantation in type 1 diabetes patient on sensor augmented pump: a case report(Springer Science and Business Media LLC, 2018-09); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Temporary use of glucose sensors in type 1 diabetes patients on continuous subcutaneous insulin infusion(2020); ; Background and Aims: The aimof this study was to evaluate the impact of temporary use of real-time continuous glucose monitoring (RT-CGM) on glycemic ontrol in patients with type 1 diabetes (T1D) on continuous subcutaneous insulin infusion (CSII). Methods: The retrospective analysis was performed in patients with T1D on CSII, Minimed 754 (Medtronic, Northridge, CA) with HbA1c>7.5%. Minilink transmitter with Enlite Sensors (Medtronic, Northridge, CA) was used as RT-CGM, which was connected to the CSII for seven days at the beginning, 3 months and 6 months. One-hour training session on how to use the sensor was obtained in all patients prior CGM start. Data was downloaded using CareLink Therapy Management. Software (Medtronic, Northridge, CA) and specific changes in basal and bolus insulin, re-education on carb-counting, physical activity and hypoglycemia/ hyperglycemia were given to the patients. HbA1c was obtained before, 3 months and six months after the study. Results: 76 patients (age 18.4±4.9 years) with diabetes duration of 7.8±2.3 years ans CSII use of 2.7±0.9 years were enrolled in the study. The mean HbA1c decreased from 7.9±0.7% at baseline to 7.1±0.5% at the end of the study (p=0.03). Re-education was performed on the following topics: carb counting 43%, hypoglycemia/hyperglycemia treatment 29% and physical exercise 21% of the patients. Conclusions: Temporary use of CGM can improve glycemic control in T1D patients on CSII. Further investigation on larger groups should be performed to confirm our finding. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, LONGTERM DEFICIENT CALCIUM INTAKE ASSOCIATION WITH BONE TURNOVER MARKERS, HIP AND SPINE BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN(2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ANTHROPOMETRIC INDEXES OF VISCERAL OBESITY RELATIONS TO DYSLIPIDEMIC PROFILE IN METABOLIC SYNDROME(2019); ; Zivkovic, MarijaIntroduction: Visceral obesity and dyslipidemia are the main characteristics of the metabolic syndrome. Objective: The relationship of abdominal sagittal diameter to thigh circumference ratio (SD/T) with anthropometric indexes of visceral obesity waist circumference (WC) and waist hip ratio (WHR) was determined as well as their association with lipid levels. Material and methods: Triglyceride (TG), cholesterol (C), HDL and LDL levels, LDL/HDL, C/HDL as well as WC, WHR and SD/T were determined in 250 healthy women divided into 3 groups according to body fat distribution by their WHR values: 1stgr WHR<0.85; 2ndgr WHR (0.85-1.0) and 3rdgr WHR>1.0. Results: SD/T correlated significantly positively with TG and C (p<0.0001), LDL (p<0.006), LDL/HDL and C/HDL (p<0.0001), also with WC and WHR (p<0.0001), and negatively with HDL (p<0.001). WC and SD/T levels were significantly higher in the 3rd gr (125.16±15.26cm; 0.49±0.38) compared to the 2nd gr (109±14cm; 0.39±0.43) and the 1stgr (88±17cm; 0.32±0.37)(p<0.0001). TG levels in the 3rd gr (1.87±0.69ng/ml) were significantly higher compared to the 1st gr (1.03±0.42ng/ml) and the 2ndgr (1.69±0.92ng/ml) (p<0.0001). HDL in the 3 rd gr was (0.95±0.23ng/ml), significantly lower compared to the 1stgr. (1.24±0.27ng/ml) (p<0.001) and 2n dgr (1.07±0.39ng/ml) (p<0.028). LDL, C/HDL, LDL/HDL and C levels were also significantly higher in the 3rdgr. Conclusion: Visceral obesity was characterized with increased values of WHR, WC and SD/T, which were positively related to dyslipidemic profile. Positive relation of SD/T with atherogenic lipids, atherogenic indexes, WHR and WC, and negative relation with HDL, confirmed it as an important anthropometric diagnostic parameter of visceral obesity in metabolic syndrome. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, BODY FAT DISTRIBUTION CHANGES DURING WEIGHT LOSS DETERMINED BY DUAL-ENERGY X-RAY ABSORPTIOMETRIC INDEXES OF ABDOMINAL OBESITY(2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Trunk/total index determined with dual-energy x-ray absorptiometry in obese women with and without Cushing syndrome(2018); ; - Some of the metrics are blocked by yourconsent settings
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