Faculty of Medicine
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Item type:Publication, PREVALENCE OF AUTOANTIBODIES AGAINST THE PLATELET GLYCOPROTEIN COMPLEXES GP IIb/IIIa, GP Ib/IX AND GP Ia/IIa IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA(Македонско лекарско друштво = Macedonian Medical Association, 2017); ; ;Stojanovic AEfremov DChronic lymphocytic leukemia (CLL) is a malignant disorder characterized by the frequent occurrence of autoimmune hemolytic anemia (AIHA) and autoimmune idiopathic thrombocytopenic purpura (ITP). In this study we analyzed the presence of auto-Abs against the platelet GP complexes GP IIb/IIIa, GP Ib/IX and GP Ia/IIa in 55 consecutive CLL patients using a new antigen specific assay. All patients were simultaneously tested for anti-RBC auto-Abs with the direct antiglobulin test. Antiplatelet auto-Abs against one or more GP complexes was detected in 25 patients (45%). Anti-RBC auto-Abs were detected in 18 patients (33%), 6 of them (11%) had evidence of AIHA at the time the sample was taken. The obtained data show that platelet specific Abs develops frequently in patients with CLL, even more often than anti-RBC auto-Abs. The presence of platelet specific auto-Abs together with thrombocytopenia and normal Hb levels in 16% of patients indicated that ITP may be more common cause of thrombocytopenia in CLL than previously anticipated. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Polymorphisms in human platelet antigen 1, 2, 3 and 5 in patients with idiopathic thrombocytopenic purpura.(2008); ;Trpkovska-Terzieva S; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Single nucleotide polymorphism in FC gamma receptot genes in patients with responsive and unresponsive form of immune thrombocytopenia.(2015); ;Angelovic R ;Trpkovska-Terzieva S; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association of PlA polymorphism in platelet glycoprotein receptor GPIIIa and diabetic retinopathy in patients with type 2 diabetes.(2015) ;Arangelovic E; ; ;Percan VLaban-Guceva N - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Molecular methods in the diagnosis of the myeloproliferative neoplasms-single centre experience.(2015) ;Angelovic R; ; ;Stojanovic A - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Association of single nucleotide polymorphism in platelet glycoprotein receptor GPIa with diabetic retinopathy in patients with type 2 diabetes.(2015) ;Lozance-Bogdanov M; ;Angelovic R ;Laban-Guceva N - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cytotoxic T-Lymphocyte antigen-4 gene polymorphism is not associated with increased risk for chronic lymphocytic leukemia in Macedonian population.(2019) ;Arangelovic E; ;Angelovic R; Trpkovska-Terzieva S - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FCGR2A and FCGR3A polymorphisms and response to rituximab treatment in patients with B-cell chronic lymphocytic leukemia.(2019) ;Angelovic R; ; ;Arangelovic E - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Molecular monitoring and BCR-ABL gene mutations in Imatinib resistant CML patients in our centre.(2019); ;Plasevska-Karanfilska D ;Angelovic R ;Angelkovic E
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