Faculty of Medicine
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Item type:Publication, Correlation of low-energy vertebral fracture, clinical risk factors and bone densitometry in postmenopausal women(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2020); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Influence of vancomycin and meropenem loading on compressive strength of polymethyl methacrylate bone cement(Институт за јавно здравје на Република Македонија = Institute of public health of Republic of Macedonia, Co-publisher Scientific foundation Spiroski, 2025); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Factors Affecting In-Hospital Mortality in Patients with Hip Fracture(Albanian Society for Trauma and Emergency Surgery, 2022-01-20); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Efficacy of Alendronate in Preventing Periprosthetic Bone Loss after Implantation of a Primary Hip Endoprosthesis(Scientific Foundation SPIROSKI, 2022-07); ; ; BACKGROUND: Total hip arthroplasty (THA) is now the gold standard for the surgical treatment of coxarthrosis. The appearance of bone loss after implantation of the hip endoprosthesis over time reduces the primary stability of the implant and leads to progressive loosening of the implant or periprosthetic fracture, which are considered to be the most common causes of hip revision. AIM: The aim of this study is to evaluate the value of alendronate application in reducing periprosthetic osteolysis reduction after implantation of total cementless hip endoprosthesis. METHODS: The study analyzed 50 patients operated on with implantation of a cementless THA. The first group of 25 patients received oral alendronate, calcium, and Vitamin D3 postoperatively. The second group of 25 patients was examined and followed postoperatively without any therapy. Patients were examined by RTG and dual energy X-ray absorption (DXA) methods at 6, 12, and 18 months. RESULTS: The study showed a difference in the values of bone mineral density and bone mineral content in the interval of 6,12, and 18 months, using the DXA method. CONCLUSION: Alendronate therapy after total hip implantation reduces periprosthetic bone loss, maintains bone mineralization, and strengthens the implant. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, THE IMPORTANCE OF FOLLOWING THE ORIGINAL PONSETI METHOD IN TREATMENT OF CLUBFOOT: THE IOWA EXPERIENCE(Македонско друштво на ортопеди и трауматолози = Macedonian Association of Orthopedics and Traumatology, 2022); ; ; Dr. Ignacio Vives Ponseti, an American orthopaedic surgeon with Spanish origin, was born on June the 3rd, 1914 and died at the age 95 in Iowa, USA, on October 18th 2009. He was a brilliant pediatric orhopaedic surgeon, best known for his method of nonoperative treatment of clubfoot, that has become a gold standard of clubfoot treatment. His iconic paper on clubfoot management (1963) is one of the few manuscripts in orthopaedic literature which has radically changed the practice as we know it now. The Ponseti method is easy to learn but, unfortunately easy to modify because modification negatively affects the treatment outcome. That emphasizes the need to learn and follow the exact steps explained by Dr. Ponseti. The first author of this article had the opportunity to learn this method in the place where it all started, guided by Dr. Jose Morcuende, the successor of Dr. Ponseti who continues his legacy in the brightest way possible. After return from the stay at Iowa Stead Family Children’s Hospital 16 patients and 23 feet were treated with best possible adherence to the Ponseti Method. We began using the original Ponseti method in October 2019. Since then, 16 patients, 7 bilateral, 9 unilateral (23 feet in total) have been treated and evaluated. We strove as much as possible to reproduce Ponseti’s strict casting protocol faithfully, as explained in the paper. Usually, for correction of the first three components 4 to 10 casts are necessary, changed on a weekly basis. Equinus is the last deformity to be corrected. In order to avoid prolonged casting and concomitant appearance of rocker bottom deformity, the correction of equinus is facilitated by a simple operative procedure in local anesthesia. Sixty five percent of the patients had good results, 31% had acceptable results, in one patient there was poor result. Compared to the original Ponseti paper from 1963, there is not any significant difference in the results, except the bigger percent of poor results that involves only one patient in our series. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Conoccurence of extraskeletal osteosarcoma and undiagnosed Paget disease in a 49-year-old female(Oxford University Press (OUP), 2025-01); ; Angelovska, TamaraExtraskeletal osteosarcoma (ESOS) represents a rare soft tissue entity, accounting for ⁓1% of all soft tissue malignancies. It is generally considered to have an even worse prognosis than bone osteosarcoma, therefore detailed investigations and proper treatment are required. ESOSs arising in the subcutaneous tissue are even rarer than the ones positioned in deep tissues, and they are considered to have far better outcomes. We present a case of a 49-year-old patient diagnosed with subcutaneous ESOS and Paget disease of the bone, which is not typical for the patient's age, considering that Paget disease of the bone tends to affect a population above 50 years. The coexistence of these two entities in a single patient and all their features make this case unique, and to the best of our knowledge, this is the first case reported. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PATIENT SATISFACTION WITH KNEE ARTHROSCOPY UNDER LOCAL ANESTHESIA AND SEDATION(Department of Anaesthesia and Reanimation, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, R.N. Macedonia, 2024-12-21); ; Popovska, DanicaIntroduction: Knee arthroscopy can be performed under general, regional (spinal or epidural) or local anesthesia with different patients’ satisfaction after surgery. Purpose: The aim of our study was to evaluate the level of satisfaction in patients after knee arthroscopy under local anesthesia. Patients and methods: The study included 52 patients where knee arthroscopy under local anesthesia was performed at the University Clinic for Orthopedic Surgery in Skopje, North Macedonia in the period from February 2021 to February 2022. The study did not include patients with allergy to the used drugs, infection at the portal sites of injection, any previous surgery to the knee, patients with chronic extensive synovitis or gross deformity of the knee (severe varus or valgus knee), as well as those with psychological problems, severe systemic disease, consumption of analgesics or non-steroidal anti-inflammatory drugs within 24 h of surgery, bleeding diathesis or coagulopathy. Evaluation of patients’ satisfaction after surgery was done one to three months later by determining the level of satisfaction, pain during surgery, anesthesia-related postoperative complications and preference of this anesthetic technique in the future. Results: The majority of patients were either very satisfied (84.6%) or satisfied (9.6%) with local anesthesia for knee arthroscopy. Only 1.9% of them were not satisfied at all. Most of the patients reported no pain (80.8%) or mild pain (11.5%) during knee arthroscopy under local anesthesia. Only 1.9% of patients complained of strong or very strong pain during arthroscopy. Of all patients, 51 (98%) had no anesthesia-related problems after surgery except one patient who had redness, pain, swelling and blisters formation on the portal where local anesthetic and adrenaline were previously injected. Most of the patients (96%) reported that they would choose local anesthesia for knee arthroscopy again. Conclusion: Our study showed that most patients had no pain, were very satisfied and would choose local anesthesia for knee arthroscopy again. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, MRI EVALUATION OF BIOLOGICALLY ENHANCED ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2024-04); ; ; Popovska, DanicaPlatelet-rich plasma (PRP) and anterior cruciate ligament (ACL) residual remnant preservation are used today as biologic therapies aimed at stimulating graft healing process after ACL reconstruction, but their synergism has not been established yet. The aim of our study was to investigate the combined influence of PRP and ACL remnant preservation on graft healing after ACL reconstruction and evaluate the results with MRI. Material and methods: The study included 52 patients (45 men and 7 women, mean age 28) divided into 2 groups: group I (control group)-28 patients in whom after the removal of ACL residual bundle, a standard single bundle ACL reconstruction was made, and group II (examined group)-24 patients in whom remnant preserving ACL reconstruction with addition of PRP was performed. The results were assessed 6 months after surgery by MRI evaluation of the graft healing process. Results: Patients in the examined group had more frequently a light hyperintense signal of the intra-articular part of the graft (75% vs. 35.7%, p=0.0046) and absence of synovial fluid at tunnel-graft interface (45.8% vs. 21.4%, p=0.06), average 0.98 cm 2 less surface of bone edema around the graft (p=0.009) than those from the control group. Conclusion: Combined use of PRP and ACL remnant preservation has a positive influence on graft healing after ACL reconstruction leading to faster ligamentization and osteoligamentous integration of the graft.