Faculty of Medicine

Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14

Browse

Settings

Author: search.filters.author.Popova, GoricaHas files: No

Search Results

Now showing 1 - 4 of 4
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Comparison of IFN-γ Levels in Children with Tuberculosis Disease (TB) and Latent Tuberculosis Infection (LTBI)
    (Scientific Foundation SPIROSKI, 2018-11-25)
    ;
    ;
    Simonovska, Liljana
    ;
    Dilberovska, Mirjana
    ;
    Dacevski, Dragan
    This study aimed to evaluate the importance of IFN-γ in the diagnosis of pediatric TB and LTBI and to compare the IFN-γ levels.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Comparison of Oxidative Stress Levels in Healthy Children and Children with Allergic Rhinitis
    (Walter de Gruyter GmbH, 2023-03-01)
    ;
    ;
    ;
    ;
    Background/aim: Allergic rhinitis (AR) is characterized by chronic inflammation of the nasal mucosa. Under the influence of exogenous factors - allergens, reactive oxygen species (ROS) are released during cellular metabolism. They induce a series of pathological changes in the mucosa. Oxidative stress is а result of an imbalance between the production of ROS and the ability to neutralize them. The aim of this study is to compare the levels of oxidative stress between healthy children and children with allergic rhinitis. Material and methods: A total number of 60 children were included (30 healthy children and 30 children with AR). The oxidative stress index was determined by using the FRAS 5 (Free Radical Analytical System) Bravo system. Demographic characteristics, medical history, children's living conditions and eating habits were obtained from the questionnaire. Anthropometric measurements and the absolute number of eosinophils in the peripheral smear were performed on each child. Results: This study showed high oxidative stress index and a significantly higher value of the absolute number of eosinophils in the peripheral smear in children with AR in comparison to healthy children (p<0.05). The group of children with AR had more atopic characteristics and was more exposed to passive smoking than healthy children. Conclusion: Compared to healthy children, children with AR have a high index of oxidative stress, despite of the very high mean value of the concentration of water-soluble antioxidants in serum (PAT test) in the group of children with AR.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    TUBERCULOUS LYMPHADENITIS IN CHILDREN –14 YEARS OF EXPERIENCE
    (Macedonian Association of Anatomists, 2023)
    ;
    Ivanovska, Julija
    ;
    Nestorov, Hristijan
    ;
    Popova, Gorica
    ;
    Petlichkovska, Sandra
    Tuberculosis (TB)is a major public health problem worldwide. It is one of the main causes of infectious disease and mortality, especially in developing countries. Extra pulmonary tuberculosis accounts for 15-20 % of all types of tuberculosis. Lymph nodes are the second most common localization after pleural TB. In childhood, the most commonly envolved are the hilar lymph nodes. Material and methods: We analyzed the frequency of tuberculous lymphadenitis in children treated at the Institute for respiratory diseses in children-Kozle, in the last 14 years. From January 2006 to February 2020 , we’ve treated 397 children with TB. 55 of them (13,8%), were with tuberculous lymphadenitis. Female children were 34 (61%), the others were male.The most frequent was hilar lymphadenitis at 40 (72%), second localization were cervical lymph nodes in 10( 18%). There was 1 child with submandibular localization,1 supraclavicular, 2children with axillary lymphadenitis and one with mesenterial lymphadenitis. Most of the patients had contact with TB. The diagnosis was confirmed pathohistological in the patients with peripheral lymphadenitis. Tuberculosis treatment was started in all patients based on clinical criteria, exposure, positive TST, chest X-ray, or histological confirmation. All of the patients have finished the treatment successfully. Tuberculous lymphadenitis can be a diagnostic and therapeutic challenge in children. Early diagnosis and timely initiation of therapy lead to favorable therapeutic outcome and reduce complications.
  • Loading...
    Thumbnail Image
    Some of the metrics are blocked by your 
    consent settings
    Item type:Publication,
    Rapid SARS-CoV-2 antigen testing compared with RT-qPCR in patients suspected for COVID-19
    (European Respiratory Society, 2021-09-05)
    Popova, Gorica
    ;
    ;