Faculty of Medicine

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    Item type:Publication,
    Подготвителни тестови за воведување на ИМРТ техниката во ИРО Скопје
    (Здружение за медицинска физика и биомедицински инженеринг на Република Македонија, 2007-11-24)
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    Petkovska, Sonja
    При премин од тридимензионална конформална радиотерапија на радиотерапијата со модулиран интензитет неопходно е воспоставување на поинакви и во најголем дел построги тестови за контрола на квалитетот. Еден од најзначајните делови на опремата за радиотерапија со модулиран интензитет е многулистниот колиматор (MLC - Multi Leaf Colimator). Утврдено е дека класичните тестови за контрола на квалитет не се доволни и потребни е подетално испитување на неговото функционирање. Во овој труд се презентирани некои почетни тестови направени на Институтот за радиотерапија и онкологија, Скопје, чија цел е утврдување дали постоечкиот многулистен колиматор ги задоволува барањата за оваа нова техника на радиотераписки третман.
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    A Treatment Planning Comparison of Two Different 3D Conformal Techniques for Irradiation of Head and Neck Cancer Patients
    (Association for Medical Physics and Biomedical Engineering, 2010-11-06)
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    Petkovska, Sonja
    The purpose of this treatment planning study was to compare two different three dimensional conformal irradiation techniques for head and neck cancer patients. For 33 patients with head and neck carcinoma, irradiated according to the classical technique, we computed and evaluated a second irradiation technique in order to optimize the treatment planning protocol. The classical technique, termed “electron-photon fields”, employed two lateral semi-fields (23 fractions) for irradiation of the upper part of the planning target volume that should receive 50 Gy (PTV50) and an anterior and posterior field for the lower part. After the 23rd fraction the lateral fields were reduced from the dorsal side (2 fractions), in order to exclude the spinal cord from them. At the same time the dose to the shielded part of the target volume was delivered with matched electron fields. Finally, after the 25th fraction, the high risk volume was irradiated to the desired dose with plan where the spinal cord was completely shielded. In the new technique, termed “oblique photon fields”, 4 oblique isocentric photon fields were used (25 fractions): two anterior fields that covered the entire target volume that should receive 50 Gy and two posterior fields that covered only half of the target volume in order to shield the spinal cord. Thus, the necessity for using electron fields is eliminated. We kept the plan for irradiation of the high risk planning target volume the same as in the classical technique. The prescribed dose per fraction in all plans was 2 Gy. In both techniques the plans were optimized to the same maximal point dose and the same dose to the spinal cord. The oblique fields plan showed better coverage and homogeneity of the PTV50, except for the patients with positive resection margins receiving postoperative radiotherapy (receiving 66 Gy), where the coverage did not differ significantly. The conformity in both techniques did not differ significantly. The mean dose to the parotid glands was significantly smaller with the oblique fields plan in case of patients with negative resection margins and when all the patients were treated as one group. The preferred treatment technique is thus the oblique photon fields technique, not only because of the superior dosimetric parameters, but also because of the absence of the electron fields which complicate the entire treatment process from dosimetric as well as practical aspect.
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    Transmission Comparison for Two Different Electron Block Materials
    (Association for Medical Physics and Biomedical Engineering, 2010-11-06)
    Petkovska, Sonja
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    The purpose of this work is to compare electron beam transmission, under two different block materials. The first one, cerrobend, consists of 10% cadmium and the second one is cadmium free. Percentage depth doses for open and block fields for all electron energies are measured. Measurements were performed with a plan-parallel ionization chamber over a range of depth from water surface to a depth of 160mm. The fields were defined using a 15x15 electron applicator mounted on linear accelerator. Depth dose curves beyond two alloys are matched and compared. Regarding the results, the percentage depth doses behind blocks correspond very well. The difference between the two alloy curves does not exceed 0.12%. The conclusion of the article is that a coincidence in transmission is acceptable.
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    Item type:Publication,
    Determining the Efficiency of a Commercial Belly Board Device in Reducing Small Bowel Volume in Rectal Cancer Patients
    (Association for Medical Physics and Biomedical Engineering, 2010-11-06)
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    Petkovska, Sonja
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    Angelovska, Natalija
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    Grozdanovska, Biljana
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    The purpose of this treatment planning study was to evaluate the efficiency of a commercial belly board device in reducing the irradiated volume of the small bowel. In this study 10 patients with rectal carcinoma receiving postoperative radiotherapy were included. For each of them we made two computer tomography series in prone position. In the first one the patients were lying on the flat table top, and in the second one they were lying on the belly board device which is under investigation. On both series we calculated and optimized plans according to the standing protocol of our department. From the dose-volume histograms of these plans we compared the volumes of the small bowel irradiated to three dose levels – 15, 30 and 45 Gy. The results showed that the absolute irradiated volumes were significantly smaller in the plans with the belly board device. Based on these results we believe that the employment of this belly board device will reduce the acute and late small bowel toxicity. This should be verified with a clinical study.