Faculty of Medicine

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    Acute Arterial Thrombosis in Anticoagulated Patient for Acute Pulmonary Thromboembolism
    (Nizameddin KOCA, 2023-04-29)
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    Elena Grueva
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    Elma Kandic
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    Oliver Bushljetikj
    Acute limb ischemia is a rare condition in patients with venous thromboembolism (VTE), who already receive anticoagulation treatment. Inflammation is a risk factor for thrombus formation. Patients with active ulcerative colitis, especially at time of exacerbation, are more prone to thromboembolism, both venous and arterial. Risk for thrombosis is 18% higher risk, with also higher risk of bleeding. Up to date, there is no contraindication to any anticoagulant drug in patients with ulcerative colitis. We represent a case of a 73 year - old woman with ulcerative colitis (UC) exacerbation, hospitalized initially for pulmonary thromboembolism, that developed acute arterial thrombosis when switched on novel oral anticoagulant (NOAC).
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    Acute Myocarditis after Pfizer-BioNTech COVID-19 m-RNA Vaccination
    (Scientific Foundation SPIROSKI, 2022-11-30)
    Elena Grueva-Nastevska
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    Planinka Zafirovska
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    Elma Kandic
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    BACKGROUND: Prosthetic mechanical valve endocarditis (PVE) can be manifested as early PVE (acquired perioperatively) and late PVE (resulting from infections unrelated to the valve operation). Causes of both are similar but are late PVE are more prone to less virulent microbes. PVE resulting with paravalvular abscess is confirmed through echocardiography (transthoracic or transesophageal), it results with a high mortality rate especially if it is not early recognized. CASE PRESENTATION: We are presenting a patient with heart failure symptoms caused by PVE after Pfizer-BioNTech coronavirus disease-2019 (COVID-19) m-RNA vaccination. CONCLUSION: The exact mechanism of myocarditis in young men who received the second dose of mRNA COVID-19 vaccine is not yet known. However, this is a rare complication and most people generally recover quickly requiring only supportive treatment. In contrast, the risk of developing myocarditis from the viral infection is much higher.
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    Delayed Presentation of Acute ST Segment Elevation Myocardial Infarction Complicated with Heart Failure in the Period of COVID-19 Pandemic - Case Report
    (YuMed Text Publications, 2020-05-30)
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    Oliver Bushljetikj
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    Elena Grueva
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    Background: Delayed provision of medical care to patients with acute chest pain who failed to seek medical attention on time due to fear from COVID-19 pandemic is a concern among health care professionals. Case summary: We report the case of a 47-year-old man with acute chest pain and dyspnea presenting with ST segment elevation myocardial infarction (STEMI). Patient did not seek medical attention on time due to fear from COVID-19 pandemic. Urgent echocardiography detected left ventricular function with ejection fraction (LVEF) of 35%. Percutaneous coronary intervention (PCI) with direct stenting to LAD as culprit lesion with additional stenting of right coronary artery (RCA) was performed. Patient was discharged clinically stable with heart failure. Discussion: COVID-19 outbreak is associated with significantly lower rate of hospital admissions of patients with STEMI. This worrisome fact might be accompanied by a substantial increase in early and late infarct-related morbidity and mortality. Health care providers and society together must appeal for increased awareness of seeking on-time medical care in case of acute chest pain.