Faculty of Medicine

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Author: search.filters.author.Nikola ChamurovskiHas files: No

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    Continuous effect of migrant crisis on smoking status among migrants
    (European Respiratory Society, 2020)
    Monika Tushevska Mitkovska
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    Nikola Chamurovski
    Introduction: Acknowledging the specific problems of smoking prevalence and cessation in specific high risk populations in 2018, we have conducted a pilot research among migrants in the transitional refugee camps in Bosnia and Hercegovina, to evaluate their smoking habits, showing that migrants crisis has a negative impact on their smoking status. Objective and Method: We aimed to compare and follow the continuous effect of the crisis on the smoking habits, in order to provide data for developing a strategy that can be implemented as an continuous measure in the smoking cessation. From November untill December 2019 we interviewed a total of 368 randomly selected, migrants accommodated in the transitional camps, average length of stay of 70 days. We interwieved 333 men (90%), and 35 women (10%), age of 14-57 with the same questionnaire from the pilot study. Results: 60% were active smokers and 40% were nonsmokers.110 migrants(50%) responded that they have increased the amount of smoked cigarettes since they left they homeland, 65(20%) are smoking less cigarettes compared to the period before they left their homeland, 8(4%) have no difference in the number of smoked cigarettes, 36(16%) have started smoking since they left their homeland. None of the migrants had answered that they quit smoking since they left their homeland. Conclusion: Our data confirmed that the migration crisis has negative impact on the smoking habits of migrants. There was increase of the smoking prevalence and worsening of the smoking status true the migration crisis. We emphasize the need for organizing education and support in the process of quitting smoking for this vulnerable group.
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    Total Eosinophyls, ECP and IL-5 in Peripheral Blood During Treatment with Inhaled Cortikosteroids in Patients with Asthma
    (Turkish Thoracic Society, 2019)
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    Dejan Todevski
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    Monika Tushevska Mitkovska
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    Nikola Chamurovski
    Objectives: The main attribute of asthma is inflammation, which leads to airway remodeling, bronchial hyper-reactivity and reversible or partly reversible airway obstruction. According to GINA, asthma is a chronic inflammatory disorder of the airways in which many cells play a role, in particular mast cells, eosinophils (Eo), and T lymphocytes (GINA). Many cells and mediators take part in creating the asthmatic inflammatory reaction, but eosinophils play a central role. Methods: This study includes 30 patients of the Pulmology and Allergy Clinic, Skopje, with confirmed bronchial asthma, treated with ICS. In all of the patients we followed Eo count, ECP and IL-5 in peripheral blood at the beginning of the study, after 2 and 6 months treatment. Results: At the beginning of the study in all 30 (100 percent) of the patients the serum level of IL-5, Eo count and ECP were increased. Following the parameters during treatment with ICS we registered statistical significant changes in all of the tested parameters. Conclusion: Our conclusion is that the ICS objectively suppress the inflammatory reaction in asthma and the biologic markers (IL-5, Eo and ECP), which we have followed, can measure the accomplished effect. They could be used in every day practice, not only as diagnostic parameters but also as valid therapeutic guides in the treatment of asthma.