DSpace-CRIS

Now showing 1 - 3 of 3

Some of the metrics are blocked by your
consent settings
CHOLANGIOCARCINOMA: CLINICAL AND LABORATORY TECHNIQUES WITH SPECIAL EMPHASIS ON IMAGING TECHNOLOGIES
(Macedonian Association of Anatomists and Morphologists, 2026-02-23)
;
;
Bozhinovska, Biljana
;
Kostova, Masha
;
Bozhinovska Beaka, Gordana
Cholangiocarcinoma is a rare and highly aggressive malignancy of the biliary epithelium, marked by considerable anatomical heterogeneity and a largely nonspecific clinical presentation, factors that frequently contribute to delayed diagnosis. The purpose of this study was to examine the demographic, clinical, laboratoryand imaging characteristics of patients with cholangiocarcinoma and to assess their relationship with imaging-based anatomical tumor classification.This retrospective study included 40 adult patients with histopathologically confirmed cholangiocarcinoma diagnosed in General Hospital “8th September” in Skopje, Republic of North Macedo-nia, between January 2022 and December 2025. Clinical presentation, hepatobiliary laboratory parameters, and imaging findings obtained using contrast-enhanced computed tomography, and most often magnetic res-onance imaging with magnetic resonance cholangiopancreatography were reviewed. Based on imaging find-ings, tumors were classified as intrahepatic, perihilar, or distal cholangiocarcinoma. The study population demonstrated a male predominance (62.5%), with a mean age at diagnosis of approximately 68 years. Perihilar cholangiocarcinoma was the most commonly identified type (55%), followed by distal (27.5%) and intrahepatic tumors (17.5%). Jaundice and pruritus occurred exclusively in patientswith extrahepatic disease, whereas all asymptomatic patients had intrahepatic tumors. Laboratory analysis revealed a marked cholestatic pattern in perihilar and distal cholangiocarcinoma, with substantially higher bilirubin, alkaline phosphatase, and gamma-glutamyl transferase levels compared with intrahepatic disease. Overall, these findings highlight the importance of anatomical tumor classification and support the integrated use of imaging(MR and MRCP), clinical assessment, and laboratory data in the diagnostic evalua-tion ofcholangiocarcinoma.
Some of the metrics are blocked by your
consent settings
BRAIN METASTASIS FROM LUNG CANCER
(Македонско лекарско друштво = Macedonian medical association, 2025-04)
Nedelkoski, Martin
;
;
;
Lung cancer is the leading cause of global cancer incidence and mortality, accounting for 2,4 million new cases and 1,8 million deaths in 2022. The most common symptoms of lung cancer include persistent cough, hemoptysis, weight loss, chest pain and dyspnea. One of the most common metastatic sites of lung cancer is the brain, with intracranial involvement in approximately 20% of patients at the time of diagnosis, and although rare the initial presentation of the disease can derive from this site.
Some of the metrics are blocked by your
consent settings
HYSTEROSALPINGOGRAPHY
(Macedonian Association of Anatomists and Morphologists, 2025-05-02)
;
;
Nedelkoski, Martin
;
To emphasize the role and value of hysterosalpingography (HSG) as a radiological procedure for investigation of the uterine cavity and the patency of the fallopian tubes. This is a retrospective study of a group of 43 patients with infertility examined at the University institute of radiology in Skopje, Republic of North Macedonia during a two months period in 2025. The HSG was part of the infertility examination, evaluation and treatment at the University clinic of gynecology and obstetrics in Skopje, Republic of North Macedonia. The mean age of the 43 patients included in the study was 34.02 years with a range of 20 to 47 years. Most of the participants, 27 (62.8%) had primary infertility. The period of infertility duration was under 5 years in 31 (72.1%) of the women. Hysterosalpingograms showed normal uterine morphology in 31(72.1%) of the included patients, tubal morphology was normal in 35 (81.4%) of the patients, while 42 (97.7%) of the 43 participants had normal cervical findings. The most prevalent uterine anomaly was the arcuate uterus present in 6 (13.9%) of the patients, while the rarest findings were the hypoplastic and the unicornuate uterus, each presenting in only 1 (2.3%) of the patients. Cervical insufficiency was detected in 15 (34.9%) of the patients. Patent tubal dilatation and hydrosalpinx were the most common tubal abnormalities, each finding appearing in 3 (7%) of the patients. Normal tubal patency was present in 36 (83.7%) of the included women, while 3 (7%) of the patients had bilateral tubal occlusion. HSG is a method of choice for demonstration of the uterine endometrial contour, filling of the fallopian tubes and intraperitoneal spillage of contrast with the purpose of establishing tubal patency

Faculty of Medicine

Browse

Filters

Settings

Sort By

Results per page

Search Results