Faculty of Medicine

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Author: search.filters.author.Mustafa AzizoğluHas files: Yes

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    THE IMPACT OF CAUDAL BLOCK ANESTHESIA ON POSTOPERATIVE COMPLICATIONS IN DISTAL HYPOSPADIAS SURGERY: A MULTI-CENTER RANDOMIZED CONTROLLED TRIAL
    (2024-06)
    ;
    Mustafa Azizoğlu
    ;
    Sergey Klyuev
    Aim of the study: This study aimed to assess the effect of caudal block anaesthesia on the outcomes of distal hypospadias surgery. Methods: The patients were randomly divided into two groups. Group 1 (n=) received caudal block anesthesia Group 2 (n=) received no caudal block. The postoperative complications were compared. All patients underwent repair with the TIPU technique. Results: Group 1, consisting of 101 patients, and Group 2, with 78 patients, were evaluated for the prevalence of complications. The findings revealed that meatal stenosis occurred in 6.9% of Group 1 and 7.7% of Group 2, urethrocutaneous fistula in 6.9% of Group 1 compared to 5.1% in Group 2, glans dehiscence in 2% of Group 1 and 3.8% of Group 2, and urethral stenosis was observed in 2% of patients in both groups. Notably, there were no instances of urethral diverticula in either group. Statistical analysis showed no significant differences in the rates of meatal stenosis (p=0.846), urethrocutaneous fistula (p=0.619), glans dehiscence (p=0.453), and urethral stenosis (p=0.793) between the two groups. Conclusion: The study demonstrated that caudal block anesthesia does not significantly increase the postoperative complications in distal hypospadias surgery, with similar complication rates observed in both study groups.
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    Hyperbilirubinemia is a predictor of appendiceal perforation in children: A meta-analysis
    (2023-04)
    Mustafa Azizoğlu
    ;
    Mehmet Hanifi Okur
    ;
    Bahattin Aydoğdu
    ;
    Tuğçe Merve Orbay
    ;
    Ayten Ceren Bakir
    Objective: In this meta-analysis, our goal was to examine the diagnostic utility of bilirubin in identifying complicated from uncomplicated pediatric appendicitis. Materials and methods: Using the databases Embase, PubMed, Scopus, and Cochrane, we carried out a thorough literature search up to 2022. Studies comparing complicated appendicitis (CA) and simple appendicitis (SA) in terms of hyperbilirubinemia in the pediatric population were included. Results: A total of 5 studies with 2740 acute appendicitis patients (1097 complicated appendicitis and 1643 simple appendicitis) were included in this meta-analysis. Five studies have discussed the diagnostic value of total bilirubin (TB). When compared to simple appendicitis, complicated appendicitis had a significantly higher TB count (I2=94%), (WMD=0.18, 95% CI -0.00 to 0.37; P=0.05), DB count (I2=0%), (WMD=0.11, 95% CI 0.04 to 0.18; P=0.002), and IB count (I2= not applicable), (WMD=0.04, 95% CI 0.01 to 0.07; P=0.02). Conclusions: In conclusion, in this meta-analysis, total bilirubin, direct bilirubin, and indirect bilirubin values were higher in complicated appendicitis compared to simple appendicitis. Both total bilirubin and direct bilirubin can be used as diagnostic parameters in childhood appendicitis to differentiate complicated appendicitis from simple appendicitis.