Faculty of Medicine

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    LAPAROSCOPIC INCISIONAL HERNIA REPAIR IN OBESE PATIENT: A CASE REPORT
    (Македонско лекарско друштво = Macedonian medical association/De Gruyter, 2013)
    Mitevski, Aleksandar
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    Inoduction. Laparoscopic repair of ventral-incisional hernia is increasing compared to open technique. It has become a safe method, with low complications and cost comparable with open techniques. Shorter recovery and length of hospital stay are also associated with laparoscopic repair, especially among obese patients. Case report. We present a case of a 42-year-old patient with BMI (Body Mass Index) of 44. He has had three previous open operations for incisional hernia, the last one being two years ago. We performed a laparoscopic IPOM (Intraperitoneal Onlay Mesh) repair with composite mesh using transfascial (transabdominal) sutures and tacks (staples). Conclusions. Low rate of conversion, minimal perioperative morbidity and low recurrence indicate safety in obese and morbidly obese patients treated with laparoscopic approach.
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    ЛАПАРОСКОПСКА ТАПП НАСПРОТИ ПОПРАВКА ПО LICHTENSTEIN; РАН КЛИНИЧКИ ИСХОД
    (Македонско лекарско друштво = Macedonian medical association/De Gruyter, 2020)
    Mitevski, Aleksandar
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    Markov, Petar
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    Introduction. Laparoscopy as a minimally invasive technique has itsplace in inguinal hernia repair. Lower postoperative pain, earlier mobilization and earlier return to usual activities are comparable to an initially high cost of the hospital charge. Also, there is a lower percentage of postoperative complications especially related to the wound. Methods. The study was designed as a prospective randomized controlled study conductedin a three-year-period. Sixty-five patients were randomly assigned into two groups, examined-35 patients treated with TAPP technique and controlled-30 patients treated with Lichtenstein technique. Surgicaltime, preoperative pain, hospital stay, postoperative analgesia, functional status and convalescence were evaluated. The postoperative complications, hematoma, seroma, wound infection and urinary retention were also taken into consideration. Results. A significant diference was found in the surgicaltime favoring Lichtenstein over TAPP technique; postoperative hospitalization was significanlly longer in case of the Lichtenstein procedure. There wasa significant difference concerning postoperative pain and functional status between the groups, as well as in the same group regarding the postoperative days. The percentage of early postoperative complications wassignificantly lower in TAPP group (6.3% versus 16.7%); there wasa significant difference in convalescence (TAPP 4.6±1.2 / Lichtenstein 6.6±1.10). Conclusion. Patients treated with laparoscopic TAPP technique had better early clinical outcome compared to open Lichtenstein technique. It is a result of a lower intensity of the postoperative pain, less postoperative complications which leads to a shorter hospital stay, better functional status and short convalescence.
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    Multivisceral resection for advanced duodenal adenocarcinoma: a case report and review of literature
    (Macedonian Academy of Sciences and Arts, 2013)
    Mitevski, Aleksandar
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    The aim of this paper is to address adenocarcinoma of the duodenum by reporting a case, reviewing the literature and discussing current knowledge, diagnostic modalities and treatment options. We present a case of a 42-year-old patient with duodenal adenocarcinoma at the second portion invading surrounding organs. The patient had a previous history of colon malignancy and was diagnosed with a new tumour formation on regular CT (computed tomography) follow-up. Pylorus-preserving pancreaticoduodenectomy (PPPD) was preformed for this T4 N2 M1 tumor. Duodenal adenocarcinoma is a rare tumor, most frequently involving the second duodenal portion. It has no specific symptoms and it is difficult to diagnose it due to its rarity and clinical presentation. Diagnosis, exact localization, and involvement of lymph nodes and surrounding organs have an impact on surgical strategy and prognosis.
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    Splenectomy for haematological disorders
    (Macedonian Academy of Sciences and Arts, 2014)
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    Mitevski, Aleksandar
    Splenectomy is therapeutic for a large host of conditions. It is a consequence of expanding the list of disorders and liberalizing the indications for splenectomy in many diseases. Red blood cells disorders: autoimmune hemolytic anemia, hereditary spherocytosis, hemoglobinopathies and thalassemia are prone to splenectomy after failure of medical therapy. A variety of thrombocytopenic disorders are improved by splenectomy, and the most common indication for splenectomy is ITP (idiopathic thrombocytopenic purpura). Splenectomy is successful in reversing hypersplenism in a spectrum of disease called myeloproliferative disorders. Relief of symptoms from splenomegaly is also achieved, but it does not affect the inexorable course of the disorder. The role of splenectomy in white blood cells disorders (leukemias and lymphomas) is only palliative and facilitates chemotherapy. Splenectomy in patients with hemathologic disorders imparts a risk of fulminant and life threatening infection "overwhelming postsplenectomy sepsis" that can be obviated by appropriate treatment. Although splenectomy for hemathologic disorders is only therapeutic and not curative, the relief of symptoms and for some disorders facilitation of chemotherapy leads to better quality of life and longer survival.
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    Laparoscopic versus open splenectomy: a single center eleven-year experience
    (Sestre milosrdnice University Hospital Center, 2013-06)
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    Rusiti, Kemal
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    The 11-year experience with open (OS) and laparoscopic (LS) splenectomy at a single center is reported. A total of 201 splenectomies were performed and clinical and demographic data were retrospectively analyzed. Patients were classified according to the type of operation as LS or OS. The mean age of patients was 45.1 +/- 17.1, and 141 patients were male. Out of 43 LS, 40 were done for hematologic causes, and they had a significantly shorter hospital stay compared to OS for hematologic causes (6.87 +/- 2.2 vs. 9.84 +/- 2.9 days; p = 0.000003) and significantly less requirement for blood transfusion (26.2 +/- 93.4 vs. 132.4 +/- 252.3 mL; p = 0.0152). In the OS group, comparison of patients with trauma and those with hematologic causes showed that significantly more males underwent surgery for trauma causes (35 of 43 vs. 16 of 21), hospital stay was longer (18.9 +/- 27.4 vs. 9.8 +/- 2.9 days) and blood requirement higher (708.1 +/- 603.7 mL vs. 132.4 +/- 252.3 mL; p = 0.0004, p = 0.047 and p = 0.000001, respectively). Laparoscopic splenectomy is a safe procedure for spleen removal.