Faculty of Medicine
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Item type:Publication, Neuropsychological profiles and cognitive outcome in patient with left mesial temporal lobe epilepsy (MTLE)(2022); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, VESTIBULAR MIGRAINE-CASE REPORT(2016); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, BASELINE STROKE SEVERITY BEFORE AND AFTER INTRAVENOUS THROMBOLYSIS(League against epilepsy of Macedonia, 2017); ; Mitrevska Velkov JasminaAbstract Introduction Acute ischemic stroke is caused by thrombotic or embolic occlusion of a cerebral artery and is more common than hemorrhagic stroke. Recanalization strategies such as intravenous recombinant tissue-type plasminogen activator (rt-PA), attempt to establish revascularization so that cells in the ischemic penumbra can be rescued before irreversible injury occurs. The National Institutes of Health Stroke Scale (NIHSS) is a systematic assessment tool that provides a quantitative measure of stroke-related neurologic deficit. Aim To evaluate and compare the baseline stroke severity-NIHSS score in acute stroke patients before and after application of intravenous thrombolysis. Material and methods We made a retrospective analysis of 1058 acute stroke patients, hospitalized during a period of April 2014-February 2016, at the Department for Urgent Neurology, University Clinic of Neurology, Skopje. Of them, 27 patients met the inclusion criteria for rtPA application according the guidelines. Results I.v. thrombolysis was administered in 27 patients (2,5%). 9 (33,3%) patients had mild stroke (NIHSS 5-10), 11 (40,7%) patients had moderate stroke (NIHSS 10-15) and 7 (25,9%) patients had severe stroke (NIHSS > 15). After the administration of rtPA, we registered improvement on the NIHSS score in 20 patients (74%). Most of them (18-90%) were improved by 3 points on the NIHSS score (range 1-10 points). Best response to therapy had patients with mild and moderate stroke according to NIHSS scores. In unchanged condition after rtPA application were 2 patients (7,4%) with NIHSS score of 10 and 12, respectively. Worsening of the neurological deficit was registered in 1 patient (3,7%), who had initial NIHSS score of 9 and 1 hour after application of rtPA his NIHSS score increased to 12. 4 patients (14,8%) had lethal outcome. Discussion and conclusion Our study shows the initial experience with i.v. thrombolysis in eligible patients with acute ischemic stroke. More than 70% of the thrombolysed patients improved their functional deficit after the treatment. Intravenous thrombolytic therapy with rtPA is the only approved therapy so far approved for treatment of acute ischemic stroke. Meta-analysis of the trials so far have confirmed the benefit of i.v. thrombolytic therapy in selected patients with acute ischemic stroke. All agree that the earlier the therapy is given, the results are better and the health systems should increase their percentage of stroke patients treated within 60 minutes of presentation to hospital until application of thrombolytic therapy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical Characteristics, risk factors and outcome in patients with in tracerebral haemorrhage(Leage against epilepsy of Macedonia, 2015); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Widespread frontal lobe cortical dysplasia or partial hemimegalencephaly: a continuum of the spectrum(Wiley Online Library, 2019-10); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Micturition and startle-induced reflex seizures in a patient with focal cortical dysplasia in the middle frontal gyrus(Elsevier, 2019-01) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Correlation of CRP as inflammatory biomarker and clinical forms of MS.(Лига против епилепсија на Република Македонија = League Against Epilepsy of the Republic of Macedonia, 2017) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Paraneoplastic neurologic syndroms (case report)(Лига против епилепсија на Република Македонија = League Against Epilepsy of the Republic of Macedonia, 2015); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Young onset subcortical dementia-a spectrum of HIV associated neurocognitive disorder(Лига против епилепсија на Република Македонија = League Against Epilepsy of the Republic of Macedonia, 2017); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical outcome of patients with neuromuscular disease and acute respiratory failure treated with mechanical ventilation - four years experience(League Against Epilepsy of the Republic of Macedonia/Лига против епилепсија на Република Македонија, 2013); ;