Faculty of Medicine
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Item type:Publication, Tretman na plevralen empiem(Македонско лекарско друштво = Macedonian medical association, 2023-09-21); ;Cholanceski R; ;Jakupi N - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Preoperative carbohydrate load and the level of postoperative pain, anxiety and nausea in patients undergoing breast surgery(Serbian Pain Society, Belgrade, Serbia, 2022-10); ; ; ; Background: Preoperative caloric load, 3 hours before the surgery has been de- bated in relation to major surgeries and as a part of the Enhanced Recovery After Sur- gery Protocols (ERAS) during the last decades1. Its influence on the postoperative com- plications and unwanted events has been elaborated and proved in several studies1,2. However, its influence in nondiabetic patients and its correlation to postoperative pain and anxiety in breast surgery has still not become a part of the protocols. The aim of our study was to analyze the occurrence of postoperative pain, anxiety, nausea and glycemia in patients undergoing breast surgery. Method and material: In a prospective study 40 female patients, aged 40-60, non-diabetic (preoperative Hb A1c<5.7mmol/l), ASA I, II, scheduled for radical mas- tectomy at the University Clinic for thoracic surgery, Skopje from January 2022 to April 2022 were included in the study. In the study patient with diabetes melitus, EF<50%, after hemotherapy, with renal or endocrine diseases were not included in the study. Patients, with computer-based randomization were divided into two groups. Patients in Group A received 3 hours preoperatively carbohydrate drink* of 200 ml, whereas pa- tients in group B received an equal amount of tap water. All patients underwent stand- ardized anesthesia and post-operative analgesia protocol. In all patients we analyzed the demographic data, the level of glycemia, and according to the Visual Analog Scale (VAS in mm) the level of pain, anxiety, and nausea 12 and 24 h postoperatively. Furthermore, we analyzed the level of additional analgesia needed postoperatively with tramadol. Results: Preoperative demographic characteristic in the groups were homoge- nic. Mean age in group A was 56.3 years + 4.7 SD, while in group B was 56.7 years + 2.9 SD. Level of anxiety was moderate in both groups preoperatively (after the drink), but not significantly lower in the patients in the first group (6.3 vs 7.7) while pain and nausea were low for that time measurements for both groups. On the other hand, 12h 318 PROCEEDINGS postoperatively pain was on average 2.3 vs 4.5; anxiety was 5.3 vs 5.7 and nausea oc- curred with average score of 5.2 and 2.7 and glycemia was significantly higher in the group B in respect to the groups. 24 h after the operation was no significant difference in the VAS score for all three parameters between the groups. In the group B 50% of the patients needed additional analgesia during the first 12 h. Conclusion: Carbohydrate loading with 200ml of solution 3h preoperatively low- ers the pain and the need for additional analgesia during the first 12 h postoperatively. Furthermore, it influences on lowering the postoperative glycemia, nausea and anxiety in female patients undergoing breast surgery. However, more randomized studies are needed. *the content of the solution was: water, maltodextrin, fructose, sodium citrate, aroma with osmolarity of 240mOsmol/L. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PNEUMOTHORAX TREATMENT IN PATIENTS WITH EMPHYSEMATOUS LUNGi DISEASE WITH TWO DIFFERENT TECHNIQUES.("Ss Cyril and Methodius"University, Faculty of Medicine, Skopje, R. N. Macedonia, Department of Anesthesia and Reanimation, 2017) ;Jakupi N; ;Dzikovski I; Maric NObjective: to compare the outcomes of thoracotomy and video-assisted thoracoscopic sur- gery (VATS) in the treatment of pneumothorax in patients with emphysematous lung disease. Заклучок: Според освртот врз литературата јасно е дека ларингоскопијата и интубацијата може да предизвикаат хемодинамиска нестабилност со појава на неспецифични варијации во ST-T сегментот. Тоа е несакан сучај на кој секогаш треба да се мисли, особено кај хипертензивните пациенти кои се третирани со RAS антагонистите, кои предизвикуваат значаен пад на артерискиот крвен притисок, кој е пак одговорен за коронарната вазоконстрикција и промените во големината на ST сегментот. Главните промени се случуваат 5 минути по интубацијата. Method and Material: in prospective study we analyzed the level of postoperative compli- cations, duration of drain presence, total drain collection, site infections, length of hospital stay (LOHS) and recurrence of pneumothorax in two groups of patients. Group OT (n=12) included patients undergoing open thoracotomy and group VATS (n=12) underwent VATS for primary pneumothorax treatment. | 26 | Number 3. December 2017 | 27 | ABsTrACT results: Demographic data between the groups was homogenous. Duration of drain presence was 4.08 vs. 3.8 days in respect to the groups. Statistically significant large amount of drain collection was found in the OT group (604.1 ml vs. 391 ml). Length of hospital stay was statis- tically longer in group OT (p=0.02). Two patients had recurrent pneumothorax in VATS group. Conclusion: According to our study patients, who undergo VATS, postoperatively have lower amount of drain collections, have drain presence for less days, have less days spent in the hospital, but have increased recurrence rate. Even though our study has small number of patients included, it opens a door to larger study to confirm the results. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Open esophagectomy as a treatment of choice for esophageal cancerand a successful outcome at the University Clinic in Skopje, North Macedonia: a case report(University Ss. Cyril and Methodius, Medical Faculty in Skopje, 2022); ; ; ;Jakupi NKaragjozov PEsophageal cancer is one of the least studied cancers and has high mortality rates, mainly because it is diagnosed at rather late stage. It requires urgent attention and in patients where surgery is feasible, it is immediately performed. There is a considerable variation in terms of the surgical approach in different countries, but open esophagectomy is a treatment of choice. This study describes a case of esophageal squamous cell carcinoma that was successfully treated with open esophagectomy and therefore provides information about the present state of esophageal cancer surgery at the University Clinic in Skopje, North Macedonia. The patient underwent clinical examination after which she was admitted to our department for surgical treatment. Esophagography and CT imaging were done pre- and postoperatively and no complications were noted after surgery. The patient was discharged and a written informed consent was obtained for publication of this case and any accompanying images.
