Faculty of Medicine
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Item type:Publication, FEVER OF UNKNOWN ORIGIN: CLINICAL CHARACTERISTICS AND ETIOLOGICAL SPECTRUM(Здружение на инфектолози на Република Македонија = Macedonian Society of Infectious Diseases, 2024-10-06); ; Objective: This study aimed to provide an overview of the etiological distribution, clinical features, and laboratory findings among patients with classic fever of unknown origin (FUO) admitted to the University Clinic for Infectious Diseases and Febrile Conditions in Skopje. Materials and Methods: All participants underwent a comprehensive medical history review, physical examination, and predetermined laboratory investigations. The final diagnosis was established using specific diagnostic procedures guided by potential diagnostic clues (PDCs). After diagnosis, patients were categorized into infectious and non-infectious FUO groups. Results: The analysis included 47 participants, with a mean age of 57 years, the majority of whom were male. Fever lasted an average of 30 days, with a median temperature of 39 °C. Infections accounted for 53.2% of cases, followed by inflammatory non-infectious diseases (25.5%), malignancies, and other miscellaneous conditions (10.6%). The most frequent symptoms were myalgia, arthralgia, fever, sweating, and malaise. On physical examination, hepatosplenomegaly, heart murmurs, joint swelling, and skin rashes were the predominant findings. Significant laboratory abnormalities included elevated ferritin and procalcitonin levels across groups. Conclusion: Specific variations in clinical presentation and laboratory findings may help facilitate a more rapid differential diagnosis of classic FUO. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, RECURRENT CLOSTRIDIOIDES DIFFICILE COLITIS – CASE REPORT(Peytchinski Publishing Ltd., 2024-10-06); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, METHICILLIN-SENSITIVE STAPHYLOCOCCUS AUREUS BACTEREMIA AND MENINGITIS ASSOCIATED WITH SPINAL AND PSOAS MUSCLE ABSCESS – CASE REPORT(Peytchinski Publishing Ltd., Pleven, Bulgaria, 2024-10); ; ; Rangelov, GoranMethicillin-sensitive Staphylococcus aureus (MSSA) can cause a range of severe infections, including bacteremia and meningitis. While MSSA-related bacteremia and meningitis are serious on their own, they can also be associated with complex complications such as intraspinal and psoas abscesses. We report a case of a 72-year-old male with symptoms including lower back pain, leg weakness, malaise, fever and headache. Initial laboratory results showed leucocythosis, hyponatriemia and elevated CRP, while cerebrospinal fluid analysis indicated significant pleocytosis and neutrophilia. After admission, three blood cultures were obtained, all of which isolated MSSA. During hospitalization, a CT scan of the thorax and MR of the spine were performed, revealing bilateral pleural effusion, L5-S1 intraspinal abscess, and an abscess in the ileopsoas muscle. After 6 weeks of antibiotic therapy, a follow-up MRI was performed, which showed regression of the abscesses. This case underscores the severe complications of Staphylococcus aureus infection, including meningitis, sepsis and abscesses. Effective management relies on prompt diagnosis, comprehensive evaluation, and targeted antibiotic therapy. The patient’s positive outcome highlights the importance of early recognition and tailored treatment in complex infections. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical outcome in hospitalized patients with COVID-19 and Diabetes(Macedonian Infectious Diseases Society, 2022-11-11); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Phenotypic characteristics and clinical outcome in hospitalized patients with COVID-19 and diabetes(AMALTEA Medical Publishing House, 2022-12-31); ; ;