Faculty of Medicine

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    Amyand's hernia with gangrenous perforated appendicitis and diffuse peritonitis-case report
    (Oxford University Press (OUP), 2025-11)
    Gelevski, Radomir
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    Manevska, Vesna Jovanovska
    Amyand's hernia, the presence of the vermiform appendix within an inguinal hernia sac, is a rare clinical entity (0.2%-1.7% of inguinal hernias). Acute appendicitis within the sac is rarer still, occurring in only 0.1% of cases. We describe a male patient presenting with an incarcerated right inguinal hernia, who developed diffuse peritonitis after manual reduction. Laparotomy revealed gangrenous perforated appendicitis with purulent peritonitis. Appendectomy, partial omentectomy, and peritoneal lavage were performed. The patient recovered uneventfully. Amyand's hernia complicated by perforated appendicitis is an exceptional surgical emergency. Early recognition and prompt surgical management are crucial for favorable outcomes.
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    Pancreas and duodenum herniation in a giant inguinal hernia sac in a patient with severe scoliosis: a rare case report
    (Oxford University Press (OUP), 2025-07)
    Gelevski, Radomir
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    Giant inguinal hernias (GIHs) are rare clinical entities, typically containing omentum or small bowel. Involvement of retroperitoneal organs, such as the pancreas and duodenum, is exceedingly uncommon due to their fixed anatomical positions. We report a unique case of a 52-year-old male with a longstanding right GIH and severe scoliosis, in whom preoperative imaging and surgical exploration revealed herniation of the pancreatic head and duodenum into the hernia sac. Contributing factors included altered retroperitoneal geometry from spinal curvature, reduced abdominal wall tone, and congenital right hip displacement with associated functional limitation. Incidental findings of multiple left hepatic duct calculi raised concerns for biliary stasis due to chronic duodenal displacement. This case highlights the importance of considering atypical hernia content in patients with longstanding hernias and complex musculoskeletal deformities, and underscores the role of comprehensive imaging and multidisciplinary assessment in surgical planning.
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    Uncommon degloving intestinal injury accompanied by complete disruption of the rectus muscles in patient with seat belt sign: a case report
    (Oxford University Press (OUP), 2025-07)
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    Gelevski, Radomir
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    Argirov, Ivan
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    Ulusoy, Cemal
    Blunt abdominal trauma rarely causes injury to hollow intraabdominal viscus. Still, in victims with seat belt sign, a high index of suspicion should be raised. Additionally, accompanied injury to the abdominal wall muscles is reported. We present a case of a male patient injured in a high-velocity car accident presented with seat belt sign and peritoneal signs. Laparotomy revealed uncommon degloving injury of the small intestine with additional mesentery lesions and lacerations of the ascending and descending colon. Concomitant transection of both rectus abdominis muscles was also encountered.
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    Opioid sparing effect of transversus abdominis plane (TAP) block in open ventral hernia repair: case series
    (Wolters Kluwer, 2022-06)
    Toleska, Marija
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    Dimitrovski, Aleksandar
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    Trposka, Angela
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    Background: Open ventral hernia repair surgery is characterised with pain that arises from skin, muscles of the anterior abdominal wall and parietal peritoneum. Transversus abdominis plane (TAP) block can be suitable for these operations and can lower usage of opioids during surgery and in the postoperative period. Case report: We represent five patients, all ASA classification 2, scheduled for open ventral hernia repair surgery. After induction to standard general anesthesia with 2 mg midazolam, 100 µgr fentanyl, propofol 2 mg/kg, and rocuronium bromide 0.6 mg/kg, ultrasoundguided TAP block was performed with 20 ml 0.25% bupivacaine + 4 mg dexamethasone on both sides before surgical midline incision. Anesthesia was maintained with sevoflurane 0.7-1 MAC. Pain was measured first 48 hours after surgery with numeric rating score (NRS) from 1 to 10, where for NRS 4-6/10 1 gr metamizol was given, and for NRS 7-10/10 1 mg/kg tramadol was administered. Opioid consumption during surgery and in the postoperative period was measured too. The first three patients have pain 22 hours after surgery with NRS 4/10, other two patients have pain 25 hours after surgery with NRS 6/10 and all received 1 gr metamizol. Next complaint was 34 and 46 hours after surgery in all patients with NRS 4-5/10 and 1 gr metamizol was given. Total opioid consumption during surgery in all patients was 150 µgr fentanyl and none of the patients received opioids in the postoperative period. Discussion: Pain in open ventral hernia repair operations is from somatic origin and can lead to high pain scores in the postoperative period, bigger opioid consumption and prolonged stay in hospital.1 Bilateral TAP block is ideal for treatment of somatic pain and given together with dexamethasone can prolong analgesia in first 48 hours after surgery. References: 1. Zhang D, Zhou C, Wei D, Ge L, Li Q. Dexamethasone added to local anesthetics in ultrasound-guided transversus abdominis plain (TAP) block for analgesia after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials. PLOS ONE 14(1): e0209646. https://doi.org/10.1371/journal.pone.0209646 Learning points: TAP block given with steroids before surgical incision achieves prolonged analgesia during and after surgery, minimise opioid consumption and better pain control.
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    Low-grade malignancy glomus tumor of the abdominal wall: a case report and literature review
    (Oxford University Press (OUP), 2023-12)
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    Gelevski, Radomir
    Glomus tumors are painful neoplasms arising from the glomus body (responsible for body temperature and blood pressure regulation) in the skin. Although mostly present in the interdigital areas, glomus tumors can arise elsewhere. The vast majority of them are benign. Rarely, malignant variants are reported and are associated with the potential for local infiltration and metastatic dissemination. The abdominal wall location of glomus tumors is extremely rare regardless of whether they present as benign or malignant. We present a case of a 58-year-old female patient with a low-grade malignancy infiltrative glomus tumor of the abdominal wall.
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    Risk Factors for Early Postoperative Complications after Surgery for Crohn's Disease
    (Centre for Evaluation in Education and Science (CEON/CEES), 2014-09-01)
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    Milev, Ilija
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    Gelevski, Radomir
    <jats:title>Summary</jats:title> <jats:p> The aim of this study was to show the influence of various risk factors on early postoperative complications following surgery for Crohn’s disease (CD). In this review, an online internet database was searched, and also systematic review of the literature was performed. Three different studies from different countries were analyzed and compared with the results obtained in our University Clinic of Digestive Surgery - Skopje. The first review shows the influence of positive resection margins in CD on septical complications occurrence in patients undergoing ileocolic resection for CD at the Tel Aviv Medical Centre - Israel. The second review shows the risk factors for complications after bowel surgery in Korean patients with CD using data from the Asan Medical Centre - Seul, Korea. The third review shows that the delay of surgery is associated with inferior postoperative outcome in patients treated for perforating Crohn’s ileitis, and the study was conducted using data from the medical records of patients treated at the Department of Surgery at the University of Regensburg, Germany. Finally, we analyzed the influence of the most common risk factors on early postoperative complications in patients that underwent surgery for Crohn’s disease in a five-year period at the University Clinic of Digestive Surgery in Skopje, Macedonia and compared them with the results in the aforementioned articles.</jats:p>