Faculty of Medicine
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Item type:Publication, The role of rapid chromatographic immunoassay tests in acute poisoning: two case reports and literature overview(Edizioni Minerva Medica, 2026-03-22); ; ; ; This report through the presentation of two case studies highlights the common problem with false-positive urine drug screen faced by many physicians to the emergency and toxicology departments. Case 1: a 29-year-old male patient was admitted after acute poisoning with analgesics/antipyretics (Caffetin Cold, Caffetin); diazepam; amlopin. Case 2: a 56-year-old female patient was admitted with impaired consciousness. According to the data obtained from the patient’s family they suspected that she took the following drugs: Zanfexa, Zalasta and Diazepam. A rapid chromatographic immunoassay urine test was performed in both patients for the following substances: opiates, amphetamines, metamphetamine, MDMA (3,4-methylenedioxymethamphetamine), oxycodone, phencyclidine, cocaine, methadone, barbiturates, cannabinoids, benzodiazepines, tricyclic antidepressants, and tramadol. Case 1 was positive for opiates, benzodiazepines and amphetamines. Gas chromatography mass spectrometry and high-performance liquid chromatography were used and confirmed the presence of caffeine, codeine, paracetamol, propyphenazone, pseudoephedrine, dextromethorphan, nordazepam, ramipril and amlodipine in urine sample. Case 2 was positive for tramadol and benzodiazepines. Gas chromatography mass spectrometry was used and confirmed the presence of venlafaxine, its metabolites and nordazepam in serum and urine samples. If a false-positive urine screen result is suspected, nonimmunologic techniques, such as gas chromatography/mass spectrometry or high-performance liquid chromatography, are necessary for confirmation. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Late emergence of myasthenia gravis complicating envenoming by Vipera ammodytes(Elsevier BV, 2026-10-01); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Acute severe poisoning with disinfectant in senior aged patient-case report and overview of literature considering age influence on treatment decision in alcohol-based intoxications(2021); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Neurotoxicity and Renal Impairment in a Patient with Acute Poisoning with Antipsychotic Drugs-Literature Review(2021-05); ; ; Kostadinovski, KristinNeuroleptic malignant syndrome is a rare, severe and potentially fatal condition characterized by hyperthermia, muscle rigidity, changes in mental status (delirium, altered consciousness). There are many risk factors responsible for development of this syndrome such as the use of high-dose, high-potency and long-acting antipsychotic drugs, rapid increase in the dosage, using multiple antipsychotic drugs or other medications like antidepressants and mood stabilizers, especially lithium. A correlation between chronic kidney diesease and sudden lithium intoxication has been postulated, but the relationship between both remains unclear. We present here a case with neurotoxicity, rhabdomyolysis, renal impairment and hyperparathyroidism caused by acute poisoning with lithium, haloperidol, diazepam. The purpose of this case report is to increase awareness and vigilance of the fact that concurrent use of multiple antipsychotic and other drugs may cause multiple organ failures. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cardiovascular toxicity in acute tricyclic antidepressant (Amitriptyline) overdose(Elsevier BV, 2006-09) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Influence of Duration of Heroin Dependence on Humoral Immunologic Indicators(American Society of Addiction Medicine, 2016-11);