Faculty of Medicine

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Author: search.filters.author.Arnautovska, BogdankaLanguage: search.filters.language.English

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    Comorbid Conditions in a Cohort of Inpatients with SARS-CoV-2 and their Association with In-Hospital Mortality During the Early Phases of the Pandemic
    (Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2023-12-01)
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    Cibrev, Dragan
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    Chamurovski, Nikola
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    Introduction: Studies determined that age and associated comorbidities are associated with worse outcomes for COVID-19 patients. The aim of the present study is to examine previous electronic health records of SARS-CoV-2 patients to identify which chronic conditions are associated with in-hospital mortality in a nationally representative sample. Materials and Methods: The actual study is a cross-sectional analysis of SARS-CoV-2 infected patients who were treated in repurposed hospitals. The study includes a cohort of patients treated from 06-11-2020 to 15-03-2021 for COVID-19 associated pneumonia. To examine the presence of comorbidities, electronic health records were examined and analyzed. Results: A total of 1486 in-patients were treated in the specified period, out of which 1237 met the criteria for case. The median age of the sample was 65 years. The overall in-hospital mortality in the sample was 25.5%, while the median length of stay was 11 days. From whole sample, 16.0% of the patients did not have established diagnoses in their electronic records, while the most prevalent coexisting condition was arterial hypertension (62.7%), followed by diabetes mellitus (27.3%). The factors of age, male gender, and the number of diagnoses showed a statistically significant increase in odds ratio (OR) for in-hospital mortality. The presence of chronic kidney injury was associated with the highest increase of OR (by 3.37) for in-hospital mortality in our sample. Conclusion: The study reaffirms the findings that age, male gender, and the presence of comorbidities are associated with in-hospital mortality in COVID-19 treated and unvaccinated patients. Our study suggests that chronic kidney injury showed strongest association with the outcome, when adjusted for age, gender, and coexisting comorbidities.
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    Complication of ignored Foreign body in the respiratory tract
    (Macedonian Otorhinolaryngology society, 2022-06-01)
    Micevski, Goran
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    Kamsikovski, Igor
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    Complications of ignored foreign body in the respiratory tract Introduction: Foreign body aspiration is an emergency condition and may be fatal. Delayed diagnosis and treatment may be associated with complications. Objective: This study evaluated the association between complication of delayed treatment and complications during the procedure of extracting. Materials and methods: Foreign bodies are not normally found in the respiratory tract. The complications of delayed treatment could be: obstructive emphysema, atelectasis, tracheoesophageal fistula, bronchiectasis, haemoptysis, lung abscess, bronchopleural fistula, pneumonia, persistent coughing. Complications during treatment could be: coughing, dyspnoea, wheezing, stridor, haemoptysis, asphyxia, laryngeal oedema, pneumothorax, pneumomediastinitis, tracheobronchial rupture, cardiac arrest. The analysis is to be executed for the period 2016- 2021 year and the data for the survey were obtained from the records of the Department of Ear, Nose and Throat at the University Clinical Centre in Skopje. Results: All entities that can be aspirated, it can be said that organic, vegetal foreign bodies cause the biggest problems are the most dangerous and life treating conditions, given their unique nature and specific physical and chemical properties. Conclusion: A history of sudden-onset choking and cough, plus abnormal auscultation and radiological findings, are leading signs in the profile of foreign body aspiration. In these patients bronchoscopy is indicated. As time passes after aspiration the risk of complications is higher. The high prevalence of foreign bodies of vegetal origin is seen in children younger than 3 years of age.