Faculty of Medicine
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Item type:Publication, Transition Towards Transradial Approach Improves Outcomes of Acute Myocardial Infarction PCI(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2017-09-01); ; ; ;Antov, SlobodanKalpak, GjorgjiIntroduction and aim: Transradial (TRA) instead of transfemoral (TFA) approach strategy has been presented in research literature as superior access strategy especially for acute ST elevation myocardial infarction (STEMI) primary percutaneous coronary intervention (PCI). There is a paucity of registry-based data of outcomes from default TRA strategy compared to TFA. Materials and methods: All-comers STEMI PCI institutional Registry identified 1808 consecutive patients in time-frame of 40 months from 2007 to 2010, without making any exclusions. Moreover, we applied Propensity Score Matching (PSM) to replace randomization, address the potential confounding and selection bias. PSM derived 565 congruent pairs of patients from the groups. Results: After 30 days the primary composite endpoint of major adverse cardiovascular events (MACE) was in favor of TRA 6.5% vs. 12.4% in TFA group, simultaneously secondary endpoints of death in TRA with rate of 4.8% and with rate of 10.1% in TFA. Moreover, the rate of major access related bleeding was 1.1% in TRA vs. 8.5% in TFA, in contrast the major non-access related bleeding was 1.8% and 2.4% respectively showed no significant difference. One year Kaplan Meier survival plots were in favor of TRA. Conclusions: Default transradial access strategy is associated with improved STEMI PCI outcomes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The prevalence and outcomes of transradial percutaneous coronary intervention for acute coronary syndrome. Analysis from the single-centre ISACS-TC Registry (International Survey of Acute Coronary Syndrome in Transitional Countries) (2010-12)(Oxford University Press (OUP), 2014-01-01); ; ;Antov, Slobodan; The aims were to compare the prevalence and short-term outcomes of transradial (TRA) percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) in dedicated radial centre. This was a single-centre observational study of 3484 consecutively enrolled patients with ACS in a 3-year period (2010–12). There were 1648 patients with ST-elevation myocardial infarction (STEMI) and 1836 with non-ST-elevation ACS (NSTEACS). All patients underwent diagnostic coronary angiography within 24 h (STEMI) or within 72 h (NSTEACS). Percutaneous coronary intervention was performed in 84.9% patients (96.6% with STEMI and 74.9% with NSTEACS). Optimal medical treatment (OMT) only was recommended to 2.2% with STEMI and to 11.1% with NSTEACS. Coronary artery bypass graft (CABG) surgery was performed for 1.7% of STEMI and 14.1% of patients with NSTEACS (P < 0.0001). Most of the PCI procedures were performed through the wrist access (radial 97% and ulnar artery access 1.3%). There was high overall procedural success 98.5% (STEMI 99% and NSTEACS 97%). At 30 days, cardiovascular mortality was 4.7% in STEMI patients and 1.4% in patients with NSTEACS who were treated by PCI (P < 0.0001). Major adverse cardiac events defined as a composite of death, myocardial infarction, stroke, and non-CABG major bleeding and major access site complications at 30 days were higher in STEMI vs. NSTEACS patients (7.7 vs. 4.4%; P < 0.0001). Transradial access for PCI in a large cohort of unselected patients with ACS, is safe and feasible when performed by experienced radial operators. Patients with NSTEACS are more frequently treated with OMT and have higher referral rate to CABG in comparison with STEMI patients. There is higher 30 day mortality in patients with STEMI. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Single Center Registry of Percutaneous Ulnar Artery Approach for Coronary Intervention as an Alternative to TRA(American College of Cardiology, 2011); ;Antov, Slobodan; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Transulnar approach in STEMI patients: experiences from a single high volume center.(Oxford University Press (OUP), 2016-08-30) ;Vasilev, Ivan; ;Petkoska, Danica ;Antov, Slobodan - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Transradial carotid artery stenting in high risk patients(Oxford University Press (OUP), 2016-08-29) ;Petkoska, Danica; ;Antov, Slobodan ;Vasilev, Ivan - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Subclavian CTO stenting using Bilateral retrograde radial approach(Oxford University Press (OUP), 2016-08-01); ;Petkoska, Danica ;Antov, Slobodan ;Vasilev, Ivan - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Radial artery anomalies in the Macedonian population during transradial angiography procedures(Association of Medical Doctors "Sanamed" Novi Pazar, 2016); ;Petkoska, Danica ;Antov, Slobodan ;Vasilev, IvanJovkovski, Aleksandar - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Minimalistic Approach for Transcatheter Aortic Valve Implantation (TAVI): Open Vascular Vs. Fully Percutaneous Approach(Macedonian Academy of Sciences and Arts/ Walter de Gruyter GmbH, 2019-10-01); ; ; ;Antov, SlobodanNikolic, AleksandarAortic stenosis (AS) is the most common valvular heart disease in elderly people. Transcatheter aortic valve implantation (TAVI) has emerged as a revolutionary treatment for elderly patients with symptomatic severe aortic stenosis. The authors present the first experiences with transcatheter aortic valve implantation treatment in Macedonia and compare their findings in regard to differences between open vascular vs. minimalistic transfemoral TAVI approach. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Total wrist access for angiography and interventions: Procedural success and access site crossover in a high volume transradial center(Elsevier BV, 2018); ; ;Antov, Slobodan; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Transradial versus transfemoral access for female patients who underwent primary PCI in STEMI: Two years follow-up data from acute STEMI interventional registry(Elsevier BV, 2016-08); ;Sukmawan, Renan; ;Dharma, SuryaAntov, SlobodanFemale patients possess a higher risk for poorer outcome in ST segment elevation myocardial infarction (STEMI). There is possibility that transradial access (TRA) for primary percutaneous coronary intervention (PPCI) could provide better outcome than transfemoral access (TFA) in female patients with STEMI.
