Faculty of Medicine

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    Dellon Decompression Using WALANT: A Safe and Effective Approach for Patients with Peripheral Artery Disease
    (Multidisciplinary Digital Publishing Institute (Switzerland), 2025-02-12)
    Tusheva, Sofija
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    Jovanovska, Katerina
    Background: Wide-Awake Local Anesthesia No Tourniquet (WALANT) is revolutionizing surgery by providing a bloodless field without tourniquet use, reducing risks, costs, and enhancing patient comfort. While extensively used in hand surgery, its application in foot and ankle procedures, particularly for high-risk patients with diabetic neuropathy and peripheral artery disease (PAD), remains underexplored. This study evaluates the safety, efficacy, and outcomes of WALANT for tarsal tunnel decompression in such patients. Methods: Between March 2022 and April 2024, 32 patients with diabetic neuropathy and PAD underwent Dellon decompression of the tarsal tunnel. Five received spinal anesthesia with a tourniquet, while 27 underwent WALANT. Outcomes assessed included operative time, Visual Analogue Scale (VAS) pain scores, posterior tibial artery blood flow (via Doppler ultrasonography), and complications. Data were collected preoperatively, immediately postoperatively, and at six and nine months. Results: WALANT reduced operative time (40 ± 8 min vs. 65 ± 10 min) and required fewer personnel (four vs. six). VAS scores improved significantly in the WALANT group (from 8.65 ± 0.84 preoperatively to 1.21 ± 0.24 at nine months). Posterior tibial artery blood flow also showed superior improvements with WALANT (5.30 ± 0.65 cm3/s vs. 2.50 ± 0.45 cm3/s). Minor wound healing delays were noted in two WALANT cases; no major complications occurred. Conclusion: WALANT offers a safe, efficient alternative to spinal anesthesia for tarsal tunnel decompression in high-risk patients, minimizing ischemic risks, enhancing vascular outcomes, and reducing postoperative pain.
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    A challenging "silent depth" clinical scenario in North Macedonia: Unmasking a rare case of amelanotic melanoma with trapezius muscle invasion and metastatic disease
    (Centre for Evaluation in Education and Science (CEON/CEES), 2025)
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    Gjorgjeska, Andrijana
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    Ivanova, Maja
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    Aleksovski, Darko
    Introduction: Amelanotic melanoma is a subtype of melanoma that exhibits little or no pigment on visual or histological examination. Approximately 1-8% of all melanomas are amelanotic. It can mimic various benign or malignant melanocytic and non-melanocytic skin tumors, thereby presenting a significant diagnostic challenge. Primary amelanotic melanoma with muscle involvement is an extremely rare entity. A review of the literature revealed no series or case reports. Case Report: We present the case of a 62-yearold female patient with primary amelanotic melanoma infiltrating the trapezius muscle. The tumor was excised together with a clinically positive lymph node on the right side of the neck. Computed tomography (CT) angiography of the lungs, abdomen, and pelvis demonstrated bilateral diffuse nodular changes, a mediastinal pretracheal lymph node, and multiple diffuse liver lesions, consistent with secondary deposits. Molecular pathology revealed positivity for the BRAF V600E2/K/R/D mutation, and the patient began firstline targeted therapy with BRAF/MEK inhibition in accordance with protocols for BRAF-positive metastatic melanoma. Three months later, a follow-up CT scan demonstrated complete remission of the previously observed metastatic changes. Conclusion: Primary amelanotic melanoma with muscle involvement is exceptionally rare, with no published series or case reports identified. This case highlights the importance of early detection and treatment in suspected melanoma and underscores the need to consider melanoma in all clinically unclear cases.
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    IMPACT OF AWARENESS-RAISING CAMPAIGN ON PREVENTION OF PYROTECHNIC-RELATED HAND INJURIES IN NORTH MACEDONIA DURING CHRISTMAS HOLIDAYS
    (Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2023-04)
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    Kochoska, Renata
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    Aleksovski, Darko
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    Hadzitrifon, Sara
    Firecrackers and other pyrotechnic materials are used worldwide to celebrate national, religious, cultural festivals and holidays. In our country the use of firecrackers is usually during the holiday season, particularly during New Year's and Christmas days. The majority of users of firecrackers are adolescents who want to make the celebration more exciting, not being aware of the harmful effects and severe injures they can get by using pyrotechnics. The injuries caused by using pyrotechnics can vary from moderate such as first or second-degree burns to severe injuries like traumatic amputation of the fingers and hand, resulting in life-long mutilation. These injuries are expected to have long-term functional and psychological sequalae. Precisely because of that, our clinic started an awareness-raising campaign on prevention of pyrotechnic-hand injuries (PPH campaign) named "Don't let the firecrackers ruin your holidays”. The aim of this article is to present the impact of our PPH campaign in awareness raising against the use of pyrotechnic explosives and prevention of severe hand injuries by educating 15-16-year-old students about the dangers of using pyrotechnics and emphasizing the complexity of the hand and its importance in everyday life. In our study we used an anonymous questionnaire in order to see what was the impact of our presentation and discussions on students during the PPH campaign. From our 5-year experience with this type of campaign, we can see that awareness campaigns gave excellent results in decreasing the number of hand injuries. Therefore, our goal is this PPH awareness–raising campaign to be organized every year for generations to come.
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    SAVING A HAND WHILE FIGHTING THE TICKING CLOCK – A REPLANTATION STORY
    (2023-11)
    Aleksovski, Darko
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    Jovanovska, K.
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    Paget Schroetter syndrome
    (2023)
    Aleksovski, Darko
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    Hadjitrifon, Sara
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    Tusheva, Sofija
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    REVIVING CRANIAL OUTER TABLE PERFORATIONS AS A MODERN INNOVATION FOR COMPLEX SCALP AVULSION INJURIES RECONSTRUCTION: A CASE REPORT
    (Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2023)
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