Faculty of Medicine
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Item type:Publication, Visceral Leishmaniasis in the Republic of North Macedonia: A Retrospective Cohort Study(Galenos Yayinevi, 2025-11-11); ; Visceral leishmaniasis (VL) is a systemic protozoan vector-borne disease and represents the most severe clinical form of leishmaniasis, with fatal outcomes if left untreated. This study aimed to evaluate the key epidemiological, clinical, and laboratory findings, treatment options, and outcomes in patients with VL. Materials and Methods A retrospective analysis was conducted on the epidemiological and clinical characteristics of 84 patients diagnosed and treated for VL at the University Hospital for Infectious Diseases in Skopje, Republic of North Macedonia (RNM), between 2001 and 2023. Results The median age of patients was 47 years (range 1-74), with 77.4% being male. Contact with dogs was reported in 41.7% of cases. Seven percent of patients were immunosuppressed, and all were Human Immunodeficiency Virus-negative. The median time from symptom onset to diagnosis was 30 days (range 4-330 days). The predominant clinical manifestations were splenomegaly (97.6%), fever (96.4%), hepatomegaly (90.5%), and weight loss (54.8%). On admission, anemia, leukopenia, thrombocytopenia, and hypergammaglobulinemia were detected in 75%, 73.8%, 70.2%, and 63.1% of patients, respectively. A favorable outcome was achieved in 91.7% of cases; therapeutic failure occurred in 1.2%, and 7.1% of patients died. Conclusion VL should be considered a crucial differential diagnosis in patients from the RNM presenting with prolonged unexplained fever, splenomegaly, cytopenia, and hypergammaglobulinemia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hybrid peer-reviewed journals and publishing model: Bias or impartiality in editorial policy(Pensoft Publishers, 2025-03-24); ; Tsachev, IliaIn recent years, there has been a significant increase in scientific productivity—an increased number of published original articles, reviews, short communications, case reports, and letters to the editor. In this regard, there is a large number of peer-reviewed journals in all fields of scientific knowledge, including in the field of biomedical sciences. Many studies indicate the existence of so-called journal editorial board bias and acknowledge the difficulty of eliminating it. We present our brief opinion on an important topic such as how publishing policy in some peer-reviewed journals leads to feelings of bias and inequality among authors and how to address this. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Sellers of unpasteurized animal milk in unregulated markets: a key factor for human brucellosis control in El-Oued province, Algeria(African Field Epidemiology Network (AFENET), 2025); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FEVER OF UNKNOWN ORIGIN: CLINICAL CHARACTERISTICS AND ETIOLOGICAL SPECTRUM(Здружение на инфектолози на Република Македонија = Macedonian Society of Infectious Diseases, 2024-10-06); ; Objective: This study aimed to provide an overview of the etiological distribution, clinical features, and laboratory findings among patients with classic fever of unknown origin (FUO) admitted to the University Clinic for Infectious Diseases and Febrile Conditions in Skopje. Materials and Methods: All participants underwent a comprehensive medical history review, physical examination, and predetermined laboratory investigations. The final diagnosis was established using specific diagnostic procedures guided by potential diagnostic clues (PDCs). After diagnosis, patients were categorized into infectious and non-infectious FUO groups. Results: The analysis included 47 participants, with a mean age of 57 years, the majority of whom were male. Fever lasted an average of 30 days, with a median temperature of 39 °C. Infections accounted for 53.2% of cases, followed by inflammatory non-infectious diseases (25.5%), malignancies, and other miscellaneous conditions (10.6%). The most frequent symptoms were myalgia, arthralgia, fever, sweating, and malaise. On physical examination, hepatosplenomegaly, heart murmurs, joint swelling, and skin rashes were the predominant findings. Significant laboratory abnormalities included elevated ferritin and procalcitonin levels across groups. Conclusion: Specific variations in clinical presentation and laboratory findings may help facilitate a more rapid differential diagnosis of classic FUO. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, METABOLIC SYNDROME IN ANTIRETROVIRAL THERAPY TREATMENT EXPERIENCED BY PEOPLE LIVING WITH HIV(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2024); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical characteristics of human brucellosis in different age groups in the Republic of North Macedonia-A case series(Springer Science and Business Media LLC, 2024-12-04); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Фундаменталното значење на анамнезата во дијагностичкиот протокол кај пациент со треска од непознато потекло(МАКЕДОНСКА МЕДИЦИНСКА СТУДЕНТСКА АСОЦИЈАЦИЈА, 2023-12-16); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, SAFETY AND EFFECTIVENESS OF DIRECT-ACTING ANTIVIRALS IN PATIENTS WITH CHRONIC HEPATITIS C AND CHRONIC KIDNEY DISEASE(Macedonian Infectious Diseases Society, 2022-11); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical experience in the treatment of flu patients with Oseltamivir during the interpandemic period(National Center of Infectious and Parasitic Diseases, 2002-11); ; Toshevski, Boban - Some of the metrics are blocked by yourconsent settings
Item type:Publication, EFFICACY AND SAFETY OF THE NEURAMINIDASE INHIBITOR OSELTAMIVIR IN THE TREATMENT OF INFLUENZA INFECTIONS IN ADULTS(2002-10);