Faculty of Medicine
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Item type:Publication, OUR EXPERIENCE FROM THE THERAPY OF THE CHEMICAL INJURED EYE(SOE, 1995) ;Antova Velevska M. ;Popovski T.; Arnaudovski Z.Chemical burns of the eye present a continuing therapeutic challenge from the initial injury to the final attempts at restoration of vision. Some immunologic resources of the corneal cellular immunity were carried in the dynamic of the clinical stage. The authors obtained significant success in treatment of the alkali burns by application of various nonspecific and specific medicaments (ascorbate, corticosteroids and collagenase inhibitors). - Some of the metrics are blocked by yourconsent settings
Item type:Publication, LONG TERM RESULTS OF KERATOPLASTY(SOE, 1995) ;Popovski T. ;Antova M.; Arnaudovski Z.ln this study the authors present their experience of the op. treatment of the keratoconus with the keratoplasty in the Ophthalmology Clinic of the University Sent Cyril and Methody in Skopje in the period of 1973-1993.They confirm that the keratoplasty-partial thickness (lamellar) preserving the Descemet's membrane of the recipient cornea. The authors used op. technique which is preserving the integrity of the camera anterior i.e. the surgery of the close eye. After the treatment of the keratoconus with the partial thickness (lamellar) they succeed in satisfying anatomically and functional results. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Drainage or not, of subretinal fluid in conventional retinal detachment surgery(SOE, 1999) ;Josifova Т. ;Ivanovska М. ;Blazevska К.; Gavrilovska M.Aims: To show whether the drainage of subretinal fluid, has or hasn't got the advantage in the conventional retinal detachment surgery. Material and methods: We have analyzed 82 patients with total or subtotal rhegmatogenous retinal detachment with deep subretinal fluid. They underwent buckling procedure with silastic sponge explants and encircling bands, with drainage of subretinal fluid during the operation. While performing the operation we have also injected a balanced salt solution 1-2ml, or air into the vitreous. Results: After the first operation out of all patients reattachment was achieved in 73 patients (89,1%). Retinal reattachment with complete resorbed subretinal fluid and accurate sitting of the brakes on the buckles was seen in 52 patients (63%) in the first post-operative day, after 2-4 days in 7 patients (8.53%), after 5 to 7 days in 3 patients (3,65%), and after 15 days in 1 patient (1,21%). As a complication of the drainage procedure in 6 patients (7,3%) we have noticed vitreal haemorrhage, as well as retinal haemorrhage in 2 patients (2,4%). Conclusion: The advantages and disadvantages in the performing of the drainage procedure during the conventional retinal detachment surgery lead to different opinions whether to perform it or not, and it makes this issue an open question. A long term study with groups under similar conditions, especially in cases with macula detachment, deep subretinal fluid and extensive periretinal membranes perhaps will give us the answer. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, RETROBULBAR NEURITIS - THE MOST FREQUENT MANIFESTATION OF MULTIPLE SCLEROSIS(1995) ;Sazdovska M. ;Dzajkova E.D; ; Icevska LIn order to determine the representation of retrobulbar neuritis in the neuroophthalmological pathology and their possible connection with retrobulbar neuritis, hospitalized patients with the diagnosis multiple sclerosis were treated within the period of 5 years (1990-1994). From the total number of neuroophthalmological disorders treated at the Clinic within the studied period, retrobulbar neuritis was found in 30 patients (34,3%). The retrobulbar neuritis is an inflammation of the optic nerve which process starts in the back of lamina cribrosa. In most cases it attacks the population between 20 - 40: years of age. The clinical picture is characterized by a large decrease of visual acuity, the existence of central scotoma within the visual field, whereas the finding at the fundus remains unchanged. Visual acuity, visual field and the condition of the visual evoked potentials have been followed. On the basis of the following parameters and the positive neurologic findings, 15 cases (50%) were suspected of having multiple sclerosis. Multiple sclerosis was confirmed in 3 of the cases (10%) with retrobulbar re lapse. Тhe pathological findings of VEP was presented in 15 cases (50%) whereas the characteristically findings of the visual field was found in 13 cases (43,3%). The fact that the retrobulbar neuritis appear as a monosymptom of multiple sclerosis has been suggested by the last several years, following the patients with this disorder. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Увеити кај деца(1999); ;Ивановска М. ;Иванова Г.Икономова Л.Вовед: Одредени увеални ентитети се авуваат кај деца и истите не се така чести ка] другата возрасна група - постари пациенти. Диференциіална диіагноза на увеитите кај децата е почесто јасно дефинирана (75%), наспроти 50% кај возрасните пациенти. Цел: Да се оредат најчестите увеални ентитети според анатомската поделба на увеитите прифатена од Светската група на увеолози и да се одредат најчесто диагностицираните увеити ка деца. Материал и метод: Студиата опфака по 52 пациенти од 2 групи на возрасни пациенти и деца во период од 2 години. Резултати: Јувенилен реуматоиден артритис е начесто етиолошки диагностициран ка предните увеити ка деца (25%). Предните увеити ка деца се 35% од сите увеити. Интермедиален увеит е застапен ка 16-22% од сите увеити ка деца. Токсоплазмозата е наічеста причина за заден увеит. Од сите увеити ка деца 10% отпаґа на токсоплазмозата. Дифузниот увеит не е толку чест ка децата. То може да е знак на Морбус Бехцет, Вогт- Коанаги-Харада синдром, саркоидоза или да претставува природна еволуциа на увеитот. Заклучок: Предниот увеит е назчест 35%, но токсоплазмозата како увеален ентотет е начеста во нашата возрасна група (10%). - Some of the metrics are blocked by yourconsent settings
Item type:Publication, РИЗИК ОД ПОСТОПЕРАТИВНИ ИНФЕКЦИИ (ПОИ) ПРИ ЕКСТРАКАПСУЛАРНА ЕКСТРАКЦИА НА КАТАРАКТА(1999) ;Ивановска М. ;Јосифова Т.Цел на трудот: Анализиран е ризикот од ПОЙ каі пациенти со екстракапсуларна екстракциа на катаракта (ЕЦЦЕ) со интраокуларна имплантациа на лека (ИОЛ) опериорани за 3 г. Материал и методи: На 360 болни (40-76 год.) со ЕЦЦЕ изведена по стандарден протокол со операционен микроскоп, со Годеров систем за аспирациа и иригациа и имплантациа на соодветна ИОЛ (АЛКОН и Фармациа Упон). Предоперативно правени се интернистички и лабораториски иследувана и 24 ч. се лекувани со локална антибиотска терапиа (ЛАТ). Постоперативно се следени со биомикроскоп и лекувани 3 м. со ЛАТ и кортикостероиди. Резултати: ПОЙ се изразуваа со клиничка слика на преден увеит (ПУ) ко е утврден ка 9 (2,5%) пациенти. Како рана комликациа се ави по 5-8 постоперативни дена ка 3 болни: 2 со ревматоиден артритис (РА) 1 со диабетес мелитус (ДМ). Како касна компликациа се ави по 1-3 месеци ка 6 пациенти: 1 со акутен инфаркт, 4 со ДМ и диабетична ретинопатиа (ДР), 2 со хроничен РА и 2 со РА ко нередовно земал терапиа. Заклучок: Ризикот од ПОИ ка ЕЦЦЕ со ИОЛ, иако минимален е присутен ка пациенти со ДМ со ДР, хроничен РА и кардиоваскуларни болести. Потребна добра предоперативна подготовка и стабилии параметри во однос на придружната болест, како и добро постоперативно следене на оперираното око. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, БАКТЕРИСКА ЕТИОЛОГИjА И ПРЕДИСПОНИРАЧКИ ФАКТОРИ KAJ КОРНЕАЛЕН УЛКУС(1997); ; ; Цел на студиата е ретро-проспективно да се анализира бактериолошкиот наод ка брисеви од око на пациенти со корнеален улкус и да се испитаат факторите на ризик за негова поава. Испитани се 44 пациенти лекувани на Очна клиника, Клинички центар, Скопје во периодот јануари 1994 г. до крајот на 1996 г. Откриени се бројни етиолошки (фактори на ризик (sad) (1) Егзогени фактори: траума 12 случаи (сл.) (16%), контактни леки 3 сл. (6%) и тоа: 2 сл. (4%) меки контактни леки и 1 сл. (2%) тврди контактни леки. Pseudomonas aeruginosa беше изолиран ка 2 сл. (4%). (2) Дисфункциа на очните аднекси: трихиаза со и без ендтропиум 2 сл. (4%), каналикулитис/дакриоциститис 3сл. (6%), егзофталмус при дисфункциа на тиреоидна жлезда 1 сл. (2%). (3) После екстракциа на катаракта - 3 сл. (6%), каде што начесто по 6 месеци се подавил корнеален улкус. (4) Системски заболувана: диабетес мелитус 8 сл. (18%), атопичен дерматит/ блефароко-нунктивит 3 сл. (6%), крвни заболувана 2 сл. (4%). (5) Употреба на системска и локална терапиа: имуно-супресивна (кортикостероиди, антивирусни лекови и цитостатици) 3 сл. (6%), антибиотици 1 сл. (2%). Средна возраст на пациенти 62 години. Од вкупно 44 примероци 30 (66%) беа позитивни. Ка 11 сл. (36%) е изолиран Staphylococcus koagulaza negativen, kaj 7 сл. (23%) Streptococcus pneumoniae, Staphylococcus aureus. Kaj 6 c. (20%), Pseudomonas aeruginosa 5 сл. (16%) и Moraxella spp. кaj 1 сл. (3%). Вонашите случаи најчест бактериолошки наод беше Staphylococcus koagulaza negativen 36%, а како начест етиолошки фактор е траумата 16% и диабетес мелитус 18%. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ACANTAMOEBA KERATITIS-a case report(Ophthalmological Society of Northern Greece, 1998); ;Antova Velevska M.Bron A.Acanthamoeba keratitis still is a problem in ophthalmology because of diagnostic and therapeutic difficulties. To date, Acanthamoeba keratitis is an increasing pathology because of the more widespread use of the contact lenses. The patient was 22 year old myopic student, soft lens wearer. He complained of progressive pain and redness in his left eye since a week. The patient was unsuccessfully treated with topical antibiotics and steroids, including antiviral and antihistamininics. After three months, he complained redness and photophobia with comeal ulcer and Acantamoeba keratitis was suspected. Methods :the essential parasitological diagnosis was confirmed after comeal scarping inoculation onto agar with lown of Eschericia coli and morphological identification and according to the Pussard and Pons classification were done .A therapy with 0,02 PHMB for three months with prolonged decreasing dosage has begun with resolution of the infection. Conclusion: success factor for diagnosis and therapy are early identification of the parasite and the use of intensive therapy with 0,02%PHMB for considerable period of time. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, EXPERIENCE FROM THE THREATMENT OF KERATITIS HERPETICA(1996); POPOVSKI T.In the period of 5 years, the authors have healed a group of 40 patients with keratitis herpetica using the known antiviral therapy on 20 patients with keratitis herpetica profunda, compared with the surgical treatment (debridment) combined with antiviral therapy on 20 patients with keratitis herpetica superficialis. By removing of the pathological substrate, reepithelization of the cornea with the healthy epitelium is accelerated in the superficial keratitis herpetica. In other forms of keratitis herpetica the antiviral treatment with a proper dosage takes dominant place. Conclusion: The patients were controlled in the period of 5 years, in which, in 20 cases of keratitis profunda, 45 %, that is 9 of them, had relapses twice. In patients with superficial forms, who were threated with debridment and antiviral therapy; there were no relapses Although the debridment is rather old-fashioned invasive therapy, we consider that it is applicable in superficial forms of keratitis herpetica together with antiviral therapy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CRYOGLOBULINS IN UVEITIS(SOE 1995, 1995) ;Bosnjakovska S. ;Polenakovic B.; Arnaudovski Z.The authors examined cryoglobulins in a group of patients with anterior uveils and in a group of patients with posterior uveitis by means of a prospective study. Total cryoglobulins were measured by the method of Lowry - identification of cryoglobulins with oucherlony, Scheidegger and the quantity of the elements of cryoglobulins with the method of Mancini. The authors exam the activity of antigamma globulins with Reuma factor. The purpose of our examination is determination of the cryoglobulin levels in the uveilis with the different aethiology and correlation between the level of the cryoglobulins only as separate form of the illness.
