Faculty of Medicine
Permanent URI for this communityhttps://repository.ukim.mk/handle/20.500.12188/14
Browse
3 results
Search Results
- Some of the metrics are blocked by yourconsent settings
Item type:Publication, INFORMED CONSENT IN GENETIC REASEARCH(Macedonian Association of Anatomists and Morphologists, 2023); ; ; ; Recognizing the ethical, legal, and social implications (ELSI) of genetic testing becomes crucial for physicians in the face of complex medical issues, as they are increasingly expected to counsel their patients regarding the medical, psychological, and social responses arising from genetic information. Genetic medicine, with its extreme complexity and the potential repercussions on an individual's life, raises important questions in the ethical, deontological, and legal realms of medicine, playing a primary role in personalized medicine. The aim of this paper is to underscore the significance of informed consent and to provide insights into the ethical procedures associated with genetic testing. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ETHICAL ASPECTS IN CLINICAL TRIALS IN CHILDREN(Македонско лекарско друштво = Macedonian Medical Association, 2021); ; ; Conducting clinical trials in children has particular importance as they strive to provide optimal care and therapy for this specific group of patients, but their implementation is still complex. This is often due to the lack of agreed-upon research objectives, unresolved questions about informed consent, and the general perception that children are a vulnerable group of subjects. For providing the best clinical care for pediatric subjects, it is important to conduct careful, effective research that has a scientific basis to answer important clinical questions. The main challenge of pediatric research is the risk and therefore the question arises whether the purpose of the research justifies the risks associated with the study? The four ethical principles should serve as a framework in the process of conducting clinical trials in children: benefacere, justice, respect for personality and confidentiality. One principle is no more or less important than the others, so all four must be taken into account when conducting a research. The ethical principle of "respect for personality" is the basis for the process of informed consent. It is a legal document by which the patient voluntarily agrees to participate in a research. The informed consent must be signed by child's legal guardian(s) and this step cannot be delegated to other family members or friends unless there is a legal basis. However, with proper planning and monitoring the study process, a research can be conducted in children even though they are considered as a vulnerable population. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, THE PRACTICAL AND ETHICAL CHALLENGES OF CONDUCTING RESEARCH WITH CHILDREN AND ADOLESCENTS(2009); Uljarević MirkoDue to its noninvasive nature, good spatial resolution and other advantages functional magnetic resonance imaging (fMRI) has become a tool of choice for investigating the brain mechanisms underlying psychological phenomena. Functional MRI studies have elicted substantial media coverage and this has led to increased public interest in neuroimaging. Having in mind enormous potential of this method as well as potential risks it is of crucial importance to be aware of ethical and practical challenges when conducting fMRI research, especially with children and adolescents. In this essay we selectively review issues regarding informed consent and child’s capacity to withdraw from the study, importance of incidental findings and the problem of motion during image acquisition. Strategies how to deal with those problems are also addressed.