Faculty of Medicine
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Item type:Publication, Extranodal Diffuse Large B-Cell Lymphoma of the Small Bowel in Female Patient Causing Intestinal Obstruction: A Case Report(Vilnius University Press, 2022-12-30); ; ; Diffuse large B cell lymphoma is the most common extranodal non-Hodgkin lymphoma of the small intestine accounting for more than 50% of cases. Forty percent of these cases initially present with small bowel obstruction. Therefore, the diagnosis is usually established after surgery for bowel obstruction. The treatment is then continued with a certain chemotherapy regimens. We present a case of a 46-years-old female patient with signs of small bowel obstruction due to previously undiagnosed diffuse large B-cell lymphoma. Postoperatively, the patient was treated with 7 cycles of R-CHOP protocol and complete response was achieved in the short follow-up period.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, INEFFECTIVE ERYTHROPOIESIS IN PATIENT WITH BETA THALASSEMIA AND MYELODYSPLASTIC SYNDROME CASE REPORT(Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, 2024); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, FIRST-LINE IMMUNOCHEMOTHERAPY FOR FOLLICULAR LYMPHOMA PATIENTS- SINGLE CENTER EXPERIENCE(Macedonian Association of Anatomists, 2024); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, CLL-393 Outcomes of COVID-19 Infections in Patients With Hematological Malignancies in Republic of North Macedonia(Elsevier BV, 2022-10); ; Labachevska, Marija Popova - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Scrofuloderma- a rare but serious diagnostic challenge(Македонско лекарско друштво = Macedonian medical association/De Gruyter, 2024-04); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Flag-IDA regimen as salvage chemotherapy before haematopoetic stem cell transplantation in the treatment of refractory/relapsed acute myeloblastic leukaemia: single-centre experience(2011); ; ; ; Dukovski, DushkoDuring the past several decades, improvements in chemotherapeutic regimens and supportive care have resulted in signifi cant but modest progress in treating AML.Conventional chemotherapy is highly effective in the treatment of acute myeloblastic leukemia (AML). About 50-80% of adult patients with de novo acute myeloblastic leukemia achieve complete remission (CR) with currently available chemotherapy regimens consisting of antracyclines and cytarabine. However, relapse develops in more that 40% of the cases within two years, and 15-25% of patients fail to achieve complete remission because resistant to treatment or death. The management of cases with primary refractory and /or relapse disease is very diffi cult and prognosis in this subset of patients after several different chemotherapy combinations is still very poor with a CR rate 33-41%. We evaluated effi cacy and toxicity profi les of FLAG-Ida combination chemotherapy as salvage chemotherapy before hematopoietic stem cell transplantation in patients with refractory/ relapsed AML. At the University Hematology Clinic in Skopje, Macedonia, in the period 2006-2009, twenty patients with refractory/relapsed acute myeloblastic leukemia were treated with FLAG-Ida regiment. Patients were between 16-52 years old, 6 female and 14 male. They were treated with fl udarabine 30 mg/m2, cytosine arabinoside (AraC) 2 g/m2 for 5 days, Idarubicin 10 mg/m2 for 3 days, and granulocyte colony stimulating factor G-CSF 5 mikrog/kg from day 0 till neutrofi l recovery (ANC >1.0 x109/l). Complete remission were achieved in 9 patients (45%), four patients (25%) died of post chemotherapy complications, and 7 failed to achieve complete remission. Out of 9 patients who achieved complete remission, 4 went autologous bone marrow transplantation, 4 went allogeneic bone marrow transplantation, and 1 is being evaluated for the same. Major complication encountered were mucosistis, transient hepatic toxicity, fungal and bacterial infections. Our experience confi rmed that FLAG-IDA regimen is well tolerated and effective therapy in relapsed/refractory acute myeloid leukemia. FLAG-Ida is a good choice in cases with refractory/relapsed acute myeloblastic leukemia for salvage chemotherapy and it is wise to consolidate it with hematopoietic stem cell transplantation. Those patients included in the hematopoietic progenitor transplant program, clearly benefi t from allogeneic or autologous BMT, obtaining a longer disease free survival and overall survival. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 10-year experience in the treatment of multiple myeloma with autologous stem cell transplantation(2011); ; ; - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Extranodal Diffuse Large B-Cell Lymphoma of the Small Bowel in Female Patient Causing Intestinal Obstruction: A Case Report(Vilnius University Press, 2022-12-30); ; ; Diffuse large B cell lymphoma is the most common extranodal non-Hodgkin lymphoma of the small intestine accounting for more than 50% of cases. Forty percent of these cases initially present with small bowel obstruction. Therefore, the diagnosis is usually established after surgery for bowel obstruction. The treatment is then continued with a certain chemotherapy regimens. We present a case of a 46-years-old female patient with signs of small bowel obstruction due to previously undiagnosed diffuse large B-cell lymphoma. Postoperatively, the patient was treated with 7 cycles of R-CHOP protocol and complete response was achieved in the short follow-up period.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Histological and immunohistochemichemical study of malignant lymphomas in Macedonia - Study of 222 cases(Macedonian Association of Pathology, 2013); ; ;