Faculty of Medicine
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Item type:Publication, P158 Fungal airway colonisation in cystic fibrosis patients in the Institute for Respiratory Diseases in Children - Skopje, Republic of North Macedonia(Elsevier BV, 2021); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, P167 Prevalence of liver disease in cystic fibrosis patients in the Institute for Respiratory Diseases in Children - Skopje, Republic of North Macedonia(Elsevier BV, 2021); ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Refractory anemia as a first major sign of Neuroblastoma in 8 months old infant(Frontiers Media SA, 2021); ; Chakalaroska, Irena - Some of the metrics are blocked by yourconsent settings
Item type:Publication, AMYAND’S HERNIA–A RARE CASE OF RIGHT-SIDED INGUINAL HERNIA(Macedonian Association of Anatomists and Morphologists, 2023); Amyand’s hernia is the presence of the appendix in the inguinal hernia sac. The prevalence of this type of inguinal hernia is about 1%. Majority of cases of Amyand’s hernia are incidentally diagnosed during surgical treatment of inguinal hernia. Amyand’s hernia typically presents on the right side since right-sided inguinal hernia is more common and the appendix is located in the lower right quadrant of the abdomen. We present a case of a 23-year-old patient hospitalized at the University Clinic for Digestive Surgery in Skopje for elective surgical treatment of right-sided inguinal hernia. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ETHICAL ASPECTS IN CLINICAL TRIALS IN CHILDREN(Македонско лекарско друштво = Macedonian Medical Association, 2021); ; ; Conducting clinical trials in children has particular importance as they strive to provide optimal care and therapy for this specific group of patients, but their implementation is still complex. This is often due to the lack of agreed-upon research objectives, unresolved questions about informed consent, and the general perception that children are a vulnerable group of subjects. For providing the best clinical care for pediatric subjects, it is important to conduct careful, effective research that has a scientific basis to answer important clinical questions. The main challenge of pediatric research is the risk and therefore the question arises whether the purpose of the research justifies the risks associated with the study? The four ethical principles should serve as a framework in the process of conducting clinical trials in children: benefacere, justice, respect for personality and confidentiality. One principle is no more or less important than the others, so all four must be taken into account when conducting a research. The ethical principle of "respect for personality" is the basis for the process of informed consent. It is a legal document by which the patient voluntarily agrees to participate in a research. The informed consent must be signed by child's legal guardian(s) and this step cannot be delegated to other family members or friends unless there is a legal basis. However, with proper planning and monitoring the study process, a research can be conducted in children even though they are considered as a vulnerable population.