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Title: | Effect of simvastatin in apolipoprotein E deficient mice with surgically induced chronic renal failure | Authors: | Ivanovski, Ognen Szumilak, Dorota Nguyen-Khoa, Thao Nikolov, Igor G Joki, Nobuhiko Mothu, Nadya Maizel, Julien Westenfeld, Ralf Ketteler, Marcus Lacour, Bernard Drüeke, Tilman B Massy, Ziad A |
Issue Date: | Apr-2008 | Publisher: | Ovid Technologies (Wolters Kluwer Health) | Journal: | The Journal of urology | Abstract: | Patients with a surgically reduced renal mass are at increased risk for progressive renal failure, which often requires renal replacement therapy or kidney transplantation. We investigated the effects of simvastatin supplementation on uremia enhanced atherosclerosis and vascular calcification in apoE(-/-) (apolipoprotein E deficient) mice (Charles Rivers Laboratories, Wilmington, Massachusetts) with or without superimposed chronic kidney disease. | URI: | http://hdl.handle.net/20.500.12188/9601 | DOI: | 10.1016/j.juro.2007.11.042 |
Appears in Collections: | Faculty of Medicine: Journal Articles |
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