Vela Ilir
Preferred name
Vela Ilir
Official Name
Vela Ilir
Translated Name
Vela Ilir
Alternative Name
Vela I
Vela I,
I.Vela
I Vela
I Vela.
Ilir V
Ilir,Vela
Ilir Vela
Vela, Ilir
Email
ilir.vela@medf.ukim.edu.mk
10 results
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Item type:Publication, Evaluation of Total Thyroidectomy for Treatment of Benign Diseases of Thyroid Gland(Scientific foundation SPIROSKI, 2020-04-25); ;Tolevska, Natasha ;Qafjani, Ardit; BACKGROUND: The controversy of using total thyroidectomy (TT) in treatment of benign thyroid diseases still remains controversial over the rates of complication, mostly recurrence nerve palsy and hypocalcemia, compared to non-total thyroidectomies. The latest reports in this field of research showed that that the number of complications of TT is decreasing as the skills of surgeons increase. AIM: In this study, we reviewed 209 cases of total thyroidectomies for benign thyroid diseases where such surgery was indicated. The results were evaluated whether they support the previous reports that TT is save method of treatment of diffuse multinodular goiters, Graves’ disease thyroid adenomas with diffuse goiters and thyroiditis. METHODS: Two hundred and nine patients, 36 males and 173 females, medium age 47 (17–77) operated with TT between 2016 and 2018 were included in the evaluation study. We evaluated the: Diagnosis, indications for operation, pre-operative medication administration, laryngeal recurrent nerve palsy, hypocalcemia, hypoparathyroidism, and patohistology findings. The follow-up for hypocalcemia and laryngeal nerve palsy was performed 1 year postoperatively. RESULTS: The age of the patients was between 17 and 77 years, medium-range 47 years old. Of 209 patients, 173 (83%) were female and 36 (17%) male with a gender ratio of 1:4.8 males to females. Diagnoses before surgery were established as follows: Multinodular euthyroid goiter (MNEG) n = 106 (48.80%), multinodular toxic goiter n = 12 (5.74%), Graves’s disease n = 6 (2.87%), adenoma with multinodular goiter n = 73 (34.92%), and n = 16 (7.65%) patients with thyroiditis. Recurrence laryngeal nerve palsy (RLNP) occurred in 6 patients (2.87%), temporary within 3 months after the operation in 4 patients (1.92%) and permanent palsy within 6 months and more after an operation in 2 patients (0.95%). Voice hoarseness immediately and within 1 month after the operation was registered in 32 patients (15.3%). RLNP and hoarseness were registered mostly in patients with pre-operative problems, mostly with extra big MNEG. One of the permanent injuries of RLN was bilateral and all others were one sided. All patients were operated with normal pre-operative vocal cord movement findings. Post-operative hypocalcemia was registered in 35 patients (16.74%). Temporary nonsignificant hypocalcemia in 10 (4.78%), temporary significant hypocalcemia in 17 (8.13%), temporary severe hypocalcemia in 6 patients (2.87%), and permanent hypocalcemia in 2 patients (0.95%). CONCLUSION: Many studies have shown that the rate of complications is almost even for TT and NTT done for benign and malignant diseases of thyroid gland. Our data have shown that the risk of post-operative complications with TT is proportional to the number of complicated pre-operative findings of benign thyroid glands. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Identification of the potential protein biomarkers in papillary thyroid carcinoma(SHMSHM/AAMD, 2021); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Thymectomy for myasthenia gravis and anesthetic implications - a retrospective study(League Against Epilepsy of the Republic of Macedonia = Лига против епилепсија на Република Македонија, 2017); ; ; ; Mojsova Maja - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Solitary metastatic deposit in the mandible from follicular thyroid carcinoma(2020-07-01); ; ; ; Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid, after papillary carcinoma. Oral metastasis arising from FTC is very rare. Mandible is more commonly affected than maxilla, with the premolar-molar region being the most frequent site of metastasis. We present the case of a 68yearold female, with swelling in the region of the parotid gland, complaining of periodic rightsided pain in the temporomandibular joint, which occurred most often in the morning with numbness and pain, and difficulty in opening the mouth. After ultrasound and X-ray, the patient was operated and the pathohistological finding was in favor of metastasis of FTC. After 3 months, a total thyroidectomy was performed, and FTC was detected in the right thyroid lobe. Laboratory results were as follows: FT4 = 9.92 pmol/L, thyroid-stimulating hormone = 9.9 mIU/L, and hTG >300 μg/L. Bone scan showed no bone metastasis. Radioablation with 131I of 150 mCi was given to the patient, followed by substitutional therapy with levothyroxine. Mandible metastasis as a single skeletal deposit from follicular thyroid carcinomas is a rare clinical finding. Maxillofacial surgeons should consider and rule out thyroid pathology before performing operation of tumor formation in the mandible region. If feasible, surgical-based treatment options offer the best survival outcomes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, PNEUMOTHORAX TREATMENT IN PATIENTS WITH EMPHYSEMATOUS LUNGi DISEASE WITH TWO DIFFERENT TECHNIQUES.("Ss Cyril and Methodius"University, Faculty of Medicine, Skopje, R. N. Macedonia, Department of Anesthesia and Reanimation, 2017) ;Jakupi N; ;Dzikovski I; Maric NObjective: to compare the outcomes of thoracotomy and video-assisted thoracoscopic sur- gery (VATS) in the treatment of pneumothorax in patients with emphysematous lung disease. Заклучок: Според освртот врз литературата јасно е дека ларингоскопијата и интубацијата може да предизвикаат хемодинамиска нестабилност со појава на неспецифични варијации во ST-T сегментот. Тоа е несакан сучај на кој секогаш треба да се мисли, особено кај хипертензивните пациенти кои се третирани со RAS антагонистите, кои предизвикуваат значаен пад на артерискиот крвен притисок, кој е пак одговорен за коронарната вазоконстрикција и промените во големината на ST сегментот. Главните промени се случуваат 5 минути по интубацијата. Method and Material: in prospective study we analyzed the level of postoperative compli- cations, duration of drain presence, total drain collection, site infections, length of hospital stay (LOHS) and recurrence of pneumothorax in two groups of patients. Group OT (n=12) included patients undergoing open thoracotomy and group VATS (n=12) underwent VATS for primary pneumothorax treatment. | 26 | Number 3. December 2017 | 27 | ABsTrACT results: Demographic data between the groups was homogenous. Duration of drain presence was 4.08 vs. 3.8 days in respect to the groups. Statistically significant large amount of drain collection was found in the OT group (604.1 ml vs. 391 ml). Length of hospital stay was statis- tically longer in group OT (p=0.02). Two patients had recurrent pneumothorax in VATS group. Conclusion: According to our study patients, who undergo VATS, postoperatively have lower amount of drain collections, have drain presence for less days, have less days spent in the hospital, but have increased recurrence rate. Even though our study has small number of patients included, it opens a door to larger study to confirm the results. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, KI67 EXPRESSION IN PAPILLARY THYROID CANCER(SHMSHM / AAMD, 2021-04-01); ; ; ; Ridvan BajramiPapillary thyroid cancer is the most common thyroid cancer and accounts for over 70% of malignant thyroid diseases. In the last few decades the incidence of the papillary thyroid cancer (PTC) has increased worldwide. The aim of the study is to evaluate the Ki67 protein expression in papillary thyroid carcinoma and to correlate with clinicopathological parameters (age, gender, tumor size, vascular invasion, capsule invasion, lymph node metastasis, multifocality). Materials and methods. The study population consists of 47 patients diagnosed with PTC, and benign thyroid changes. After standard surgical procedure formalin fixed paraffin embedded (FFPE) tissue sections for standard histological and immunohistochemically Ki67 analysis were obtained. Results. Out of 47 patients, 24 (51.06%) were diagnosed with papillary thyroid cancer (Ki67expression varies in the range 8.58-5.76%) and 23 (48.94%) were benign changes of the thyroid gland (expression of Ki67 varies in the range 1.61±1.23%). For Z = 5.49 and p <0.001 (p = 0.000) the cancers had significantly higher Ki67 expression than benign tumors. There was no significant variation in Ki67 expression in papillary thyroid carcinoma in comparison to cervical lymph node metastases and tumor position. These parameters vary with tumor size and multifocality. Conclusion. Ki67 is an appropriate biomarker used to distinguish papillary carcinoma from benign thyroid lesions. Ki67 expression was associated with tumor size and multifocality. High expression of Ki67 could be an important indicator for assessing the clinical course and prognosis of the disease itself. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Video-assisted thoracic surgery (VATS) right lower lobectomy after neoadjuvant treatment – case report(2022-01-10); ;Nexhati JakupiDzikovksi IgorLung cancer is the most common cause of cancer-related death in men and second-most common in women. While surgical resection offers the best chance of curing those with early-stage lung cancer, the traditional open-chest approach (called a thoracotomy) typically requires five to seven days of recovery in the hospital, with an extended recovery at home. Over the past two decades, video-assisted thoracic surgery (VATS) has revolutionized how thoracic surgeons diagnose and treat lung diseases. This video-assisted thoracic surgery (VATS) technique reduces a patient's hospital stay to about three to four days, and the patient experiences a more rapid recovery with less pain after VATS lobectomy surgery as compared with the traditional thoracotomy approach. We report a VATS right lower lobectomy case in a 65-year-old patient with post neoadjuvant therapy for adenocarcinoma. With pre-surgical tests, which include: a complete physical exam, CT scan, PET scan, bronchoscopy, blood test, electrocardiogram and spirometry. The patient was proposed for two-portal thoracoscopic surgery. The patient was placed in a left lateral decubitus position, and a double incision was performed at the anterior level of the 5th intercostal space (4 cm incision) and the second one at the level of the 8th intercostal space (2 cm incision). A right lower lobectomy with a two-portal technique was successfully performed. The postoperative course was without complications, and the patient was discharged home on the 4th postoperative day. The two-portal video-assisted thoracoscopic surgery (VATS) approach is an excellent option for lung cancer management, offering a quick recovery and low morbidity. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Oro-maxilofacial metastases rear presentation of thyroid follicular carcinoma(“Ss. Cyril and Methodius” University, Faculty of Medicine, Skopje, R.N. Macedonia, Department of Anaesthesia and Reanimation, 2017-05); ; ;Maneska M ;Dzikovski I - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Solitary metastatic deposit in the mandible from follicular thyroid carcinoma(Georg Thieme Verlag KG, 2020-07); ; ; ; Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid, after papillary carcinoma. Oral metastasis arising from FTC is very rare. Mandible is more commonly affected than maxilla, with the premolar—molar region being the most frequent site of metastasis. We present the case of a 68yearold female, with swelling in the region of the parotid gland, complaining of periodic rightsided pain in the temporomandibular joint, which occurred most often in the morning with numbness and pain, and difficulty in opening the mouth. After ultrasound and X-ray, the patient was operated and the pathohistological finding was in favor of metastasis of FTC. After 3 months, a total thyroidectomy was performed, and FTC was detected in the right thyroid lobe. Laboratory results were as follows: FT4 = 9.92 pmol/L, thyroid-stimulating hormone = 9.9 mIU/L, and hTG >300 μg/L. Bone scan showed no bone metastasis. Radioablation with 131I of 150 mCi was given to the patient, followed by substitutional therapy with levothyroxine. Mandible metastasis as a single skeletal deposit from follicular thyroid carcinomas is a rare clinical finding. Maxillofacial surgeons should consider and rule out thyroid pathology before performing operation of tumor formation in the mandible region. If feasible, surgical-based treatment options offer the best survival outcomes. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Video-assisted thoracic surgery (VATS) hybrid esophagectomy after neoadjuvant treatment – case report(2023-03-01); ;Igor Dzikovski ;Despot Despotovski ;Faik MisimiMarija SimonovskaEsophageal cancer is an aggressive malignancy. It is 6 th among the leading causes of cancer death and the 8 th most common cancer type worldwide. Regarding gender distribution, esophageal cancer is about 2–4 times more frequent among males than females. There are two main histological types; esophageal squamous cell carcinoma is typically localized in the upper- middle esophagus being the most frequent histological type and adenocarcinoma subtype, usually localized in the lower esophagus. Over the past two decades, video-assisted thoracic surgery (VATS) has revolutionized how thoracic surgeons diagnose and treat esophageal diseases. Because of the advancement of surgical laparoscopic and thoracoscopic procedures and endoscopic instrumentation, minimally invasive esophagectomy (MIE) is performed to enhance surgical outcomes and reduce surgical morbidity. Here, we present a case of, video-assisted thoracic surgery hybrid esophagectomy in a 63-year-old patient with esophageal cancer who had received neoadjuvant therapy. Surgical technique: the patient was first placed in the supine position under general anesthesia and double-lumen intubation. An upper median laparotomy was performed to mobilize and tubulate the stomach conduit. Then we continued with a left lateral decubitus position; 4 cm incision was made in the 5th intercostal space to accommodate the thoracoscopic instruments. The dissection and mobilization of the esophagus were carried out from the esophageal hiatus to the upper thoracic inlet after opening the posterior mediastinal pleura. After this step, the stomach conduit was pulled-up through the esophageal hiatus and laterolateral esophagogastric anastomosis was done in the chest. The postoperative course ended without complications, and the patient was discharged home on the 5th postoperative day. The, video-assisted thoracic surgery hybrid approach is an excellent option for esophageal cancer management, offering a quick recovery and low morbidity.
