Dimitrievska, Deska

Preferred name

Dimitrievska, Deska

Official Name

Dimitrievska, Deska

Main Affiliation

deska.dimitrievska@medf.ukim.edu.mk

Now showing 1 - 10 of 47

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BIOLOGICAL MARKERS OF INFLAMMATION IN PERIPHERAL BLOOD DURING TREATMENT WITH INHALED CORTICOSTEROIDS IN PATIENTS WITH BRONCHIAL ASTHMA
(Elsevier BV, 2007-10)
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Gjorcev, Angelko S.
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Todevski, Dejan L.
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Inflammatory markers in peripheral blood in patients with asthma
(2020-12)
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Dejan Todevski
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Monika Tushevska Mitkovska
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Nikola Chamurovski
Asthma is one of the most common chronic diseases all over the world, resulting from a state of persistent sub-acute inflammation of the airways. The main attribute of asthma is inflammation, which leads to airway remodeling, bronchial hyper-reactivity and reversible or partly reversible airway obstruction. Asthma is a chronic inflammatory disorder of the airways in which many cells and inflammatory mediators play a role. (GINA). Many cells and mediators take part in creating the asthmatic inflammatory reaction, but eosinophils play a central role. All of the inflammatory cells and mediators can be detected in the airflow tissue. Some of them can be detected in the asthmatics peripheral blood too. This study includes 30 patients of the Pulmology and Allergy Clinic, Skopje, with confirmed bronchial asthma, treated with ICS. In all of the patients we followed Eo count, ECP and IL-5 in peripheral blood at the beginning of the study, after 2 and 6 months treatment. Following the parameters during treatment with ICS we registered changes in all of the tested parameters. Our conclusion is that the ICS objectively suppress the inflammatory reaction in asthma and the biologic markers (IL-5, Eo and ECP), which we have followed, can measure the accomplished effect. They could be used in every day practice, not only as diagnostic parameters but also as valid therapeutic guides in the treatment of asthma
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Tobacco dependence
(Macedonian Respiratory Society, 2025-04-13)
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Todevski, Dejan
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Tushevska Mitkovska, Monika
Tobacco is the leading cause of premature death and disability in Europe. Each year, more than 700,000 Europeans die from tobacco-related illness. In Macedonia, 46.6% of the male and 26.8% of the female population are active smokers. These numbers ascertain Macedonia to the high place in Europe by smoking rates. There is nothing more important we can do for patients who smoke than help them stop! Doctors and health professionals must take into account that tobacco dependence is a medical condition and not a habit, vice, pleasure, or life-style choice and it must be diagnosed and treated in the same way as other chronic diseases. Most smokers are not able to stop on their own (without help). Nicotine dependence is a chronic relapsing condition and has two components: physical dependence and psychological dependence. The tenacity of nicotine addiction means that many smokers who attempt to quit will relapse. Relapse is most common within the first few weeks of quitting. The ENSP Tobacco Treatment Guidelines recommend five strategies for addressing tobacco use in clinical settings. Known as the “5As” these strategies are: Ask all patients about smoking status and document in medical record; Advise patients who smoke to quit; Assess readiness to quit; Assist with making a quit attempt, including providing behavioral counselling and prescribing first-line smoking cessation medications; and Arrange follow-up. Behavioral support (Motivational interviewing) is the keystone of tobacco dependence treatment. It is generally matched to the patient’s motivation to quit smoking also known as the patients “stage of change”. There are five stages of change. Pre-contemplation, Contemplation. Preparation, Action and Maintenance. Tobacco dependence may need persistent and repeated therapeutic interventions, as well as long- term follow-up until it is cured. In order to give our contribution to the reduction of tobacco consumption in Macedonia, we are implementing a program for education of doctors and health workers for smoking cessation. The project represents partnership between the Medical faculty in Skopje and the Henry Ford Health System from Detroit, Michigan, USA.
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Active Smoking is Associated with Lower Dialysis Adequacy in Prevalent Dialysis Patients
(Scientific Foundation Spiroski (publications), 2019-11-15)
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Mladenovska, Daniela
Dialysis adequacy measured by single pool Kt/V (spKt/V) lower than 1.2 or urea reduction rate (URR) lower than 65% is associated with a significant increase in patient mortality rate. Patients' adherence to the medical treatment is crucial to achieve recommended targets for spKt/V. Smoking is a recognized factor of non-adherence.
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Continuous effect of migrant crisis on smoking status among migrants
(European Respiratory Society, 2020)
Monika Tushevska Mitkovska
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Nikola Chamurovski
Introduction: Acknowledging the specific problems of smoking prevalence and cessation in specific high risk populations in 2018, we have conducted a pilot research among migrants in the transitional refugee camps in Bosnia and Hercegovina, to evaluate their smoking habits, showing that migrants crisis has a negative impact on their smoking status. Objective and Method: We aimed to compare and follow the continuous effect of the crisis on the smoking habits, in order to provide data for developing a strategy that can be implemented as an continuous measure in the smoking cessation. From November untill December 2019 we interviewed a total of 368 randomly selected, migrants accommodated in the transitional camps, average length of stay of 70 days. We interwieved 333 men (90%), and 35 women (10%), age of 14-57 with the same questionnaire from the pilot study. Results: 60% were active smokers and 40% were nonsmokers.110 migrants(50%) responded that they have increased the amount of smoked cigarettes since they left they homeland, 65(20%) are smoking less cigarettes compared to the period before they left their homeland, 8(4%) have no difference in the number of smoked cigarettes, 36(16%) have started smoking since they left their homeland. None of the migrants had answered that they quit smoking since they left their homeland. Conclusion: Our data confirmed that the migration crisis has negative impact on the smoking habits of migrants. There was increase of the smoking prevalence and worsening of the smoking status true the migration crisis. We emphasize the need for organizing education and support in the process of quitting smoking for this vulnerable group.
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LEUKOTRIENE RECEPTOR ANTAGONISTS IN MANAGING SEVERE UNCONTROLLED ASTHMA
(European Medical Group, 2017-08-03)
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Goseva, Zlatica
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Gjorchev, Angelko
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IL-33 in patients with severe uncontrolled allergic asthma
(European Respiratory Society, 2017-09)
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Goseva, Zlatica
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Angelko, Gjorcev
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Rule - Based Model for Medical Knowledge Presentation and Reasoning in Clinical Decision Support Systems
(Springer International Publishing, 2016)
Aleksovska-Stojkovska, Liljana
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Educational courses improve asthma management and treatment
(Elsevier BV, 2007-11)
Gjorcev, Angelko
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Goseva, Zlatica
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Todevski, Dejan
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A longitudinal outcomes evaluation of an adapted Certified Tobacco Treatment Specialist (aCTTS) for physicians in the Former Yugoslavian Republic of Macedonia (FYROM)
(European Publishing, 2018-06-13)
Kaljee, Linda
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Plum, Alexander
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Trajkova Lazarevska, Magdalena

Dimitrievska, Deska

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