Stefanovska, Jovana

Preferred name

Stefanovska, Jovana

Official Name

Stefanovska, Jovana

Main Affiliation

jstefanovska@fvm.ukim.edu.mk

Now showing 1 - 10 of 47

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Seroprevalence of Toxoplasma gondii infection in farmed saws in Republic of Macedonia
(Faculty of Veterinary medicine in Skopje, 2016-09)
Angjelovski Branko
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Radeski Miroslav
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Field surveys in Croatia and North Macedonia reveal two novel phleboviruses circulating in sandflies
(Microbiology Society, 2021-11)
Ayhan, Nazli
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Alten, Bulent
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Ivovic, Vladimir
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Sandfly-borne phleboviruses are distributed widely throughout the Mediterranean Basin, presenting a threat to public health in areas where they circulate. However, the true diversity and distribution of pathogenic and apathogenic sandfly-borne phleboviruses remains a key issue to be studied. In the Balkans, most published data rely on serology-based studies although virus isolation has occasionally been reported. Here, we report the discovery of two novel sandfly-borne phleboviruses, provisionally named Zaba virus (ZABAV) and Bregalaka virus (BREV), which were isolated in Croatia and North Macedonia, respectively. This constitutes the first isolation of phleboviruses in both countries. Genetic analysis based on complete coding sequences indicated that ZABAV and BREV are distinct from each other and belong to the genus Phlebovirus, family Phenuiviridae. Phylogenetic and amino acid modelling of viral polymerase shows that ZABAV and BREV are new members of the Salehabad phlebovirus species and the Adana phlebovirus species, respectively. Moreover, sequence-based vector identification suggests that ZABAV is mainly transmitted by Phlebotomus neglectus and BREV is mainly transmitted by Phlebotomus perfiliewi. BREV neutralizing antibodies were detected in 3.3% of human sera with rates up to 16.7% in certain districts, demonstrating that BREV frequently infects humans in North Macedonia. In vitro viral growth kinetics experiments demonstrated viral replication of both viruses in mammalian and mosquito cells. In vivo experimental studies in mice suggest that ZABAV and BREV exhibit characteristics making them possible human pathogens.
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Regional Risk Assessment for West Nile in Former Yugoslav Republic of Macedonia (FYROM)
(Società Italiana di Diagnostica di Laboratorio Veterinaria (SIDiLV), 2018-11-09)
Gavaudan, S.
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Angeloni, G.
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Barchiesi, F.
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Pasquali, P
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In the last decade several outbreaks of West Nile (WN) Disease were reported in humans and animals in Balkans, including FYROM. During 2017 a Risk Assessment (RA) for WN, was made in FYROM by IZS Umbria e Marche, in collaboration with the local Health Authorities. On the basis of historical data, from 2011 to 2017, 22 human cases of WN were notified. In animals, during 2011-12, 1293 domestic birds and 316 horses were tested for WN, highlighting a prevalence respectively of 5.6% and 3,2%. The mosquitoes population was investigated with traps confirming the presence of Culex pipiens, the main vector of WN. The presence of Aedes albopictus was also documented for the first time in FYROM. Every step of the RA has been accompanied from a field and laboratory training. Finally, a WN Surveillance Plan involving birds, equids and mosquitoes was proposed at FYROM health authorities, as recommended for WN by ECDC when, on the basis of a Risk Assessment, an endemic condition is recognized.
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Prevalence of cystic echinococcosis among cattle and sheep in the Republic of Macedonia
(ISS, Rome, Italy, 2018-05)
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Rashikj, Ljubica
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Meshterovikj, Srgjan
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Radeski, Miroslav
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Direct evidence for an expanded circulation area of the recently identified Balkan virus (Sandfly fever Naples virus species) in several countries of the Balkan archipelago
(Springer Science and Business Media LLC, 2017-08-29)
Ayhan, Nazli
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Alten, Bulent
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Ivovic, Vladimir
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Dvořák, Vit
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Martinkovic, Franjo
Recently, Balkan virus (BALKV, family Phenuiviridae, genus Phlebovirus) was discovered in sand flies collected in Albania and genetically characterised as a member of the Sandfly fever Naples species complex. To gain knowledge concerning the geographical area where exposure to BALKV exists, entomological surveys were conducted in 2014 and 2015, in Croatia, Bosnia and Herzegovina (BH), Kosovo, Republic of Macedonia and Serbia.
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First comprehensive study on West Nile in the former Yugoslav Republic of Macedonia (FYROM)
(EFSA, Parma, Italy, 2018-09)
Meshterovikj, Srgjan
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Pasquali, Paolo
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SHORT OVERVIEW OF PARASITIC ZOONOTIC DISEASES IN R.MACEDONIA AND ONE HEALTH APPROACH
(Macedonian Medical Society, Association of Microbiologists of Macedonia, 2018-06)
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Rashikj, Ljubica
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Jurhar Pavlova, Maja
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Seroprevalence of canine leishmaniosis in asymptomatic dogs in Kosovo
(Springer Science and Business Media LLC, 2022-12-20)
Xhekaj, Betim
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Sherifi, Kurtesh
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Rexhepi, Agim
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Bizhga, Bejo
Canine leishmaniosis (CanL) is a neglected zoonotic disease caused by Leishmania spp. Leishmania infantum is the species responsible for the zoonotic form of the disease where dogs are reservoir hosts. This study aimed to determine the seroprevalence of CanL in asymptomatic dogs in Kosovo. Blood samples were collected from 285 dogs in all seven regions in Kosovo (35-50 samples per region) from summer 2021 to spring 2022. Sera were tested using enzyme-linked immunosorbent assay (ELISA), and the presence of anti-Leishmania IgG was confirmed by an indirect fluorescent antibody test (IFAT). The true overall seroprevalence of CanL of asymptomatic dogs in Kosovo with ELISA was 4.21% (95% CI: 2.42-7.21) while with IFAT was 3.51% (95% CI: 1.92-6.34). The highest rates were found in the Prishtina region to be 8.0% (4/50) by ELISA and 6.0% (3/50) by IFAT, and in the Mitrovica region, the prevalence was 0% (0/40). There were no significant differences among the different regions, gender, age, health status, and breed. These findings highlight the presence of CanL in most regions of Kosovo and underline the veterinary relevance of clinically asymptomatic dogs infected with Leishmania.
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Red mark syndrome in rainbow trout farmed in the Republic of Macedonia: First observation
(Faculty of Veterinary medicine in Skopje, 2016-09)
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Angjelovski Branko
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Dijana Blazhekovikj - Dimovska
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Vasil Kostov
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Rodne Nastova
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The tree that hides the forest: cryptic diversity and phylogenetic relationships in the Palaearctic vector Obsoletus/Scoticus Complex (Diptera: Ceratopogonidae) at the European level
(Springer Science and Business Media LLC, 2020-05-20)
Mignotte, Antoine
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Garros, Claire
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Gardès, Laetitia
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Balenghien, Thomas
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Duhayon, Maxime
Culicoides obsoletus is an abundant and widely distributed Holarctic biting midge species, involved in the transmission of bluetongue virus (BTV) and Schmallenberg virus (SBV) to wild and domestic ruminants. Females of this vector species are often reported jointly with two morphologically very close species, C. scoticus and C. montanus, forming the Obsoletus/Scoticus Complex. Recently, cryptic diversity within C. obsoletus was reported in geographically distant sites. Clear delineation of species and characterization of genetic variability is mandatory to revise their taxonomic status and assess the vector role of each taxonomic entity. Our objectives were to characterize and map the cryptic diversity within the Obsoletus/Scoticus Complex.

Stefanovska, Jovana

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