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    Computed tomography or magnetic resonance imaging - our experiences in determining preoperative TNM staging of bladder cancer
    (Macedonian Academy of Sciences and Arts, 2013)
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    Lazarova, Aleksandra
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    Posterior cerebral artery – variation in the origin and clinical significance
    (Macedonian Academy of Sciences and Arts, 2014-04-01)
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    Aliji, Vjolca
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    With the introduction of new techniques in diagnostic and interventional radiology and progress in micro-neurosurgery, accurate knowledge of the brain blood vessels is essential in daily clinical work. The aim of this study was to describe the different types of PCA origin, their diameter, and to emphasize their clinical significance. In this study we examined radiographs of 53 patients who had CT angiography undertaken for a variety of clinical reasons, performed as a part of their medical treatment at the University Radiology Clinic in Skopje, R. Macedonia. This study included 24 females and 29 males, ranging in age from 32 to 73 years; mean age 55.3 ± 11.5 years. The results showed that the diameter of the posterior cerebral artery was 1.74 ± 0.317 mm on the right side and 1.98 ± 0.408 mm on the left side. The adult configuration was present in 37 (69.81%); foetal configuration was present in 12 (22.64%) and transitional configuration was present in 4 (7.54%) of the patients. We found two patients with bilateral foetal type and ten with unilateral foetal type (six on the right side and four on the left side). Despite the limitations of the study, we found that the foetal variant was presented in 22.64% of patients. Thorough knowledge of the anatomy of the intracranial vessels is important to clinicians as well as basic scientists who deal with problems related to intracranial vasculature on a daily basis.
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    Neuro-Behcet syndrome: presentation of a case
    (2014-10)
    Vjolca Aliji
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    Dejan Daskalov
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    Role of DWI/ADC in evaluation of brain tumor and monitoring treatment response
    (2016-09-22)
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    Vjolca, Aliji
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    Daskalov, Dejan
    DWI consists of a DW image-diffusion trace and ADC map. DW image is a T2-weighted echo planar background image attenuated by the rate of apparent diffusion and with qualitative and quantitative assessment of the ADC map provide distinction of cytotoxic and vasogenic edema. DWI/ADC is used to assess brain tumors, tumor grading by providing information about tumor cellularity- prediction of tu grade. In high grade tumors DWI/ADC evaluate diffuse unenchancing spread and terapeutic response. ADC value of high grade gliomas has been shown to be lower than that of low-grade gliomas. In extra axial meningioma low ADC in atypical vs typical subtypes. Primary neoplasms- peritumoral edema/infiltration = low ADC vs secondary lesions. Lymphoma - high DWI/ low ADC due to its cellularity. DWI/ADC of therapeutic response provide information about post oper margin of surgical resection (ischemia, pyogenic infection-reduction of ADC). Useful in following treatment response and recurrence because cytotoxic chemoradiation reduce cellularity - increase ADC. Radiation necrosis usually showed heterogeneity on DWI images and often included spotty, marked hypointensity (Chiaki Asaoa, et al.AJNR2005). DWI useful in differentiating recurrent neoplasm from radiation necrosis. Material and method: We evaluate 33 cases with brain tumor. 19 of them after operative and/or chemoradiation therapy. All of them underwent on brain MRI enhanced with DWI/ADC, B-value o and 1000s/mm2 on 1,5T SIMENS Avanto. Results: From intraaxial tumor: 4 cases of glioma gr1; 5 gr2; 3 gr3 and 9 gr4; extraaxial 7 from witch 2 atypical and 5 secondary lesions. Follow up on operated gr2 and follow up on oper. and chemoradiated gr3 and 4 with detection of postradiation necrosis, residual tumor and recidiv however transformation in higher grade. Conclusion: Information about tumor type, malignancy grade, and the presence of necrosis is useful to determine the most suitable and effective treatment procedures. Serially obtained diffusion data is useful to document and even predict cellular response to drug or radiation therapy. Today DWI/ADC is necessary tool in CNS examination. DWI practical, useful, requires less imaging time vs other advance techniques but alone insufficient.
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    Differential Diagnosis of Diffuse Cystic Lung Disease at HRCT - An Overview
    (Biomedical & Clinical Research (Biores Scientia), 2024)
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    Introduction: The diffuse cystic lung diseases (DCLDs) are a diverse group of lung disorders characterized by the presence of multiple regular or irregular spherical parenchymal lucencies bordered by a thin wall and having a well-defined interface with normal lung. Other lucent lung lesions like centrilobular emphysema, cavity, cystic bronchiectasis, honeycomb cyst, and pneumatoceles are close mimics of a lung cyst on high-resolution computed tomography (HRCT) HRCT is an important modality in the evaluation of interstitial lung disease to include cystic lung disease. This review describes a simple algorithmic approach for DCLDs on HRCT based on cyst’s distribution, size, and shape, as well as background parenchymal changes and it helps also in differentiation of common and uncommon diffuse cystic lung disease. Aim: The aim of the study is to present, describe and make differential diagnosis of this spectrum of diseases associated with air cysts at high-resolution CT. Conclusion: Diffuse cystic lung diseases are a group of complex disorders that often have an overlapping clinical presentation, but different underlying pathological processes. HRCT still remains the imaging of choice for the diagnosis of common diffuse cystic lung diseases.
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    Pulmonary manifestation of sarcoidosis detected on high resolution computed tomography
    (Macedonian Association of Anatomists, 2023)
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    Sarcoidosis is a multisystemic disease of unknown etiology that mostly affects the lung parenchyma with interstitial and granulomatous changes of varying intensity and expression depending on the stage of the disease. In addition to the parenchyma and interstitium, the mediastinal lymph nodes are also very often affected. To analyze the distribution and characteristics of interstitial lung lesions and the involvement of mediastinal lymph nodes in pulmonary sarcoidosis by the method of high-resolution computed tomography.15patients diagnosed with pulmonary sarcoidosis were included in the study. Computed tomography with high resolution was made on 128 slice CT scanner PHILIPS INCISIVE, using 1 mm thin-slice thickness and high spatial frequencies algorithm for image reconstruction. Lymph nodes are classified as hilar and mediastinal with a maximum diameter of short axis of more than 10 mm taken as their enlargement. Pulmonary changes are classified as nodules, reticular opacities, fibrous lesions, ground glass opacities and consolidations. The predominant distribution of lesions in the upper and middle zones of the lungs compared to the lower zones was noted. The disease is graded in 5 stages with the Scadding classification. 15cases of patients diagnosed with sarcoidosis were analyzed all of whom are women in the age group of 30-60 years old. Two patients are in stage I and three are in III stage of the disease, 6patients are in stage II of sarcoidosis and 4 are in stage IV of the disease. Dry cough as a symptom predominates in all patients, while dyspnea is graded according to the mMRC scale. Mediastinal lymphadenopathy with and without calcifications was present in 11patients. The type of lung changes as well as their distribution are presented in graphs. HRCT is the method of choice in the evaluation of pathological changes in pulmonary sarcoidosis. It very precisely shows us the characteristic appearance of nodules and lesions, their distribution and atypical changes and helps us in grading the disease and its treatment.
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    Clinical significance of the vertebral artery hypoplasia
    (Macedonian Association of Anatomists and Morphologists, 2013)
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    Because of their anatomical localization, vertebral arteries were neglected in research for a long period of time. Vertebral arteries are responsible for about 30% of the brain blood supply. The aim of this study was to analyze the normal and variable dimensions of the vertebral artery size such as hypoplasia and aplasia, and to emphasize the clinical importance of these congenital variations. For the purpose of this study we examined radiographs of 30 patients who had CT angiography undertaken for a variety of clinical reasons, performed as a part of their medical treatment at the University Clinic for Radiology in Skopje, R. Macedonia. We analyzed CT reports for the diameter of the vertebral artery. The diameter of the left vertebral artery was from 1.6-5.20 mm, average 3.35 mm. The diameter of the right vertebral artery was from 1.64-5.40 mm, average 3.19 mm. Hypoplasia of the vessel was found in four patients. We found no aplasia of the vessel in this series. Vertebral artery hypoplasia is common in the Macedonian population and can be reliably diagnosed on CT scans. Our study has highlighted the clinical significance of vertebral artery hypoplasia in stroke and migraine.
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    ДЕГЕНЕРАТИВНО ЗАБОЛУВАЊЕ НА ЦЕРВИКАЛНИОТ СЕГМЕНТ ОД ‘РБЕТОТ КАЈ ПАЦИЕНТИ СО ЦЕРВИКОБРАХИЈАЛЕН СИНДРОМ
    (SHMSHM - AAMD, 2020)
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    Janevski, Georgi
    Вовед: Една од главните причини за рефракторна вратна болка е дегенеративното заболување на цервикалниот сегмент од `рбетот. Наша цел е да го прикажеме типот на дегенеративното заболување на цервикалниот сегмент од `рбетот кај овие пациенти. Материјали и методи: Студијата е аналитичка-трансверзална студија во која беа користени МР прегледите на цервикалниот `рбет и податоците од прашалниот дизајниран за оваа студија. Фокусната група се состои од 98 испитаници на возраст од 35-70 год. со рефракторна вратна болка. Резултати: Нашата студија покажа дека кај 77 испитаници постои надув на еден или повеќе интервертебрални дискови додека кај 50 испитаници резултатите од МР на цервикалниот сегмент од ‘рбетот покажаа дека постои протрузија на еден или повеќе интервертебрални дискови. Ваквиот наод незначајно е асоциран и со трауматска повреда на вратот (Chi-square=0,54 df=1 p=0,46). Заклучок: Надув на интервертебрален диск на цервикалниот сегмент од ‘рбетот како патолошка промена е чест кај симптоматските пациенти и се регистрира кај 78,57% од испитаниците. Од друга страна појавата на дискус хернија не е толку честа и се јавува кај нешто повеќе од половина од испитаниците (51,02%).
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    Multidetector CT Angiography retrospective study of fetal origin of posterior cerebral artery of the population in R. Macedonia
    (2013-10-03)
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    Janevski, Georgi
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    Aliji, Vjolca
    BACKGROUND AND PURPOSE: Fetal origin of the posterior cerebral artery is a common anatomic variation in the posterior cerebral circulation. It is estimated to occur in up to 30% individuals. The aim of this study is to show the incidence of unilateral and bilateral fetal origin of he posterior cerebral artery of the population in R. Macedonia. MATERIALS AND METHODS: The sensitivity and specificity of multidetector CT angiography are reported to be high (819-90% and 93%, respectively). Retrospectively we reviewed random multidctector CT Angiography studies of 100 patients in our clinic, to determine the incidence of fetal origin of the PCA of the population in R. Macedonia ( sex and age was not taken into account) RESULTS: Form the randomly selected 100 individuals examined in our clinic in the last year, 32 (32%) had fetal PCA, and only 4(49) of those had bilateral fetal PCA. From the 28 individuals with unilateral fetal origin of the posterior cerebral artery, 19 had right fetal PCA and 9 had left fetal PCA. CONCLUSION: The study showed that the incidence of fetal origin of posterior cerebral artery of the examined population in R. Macedonia Is 32%. The incidence of unilateral fetal PCA Is 29% and of bilateral fetal PCA IS 4%. From all the examinees 19% have unllateral right and 9% unilateral left fetal PCA.