Mironska, Kristina

Preferred name

Mironska, Kristina

Official Name

Mironska, Kristina

Alternative Name

Mironska Kristina

Kristina Mironska

Mironska K

K Mironska

Kristina, Mironska

Миронска Кристина

Кристина Миронска

Миронска К

К. Миронска

Миронска К.

К Миронска

Mironska S Kristina

Kristina S Mironska

Mironska K.

Main Affiliation

kristina.mironska@medf.ukim.edu.mk

Now showing 1 - 10 of 17

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Adverse Reactions to Intravenous Immunoglobulins - Our Experience
(ID-Design/Scientific foundation SPIROSKI, 2018-12-20)
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Arjeta Hasani
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Values of lymphocyte subpopulations in healthy Macedonian children under the age of five
(International Medical Association Bulgaria (IMAB) / Peytchinski Publishing Ltd., 2016-12)
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Background: The effects of demographic factors on a wide range of immunological variables demonstrate the importance of having normative data representative of particular patient population. There was no lymphocyte subpopulation data for Macedonian children and the purpose of this study was to establish such a data. Subject and methods: The study population consists of 87 healthy children. Subjects were grouped into four age categories as follows: group 1 age range 5d-10d (n=15); group 2 age range 1 mo-1 yr (n=18); group 3 age 1yr-2 yr(n=20) and group 4 age 2yr-5 yr(n=34 Monoclonal antibodies labeled with fluorochromes and immunofluorescent microscopy were used to detect cells bearing specific cell markers. Results: The mean lymphocyte cell count gradually fell with increasing age from 6,65x10^9/l in group 1, to 5,67x10^9/l in group 2, 4,55x10^9/l in group 3, and to 4,14x10^9/l in group 4. Absolute values of CD3, CD4 and CD20 positive cells decreased gradually with age. Significant differences in mean absolute values were observed for absolute lymphocyte counts between groups 1/2 and 1/4 (P<0,01) and groups 2/4(P<0,05); for CD3 positive lymphocytes between groups 1/3(P<0,05) and 1/4(P<0,01); for CD4 positive lymphocytes between groups 1/3 (P<0,05) and 1/4(P<0,01) and for CD20 positive lymphocytes between groups 1/3 and 3/4(P<0,05) and groups 1/4 (P<0,01). Significant difference for CD4/CD8 ratio and for percentage values of different lymphocyte subpopulations between the different age groups was not found. Conclusion: This data may serve as a reference range for studies of Macedonian pediatric subjects.
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IGF1R Gene Alterations in Small for Gestational Age (SGA) Children
(ID-Design/Scientific foundation SPIROSKI, 2018-05-20)
Aleksandra Janchevska
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Aleksandar Dimovski
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IGF1R Gene Alterations in Children Born Small for Gestitional Age (SGA)
(ID-Design/Scientific foundation SPIROSKI, 2018-11-25)
Aleksandra Janchevska
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Marina Krstevska-Konstantinova
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Heike Pfäffle
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Marina Schlicke
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Nevenka Laban
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Sindroma inflamatore multisistemike te femijet e asocuar me SARS-Covid 2 – karakteristikat klinike dhe trajtimi.
(Medicus 2021, Vol. 26 (3): 330-338., 2021-12)
A. Hasani
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Hyrje: Sindroma multisistemike inflamatore tek femijet (MIS-c) eshte gjendje e rralle por serioze e cila lidhet me infekcionin SARS-COVID-2. Qellimi i ketij punimi eshte publikimi i pervojes tone me femije me MIS. Pershkrimi i simptomeve klinike, analizave laboratorike, mikrobiologjike dhe trajtimit do te sherbej ne rritjen e njohurive per kete syndrome te re tek femijet. Rezultatet: Jane pershkruar simptomet, shenjat klinike, analizat laboratorike dhe mikrobiologjike ne 18 femije te hospitalizuar ne repartin e Imunologjise ne periudhen dhjetor 2020-shtaror 2021. Te gjithe femijet jane pranuar ne repart me vlera te larte te parametrave inflamator, me temperature te larte minimum 3 dite para pranimit si dhe analiza serologjike pozitive per SARS-COVID2 infekcion. Ne asnje femije nuk eshte izoluar patogjen mikrobiologjik si shkaktar i mundshem etiologjik. Simptomet me te shpeshta ishin ato te traktit gastrointestinal ne 88.8% te femijeve. Ndryshimet ne lekure, edeme dhe hipotensioni ishin te pranishem ne 61.1% te rasteve. 4 femije (22.2%) ishin me simptome e shenja te apendicitit akut, tre prej te cileve jane operuar, nje eshte trajtuar ne menyre konzervative. 3 femije ishin me miokardit/perikardit dhe me pankreatit akut. Vetem nje femije (5.5%) ishte me shenja te insuficiences akute renale. Perfundimi: Femijet me MIS mund te kerkojne trajtim intenziv pediatric dhe qasje multidiciplinare ne trajtim.Njohja dhe identifikimi I hershem I kesaj gjendje si dhe udhezimi ne kohe per trajtim specialistik eshte me rendesi te veqante.
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Metabolic Profiles in Obese Children and Adolescents with Insulin Resistance
(ID-Design/Scientific foundation SPIROSKI, 2018-03-15)
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Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: a cohort study
(Elsevier BV, 2009-06)
Tóth, Beáta
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Volokha, Alla
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Mihas, Alexander
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Pac, Malgorzata
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Bernatowska, Ewa
Primary immunodeficiency disorders are a recognized public health problem worldwide. The prototype of these conditions is X-linked agammaglobulinemia (XLA) or Bruton's disease. XLA is caused by mutations in Bruton's tyrosine kinase gene (BTK), preventing B cell development and resulting in the almost total absence of serum immunoglobulins. The genetic profile and prevalence of XLA have not previously been studied in Eastern and Central European (ECE) countries. We studied the genetic and demographic features of XLA in Belarus, Croatia Hungary, Poland, Republic of Macedonia, Romania, Russia, Serbia, Slovenia, and Ukraine. We collected clinical, immunological, and genetic information for 122 patients from 109 families. The BTK gene was sequenced from the genomic DNA of patients with a high susceptibility to infection, almost no CD19(+) peripheral blood B cells, and low or undetectable levels of serum immunoglobulins M, G, and A, compatible with a clinical and immunological diagnosis of XLA. BTK sequence analysis revealed 98 different mutations, 46 of which are reported for the first time here. The mutations included single nucleotide changes in the coding exons (35 missense and 17 nonsense), 23 splicing defects, 13 small deletions, 7 large deletions, and 3 insertions. The mutations were scattered throughout the BTK gene and most frequently concerned the SH1 domain; no missense mutation was detected in the SH3 domain. The prevalence of XLA in ECE countries (total population 145,530,870) was found to be 1 per 1,399,000 individuals. This report provides the first comprehensive overview of the molecular genetic and demographic features of XLA in Eastern and Central Europe.
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Kwashiorkor from dietary restriction secondary to cow's milk allergy
(SHMSHM/AAMD, 2020)
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Hasani A
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Bojadzieva S
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A novel mutation in SLC39A7 identified in a patient with autosomal recessive agammaglobulinemia: The impact of the J Project
(Wiley, 2022-06)
Erdős, Melinda
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Hasani, Arijeta
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Fifteen years of the J Project
(Springer, 2019-05-17)
Lazslo Maródi
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Abolhassani, Hassan
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Aghamohamaddi, Asghar
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Avcin, Tadej
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Bataneant, Michaela

Mironska, Kristina

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