Bogdanovska Todorovska, Magdalena
Preferred name
Bogdanovska Todorovska, Magdalena
Official Name
Bogdanovska Todorovska, Magdalena
Main Affiliation
Email
magde_b981@yahoo.com
magdalena.todorovska@medf.ukim.edu.mk
40 results
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Item type:Publication, Decoupling channel count from field of view and spatial resolution in single-sensor imaging systems for fluorescence image-guided surgery(SPIE-Intl Soc Optical Eng, 2022-09-26) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of Size of the Tumour, Persistence of Estrogen Receptors, Progesterone Receptors, HER2Neu Receptors and Ki67 Values on Positivity of Axillary Lymph Nodes in Patients with Early Breast Cancer with Clinically Negative Axillary Examination(2017-12-15); ; ; ; The study aimed to identify factors that influence the positivity of axillary lymph nodes in patients with early breast cancer and clinically negative axillary lymph nodes, who were subjected for modified radical mastectomy and axillary lymphadenectomy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Recommmendations for the diagnostic algorithm in lung cancer. Consensus statement of the Macedonian respiratory society and the Macedonian association of pathology(Македонско лекарско друштво = Macedonian Medical Association, 2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Interventional procedure in breast lesions- core-biopsy(Macedonian Association of Anatomists and Morphologists, 2017); ; ; ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Standardization and optimization of fluorescence in situ hybridization (FISH) for HER-2 assessment in breast cancer: A single center experience(Association of Basic Medical Sciences of FBIH, 2018-05-20); ; ; ; <jats:p>Accurate assessment of human epidermal growth factor receptor 2 (HER-2) is crucial in selecting patients for targeted therapy. Commonly used methods for HER-2 testing are immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Here we presented the implementation, optimization and standardization of two FISH protocols using breast cancer samples and assessed the impact of pre-analytical and analytical factors on HER-2 testing. Formalin fixed paraffin embedded (FFPE) tissue samples from 70 breast cancer patients were tested for HER-2 using PathVysion™ HER-2 DNA Probe Kit and two different paraffin pretreatment kits, Vysis/Abbott Paraffin Pretreatment Reagent Kit (40 samples) and DAKO Histology FISH Accessory Kit (30 samples). The concordance between FISH and IHC results was determined. Pre-analytical and analytical factors (i.e., fixation, baking, digestion, and post-hybridization washing) affected the efficiency and quality of hybridization. The overall hybridization success in our study was 98.6% (69/70); the failure rate was 1.4%. The DAKO pretreatment kit was more time-efficient and resulted in more uniform signals that were easier to interpret, compared to the Vysis/Abbott kit. The overall concordance between IHC and FISH was 84.06%, kappa coefficient 0.5976 (p < 0.0001). The greatest discordance (82%) between IHC and FISH was observed in IHC 2+ group. A standardized FISH protocol for HER-2 assessment, with high hybridization efficiency, is necessary due to variability in tissue processing and individual tissue characteristics. Differences in the pre-analytical and analytical steps can affect the hybridization quality and efficiency. The use of DAKO pretreatment kit is time-saving and cost-effective.</jats:p> - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Consensus statement: RECOMMENDATIONS FOR THE DIAGNOSTIC ALGORITHM IN LUNG CANCER CONSENSUS STATEMENT OF THE MACEDONIAN RESPIRATORY SOCIETY AND THE MACEDONIAN ASSOCIATION OF PATHOLOGY(Македонско лекарско друштво = Macedonian Medical Association, 2019); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Multispectral imaging sensors for detecting UV endogenous and NIR exogenous fluorophores(SPIE Digital Library, 2024-03-13) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A 3.47 e<sup>−</sup> Read Noise, 81 dB Dynamic Range Backside-Illuminated Multispectral Imager for Near-Infrared Fluorescence Image-Guided Surgery(IEEE, 2020-10) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Identification of Sentinel Lymph Node in Breast Cancer with three Tracers (Radiocolloid, Methylene blue, and Indocyanine Green). (Case Report)(Scientific foundation SPIROSKI, 2020-09-10); ; ; BACKGROUND: Sentinel lymph node (SNL) biopsy in breast cancer for the determination of axillary status is standard procedures in surgical treatment of early-stage breast cancer. The identification of the SNL is usually performed by radiocolloid injection or/and injection of methylene blue due. The use of indocyanine green (ICG) dye, which is fluorescent dye, which movement in breast and axillar pit, can be followed with special cameras which detect near infrared specatar of light. CASE REPORT: In this paper, we present case report of patient with breast cancer, where we perform SNL detection with three methods: Use of radiocolloid which we trace with static gamma camera, and intraoperatively with hand held gamma probe, methylene blue dye which movement we followed by eye contact and using indocyanine green which movement was followed by specially constructed multispectral camera, which can detect near-infrared fluorescence that is emitted by ICG and methyline blue, respectively. CONCLUSION: Fluorescent imaging with ICG is a sensitive, valuable, and safe method for SNL biopsy. Finding new agents that would identify the SNL, especially if they are not radioactive would be an important step in wider application of this method. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, DIAGNOSTIC AND THERAPEUTIC MODALITIES IN THE MANAGEMENT OF A PATIENT WITH OCULAR SURFACE SQUAMOUS NEOPLASIA (OSSN)-CASE REPORT AND REVIEW(University Ss. Cyril and Methodius in Skopje, 2022);