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    Item type:Publication,
    A survey for students’ experience in small group learning classroom of histology
    (Macedonian Association of Anatomists, 2019)
    Liljana Milenkova
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    Small group learning during practical sessions of histology & embryology was adopted to overcome students’ ‘authority-dependence’ and to enable creative thinking and learning in a socially cohesive group, for enhancing the learning process and developing certain skills. The study aims to identify students’ perception of the usefulness (in general) as well as of certain advantages of the learning process and gaining self-confidence. Online survey consisting of 13 questions/statements the students are supposed to give opinion on, by stating degree of agreement. Results are based on a four grade Likert type scale of evaluation. About half of the students practicing small group learning for the first time, expressed a strongly positive opinion in the survey. They find this method of cooperative learning favorable for: enhancement of the learning process, rational organization of time, conclusion drawing, learning how to apply knowledge in practice, rising motivation. Over all, students practicing small group learning for the first time find the cooperative learning very useful. They elucidate its positive effect on time organization and rationalization of the learning process and knowledge applying. The findings are encouraging and motivating for our continuous work with small group learning. They also highlight the need of working on improvement and creating additional ways to promote students’ participation - especially in questioning, answering and statement elaborating. This project has got ethical approval from the Committee for ethical research with humans. The survey which is part of the project was performed with the understanding and consent of the students.
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    Item type:Publication,
    Histophysiology of the spleen after application of medroxyprogesterone acetate
    (1998)
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    The aim of our study was to determine the activity of medroxiprogesterone acetate (MPA) on the histophysiology of the biggest lymphatical organ, the spleen. The experiment was performed using 24 female Wister rats. The first, control group of 12 rats received physiological solution daily, whereas the other group, MPA in a dose of 15.0 mg/kg bw intramuscularly in a period of 30 days. The histological analysis of the spleen showed an obvious reduction of the lymph follicles which were in an involuntary phase with inactive germinal centers. Destructive changes in tissue were registered in the close distance of which a more intensive development of connective tissue was noticed into which collagen fibres predominate. The stereological analysis showed decrease of volume density of the white pulp from 13,42 ± 2,12% (medium value ± standard deviation) to 7,14 ± 1,92% (p < 0,001). The volume density of the marginal zone increased from 36,91 ± 4,44% to 52,38 ±15,14% (p< 0,001) and the volume density of the red pulp dropped from 49,69 ± 5,18% to 38,1 ± 7,15% (p< 0,001).