Georgievska, Jadranka
Preferred name
Georgievska, Jadranka
Official Name
Georgievska, Jadranka
Translated Name
Јадранка Георгиевска
Alternative Name
Georgievska J.
Jadranka Georgievska
J.Georgievska
Јадранка Георгиевска
Георгиевска Ј.
Main Affiliation
Email
jadranka.georgievska@medf.ukim.edu.mk
29 results
Now showing 1 - 10 of 29
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Item type:Publication, SUCCESSFULLY DELAYED DELIVERY OF SECOND TWIN AFTER EARLY SECOND TRIMESTER RUPTURE OF MEMBRANES OF THE FIRST TWIN: A CASE REPORT(Институт за јавно здравје на Р Северна Македонија = Institute of Public Health of R North Macedonia, 2020-07); ; ; Twin pregnancies are high-risk pregnancies accompanied with multiple complications, such as: spontaneous abortion, preterm rupture of the membranes, preterm delivery, intrauterine death of one or both twins etc. There is no consensus about the management of twin pregnancies complicated with preterm rupture of the membranes of one twin and risk of preterm delivery. These cases are rarely found in the literature. We present a case of a 35 years old patient, hospitalized in a tertiary level institution, because of a diamniotic dichorionic twin pregnancy complicated with preterm rupture of the membranes of the first twin at 19 weeks of gestation. She had one delivery with Caesarean section 16 years ago. In consultation with the patient induction of labor was done with delivery of the first twin, a death male fetus. After that, antibiotics and tocolytic therapy were administrated and the patient remained in the hospital about one week. The patient was discharged at home with regular control of her condition and condition of the fetus. The patient was again hospitalized at 33 weeks of gestation with uterine contractions on cardiotocography. After administration of corticosteroid therapy for fetal lung maturation she delivered spontaneously the second twin in a good condition and she was discharged from hospital after 16 days. In twin pregnancies clinicians must think about delayed interval delivery of the second twin, after delivery of the first twin, with an aim to increase chances for survival, especially for pregnancies less than 30 weeks of gestation. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, ПЕРИУРЕТЕРАЛНА ЕНДОМЕТРИОЗА – ПРИКАЗ НА СЛУЧАЈ(SHMSHM - AAMD, 2022-09-01); ; ; ; Целта на овој труд е да се прикаже редок случај на периуретерална ендометриоза кај возрасен пациент и да се нагласи важноста на сомнителната уринарна ендометриоза и важната улога на компјутер на мала карлица во поставувањето на точна дијагноза на оваа ретка болест. Презентираме редок случај на периуретерална ендометриоза со симптоми кои првенствено произлегуваат од ендометриоза на јајниците. Дијагнозата на периуретерална ендометриоза беше поставена врз основа на компјутеризирана томографија на малата карлица и абдоменот. Клучни зборови: ендометриоза, компјутер на мала карлица, периуретерална ендометриоза. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Reproductive Outcome after Hysteroscopic Metroplasty in Patients with Infertility and Recurrent Pregnancy Loss(ID Design 2012/Scientific Foundation SPIROSKI, 2014-03-15); Introduction: Reproductive outcome can be negatively affected in patients with congenital uterine anomalies (CUA), increasing the number of unsuccessful pregnancies and obstetric complications. Compared with the population with normally formed uterus, patients with CUA have higher abortion rate, higher fetal loss rate and decreased live birth rate. Hysteroscopic metroplasty (HM) is a standard, safe and minimally invasive method for the treatment of correctible types of congenital uterine anomalies.Aim: The aim of the study was to analyze the reproductive outcome in group of patients with infertility and recurrent pregnancy loss and present CUA, before and after hysteroscopic metroplasty.Material and Methods: We analyzed 67 patients to whom 78 interventions hysteroscopic metroplasty were performed at the University Clinic of Obstetrics and Gynecology in Skopje during a two year period, between 01.01.2010 and 31.12.2011. Their reproductive outcome was monitored during a two-year period and the same group served as a control group, taking into account their previous reproductive history. Statistical analysis was performed using Chi-square test and p < 0.05 was considered to be statistically significant.Results: Most common CUA were types 5b and 6 represented by 88 %. In a follow up period of two years, 33 of the patients become pregnant. There was a statistically significant decrease of abortion rate from 92% to 21.2%, as well as an increase in the term delivery rate from 0% to 69.7%.Conclusion: Treatment with hysteroscopic metroplasty is significantly improving the reproductive outcome in patients with CUA and previous fetal loss. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Incidence and Prevalence of Vaginal Infections in Women of Reproductive Age in North Macedonia(Macedonian Academy of Sciences and Arts/Walter de Gruyter GmbH, 2023-07-01); In the available literature on this subject there are many studies which describe the effects of sexually transmitted infections on pregnancy and fertility of women. Because of the frequency of the infections with the atypical bacteria of the Ureaplasma Spp., Mycoplasma Spp., Chlamydia Trachomatis, as well as HPV infections in women of reproductive age, it is easy to underestimate their importance when establishing the basis of the genital health of women of reproductive age. In this prospective analysis, conducted from 2014 to 2018 in the laboratory for HPV and Molecular diagnostics at the University Clinic of Gynaecology and Obstetrics in Skopje, North Macedonia, we analysed the results of 10,387 patients of all ages, of which 973 patients were of reproductive age. A Panel analysis was also conducted (including the above-mentioned pathogens). An HPV analysis was also conducted on 643 patients in this group. Within the group of 643 patients, there was a positive result for HPV in 26.7% of them, while in 40.9% there was a positive result for one or more pathogens on the Panel analysis of bacterial pathogens. The statistical analysis of the results showed that the most frequent of all bacterial pathogens within the Macedonian population of women of reproductive age is Ureaplasma Spp, with an incidence of 33%, followed by Mycoplasma Spp., with 7.8%, while Chlamydia Trachomatis was present in 6.4% of the cases. We should highlight that a co-infection with HPV was present in 18.5% of all the patients where there was analysis of both diagnostic procedures. The analysis of the results in the patients co-infected with HPV and at least one bacterial pathogen on the Panel Analysis, showed a very high statistical correlation (p<001). - Some of the metrics are blocked by yourconsent settings
Item type:Publication, HYDROSALPINX AND DISTRIBUTION OF PREGNANCIES AMONG LAPAROSCOPICALLY TREATED PАTIENTS(Македонско лекарско друштво = Macedonian Medical Association, 2020); ; Introduction. Hydrosalpinx is a common medical condition encountered among female population with infertility issues. One or both fallopian tubes can be filled with a substantial amount of fluid, making them dilated and dysfunctional, usually as a result of an injury or infection. Damages of different degrees can be seen on the mucosal lining, which compromise the processes of normal fertilization and zygote passage. Methods. We retrospectively analyzed clinical records from a period of five years (2013-2017), selecting pa- tients diagnosed as having unilateral or bilateral hydrosalpinx. Clinical files were divided by years and according to the treatment protocol used. Our scope of interest was focused on patients who were treated surgically, with different types of laparoscopic interventions. A total of 74 patients met our criteria for selection. Results. Two groups were related to conservative la- paroscopic approaches and one to complete radical surgical treatment, unilateral or bilateral salpingectomy. Patients in the first group, 9(16.36%), were treated with a laparoscopically-guided creation of salpingostomy. The second group comprised patients treated only with bi- lateral chromopertubation and consisted of 17 (30.91%) patients. The third, and the most numerous group com- prised 29(52.7%) patients treated with salpingectomy. Bilateral salpingectomy was performed in 9(31.03%) and unilateral in 20(68.97%) patients, showing that majority of patients were treated with unilateral salpingectomy, after intraoperative evaluation of tubal patency of the contralateral uterine tube. A total number of 30 patients (54.5%) had successful pregnancies, which ended up with a desired outcome, healthy live birth. Procedures for artificial reproduction and successful pregnancies achieved with IVF were recorded in 11(36.67%) patients and in the remaining 19(63.33%) patients pregnancies were achieved via spontaneous conception. Conclusion. Hydrosalpinx management is mainly influenced by the local tubal changes evaluated laparoscopically and can be surgically treated, either conservative or radical. Conservative approaches lead to fair chances of spontaneous conception and successful pregnancies. An integrated management of hydrosalpinx with bilateral salpingectomy and postsurgical usage of artificial reproduction techniques also leads to a substantial cumulative pregnancy rate. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Heterotopic pregnancy(JCMICR, 2022-05); ; Heterotopic pregnancy is defined as a condition when intrauterine and extra uterine pregnancy occur simultaneously. It is a life-threatening condition that requires immediate and accurate diagnostics and treatment. It is difficult to diagnose and easily missed. The incidence in the general population is estimated to be 1 in 30,000. With the advent of Assisted Reproduction Techniques (ART) and ovulation induction, the overall incidence of heterotopic pregnancy has risen to approximately 1 in 3,900 pregnancies. Other risk factors include a history of pelvic inflammatory disease (PID), tubal damage, pelvic surgery, uterine Mullerian abnormalities, and prior tubal surgery. Heterotopic pregnancy is a potentially fatal condition, rarely occurring in natural conception cycles. Most commonly, heterotopic pregnancy is diagnosed at the time of rupture when surgical management is required. We present a case of a 30-year-old secondi gravida with history of one spontaneous abortion and pelvic inflammatory disease, who conceived spontaneously and at her fifth week of amenorrhea, was presented to the emergency department with acute pain in lower abdomen, moderate vaginal bleeding and weakness. Laboratory tests and transvaginal ultrasonography revealed the diagnosis of heterotopic pregnancy. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diagnostic performance of human epididymis protein 4 compared to a combination of biophysical and biochemical markers to differentiate ovarian endometriosis from epthelial ovarian cancer in premenopausal women d biochemical markers to differentiate ovarian endometriosis from epithelial ovarian cancer in premenopausal women(Japan Society of Obstetrics and Gynecology, 2017-12); Marko StanojevicAim: This study is a comparison of human epididymis protein 4 (HE4) with cancer antigen 125 (CA125), using the Risk of Ovarian Malignancy Algorithm (ROMA), Copenhagen Index (CPH-I), Risk of Malignancy Index (RMI) and Morphology Index (MI) to differentiate ovarian endometriosis from epithelial ovarian cancer (EOC) in premenopausal women. Methods: The study was performed at the University Clinic of Obstetrics and Gynecology in Skopje. One hundred and sixty-four premenopausal patients were divided into three study groups, including ovarian endometriosis (37), other benign pelvic masses (57) and EOCs (11), and a control group (59). After ultrasonography, all subjects underwent blood sampling. Surgery and histological verification was performed. Pelvic masses were classified based on histological findings. Mann–Whitney, receiver operating characteristicarea under the curve (AUC), sensitivity, specificity and Kruskal–Wallis tests were used for statistical analysis. The level of significance α was set at 5%. Results: For each of the tested markers, sensitivity, specificity and accuracy to distinguish ovarian endometriosis from EOC were as follows: HE4 (81.82%, 100%, 95.83%); CA125 (81.82%, 48.65%, 56.25%); ROMA (90.91%, 83.78%, 85.42%); CPH-I (81.82%, 97.30%, 93.75%); RMI (90.91%, 35.14%, 47.92%); and MI (100%, 75.68%, 81.25%), respectively. The AUC for ovarian endometriosis compared to EOC for tested markers was as follows: HE4 (AUC = 0.934), CA125 (AUC = 0.821), ROMA (AUC = 0.929), CPH-I (AUC = 0.924) and RMI (AUC = 0.880), respectively. Conclusion: HE4 and CPH-I perform best to discriminate ovarian endometriosis from EOC in premenopausal women. MI has maximal sensitivity to detect EOC. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Acute appendicitis in the third trimester of a pregnancy finished with spontaneous vaginal delivery(Asclepius, 2018); ; ; Acute appendicitis is the most common surgical problem occurring during pregnancy. Its incidence is more common in the second trimester and is confirmed in 1/1000 pregnancies. Clinical manifestations of acute appendicitis in pregnant patients are generally very similar to non- pregnant patients. We present, here, the case of a 29-year-old pregnant patient at 35+4 weeks of gestation with the signs of acute appendicitis. The patient underwent a successful open appendectomy of her perforated appendix, without performing a cesarean section (CS) at the same time. 5 weeks postoperatively, at term, labor was induced with vaginal prostaglandins and the patient delivered a healthy female baby without any complications. Immediate diagnosis of acute appendicitis during pregnancy is recommended and management with the suitable surgical intervention should not be delayed for >24 h as it increases the risk of perforation with its subsequent critical complications. The treatment of acute appendicitis is always surgical, with an appendectomy and perioperative broad-spectrum antibiotics. Except in cases of high maternal and fetal mortality, a CS should not be done simultaneously with the appendectomy in cases of a perforated appendix with diffuse peritonitis, due to the very high risk of dehiscence of the uterus. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, SUCCESSFULLY TREATED INFERTILITY IN A PATIENT WITH TURNER SYNDROME WITH IN VITRO FERTILIZATION WITH DONATED EGG – A CASE REPORT(Македонско лекарско друштво = Macedonian Medical Association, 2020); ; ; Buklievska AdrijanaWe present a case of a 34-year-old woman, diagnosed with Turner syndrome at the age of 18 because of short stature and irregular menstrual cycle. After the diagnosis had been established, she started with hormonal therapy for regulation of the menstrual cycle. When she got married at the age of 32 she wanted to conceive, but it was not successful and after one year she decided to make in vitro fertilization with a donated egg. It was successful in the first attempt. Her high-risk pregnancy was followed up by her gynecologist and obstetrician in atertiary level institution. The pregnancy was normal, without complications. During the pregnancy examinations at the University Clinic for Cardiology in Skopje were made and cardiovascular diseases were excluded. In 39 week of gestation an elective Caesarean section was made at the University Clinic for Gynecology and Obstetrics in Skopje, R. N. Macedonia. On 28th of February 2019 she delivered a healthy baby boy with birth weight of 2950 gr and birth length of 48 cm, with Apgar scores 8 and 9 at 1 and 5 min, respectively. No severe complications occurred during the postpartum period. By application of new assisted reproductive techniques such as in vitro fertilization with a donated egg, women with Turner syndrome and infertility can resolve their problem and fulfill their wish to have a baby. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Macrohematuria in SARS-COV-2 pregnant patient(Македонско лекарско друштво = Macedonian medical association, 2021); ; ; Bejta, AlbinaCovid-19 is a new virus and very little research has been done regarding it. Target organs of SARS-CoV-2 are not only the lungs and the heart but other organs as well. There has been a huge focus on the effect this novel virus has on the kidneys. This is proven by the presence of proteinuria, hematuria and acute kidney injury (AKI). This has been specifically noted in pregnant women, who are a target group for a more complex COVID19 disease than in the nonpregnant ones. We have reported a case of a COVID19 positive patient with a gemellar pregnancy complicated with macrohematuria because of transitory glomerular damage due to the virus infection. The patient delivered two healthy COVID19 negative newborns, while she continued treatment in the Clinic of Infectology. Pregnant women, without any previous kidney pathology are prone to kidney damage as a result of SARS-CoV-2 infection, and should be closely monitored for the development of AKI in order to prevent it. Keywords: SARS-CoV-2, macrohematuria, acidum uricum, kidney
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