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    Epidemiological Characteristics of Major Depression of Hospitalized Patients in Psychiatric Hospital “Demir Hisar” – Demir Hisar for a Five Year Period from 2013 to 2017
    (Scientific foundation Spiroski, 2020-05-10)
    Iliev, Biljana
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    <jats:p>BACKGROUND: Severe depression is a mental disorder with a wide range of changes in psychic functions, primarily of affectivity, and is manifested by dysphoric mood and reductive changes in cognitive, conative, and other psychic dynamics, with the presence of psychosomatic complaints and suicidal thoughts. There is always a triad of symptoms: Alteration of affectivity, anhedonia, and low energy with fatigue, but in her clinical picture, there are other symptoms, such as feeling guilty and helpless, obsessed with “black thoughts” with loss of confidence in themselves, with hopelessness, loss of appetite, and weight loss with present insomnia or hypersomnia, and more frequent thinking about death due to the feeling of worthlessness of life. This mental illness covers a vast area of the affective life of a human with a broad spectrum classified by ICD - 10- F 32, F 32.2, and F 32.3. AIM: The main goal is to determine the total number of patients with the major depression treated at “Demir Hisar” Psychiatric Hospital for a period of 5 years, retrospectively in 2013 until 2017 and to determine the impact of socio-demographic variables as risk factors and predictors. METHODS: The study is retrospective, and the necessary parameters for achieving the goals of the research are provided by analyzing the medical histories of all hospitalized patients treated in psychiatric hospitals Demir Hisar in the period from 2013 to 2017. Incidence rates and indexes of the dynamics of hospitalized patients with major depression were determined. RESULTS: About 61.8% of the patients are men and 38.2% women. Patients with no education and elementary school were 64.5% versus patients with high school and university 35.5% and are significantly underpowered. Regarding the employment status, 38.2% of patients are unemployed, and 61.8% of patients are employed. According to the cross-sectional study, 64.7% of men without education have severe depression and live in the city, and 53.3% of women with secondary education live in urban areas (city), meaning rural residence is associated with a reduced rate of severe depression. CONCLUSION: We can conclude that socio-demographic characteristics – age, gender, marital status, level of education, employment/unemployment status, and place of residence are related to the severity of depression.</jats:p>
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    Influence of Primary Packaging on Attitudes towards Smoking in RN Macedonia
    (BiomedGrid LLC, 2019-12-04)
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    Andrej Bonevski
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    Screening for hepatitis C among injecting drug users in Psychiatric Hospital Skopje
    (Medical Faculty, Ss Cyril and Methodius University Skopje, R. Macedonia, 2017)
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    Epidemiological Characteristics of Great Depression Diseases of Hospitalized Patients in Psychiatric Hospital “Negorci” for a Five-Year Period From 2013 to 2017
    (Scientific Foundation SPIROSKI, 2020-05-20)
    Biljana, Iliev
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    <jats:p>BACKGROUND: Severe depression beside the pathological mood also denotes the cognitive, perceptual, and motor activities that are psychopathologically related to the scope of all psychic dynamics, which means cognitive, conative, and emotional. This mental illness covers a large area of the affective life of a man with a wide range of severe depression classified by ICD-10 – F32, F32.2, and F32.3 . With retrospective approach to research from medical history collects data on biological and social factors that have a positive or negative effect on the onset and course of severe depression. AIM: The research aims to determine the total number of patients with severe depression treated in hospital conditions in the Psychiatric Hospital “Negorci” – Negorci for a period of 5 years from 2013 to 2017 to get a clear picture of the factors and specific predictors that lead to the development of severe depression. METHODS: Within the research methods, all the parameters contained are calculated so that it can be concluded that the predictors influence and differ from other stakeholders responsible for etiopathogenesis, although they have a mutual influence. RESULTS: According to the current study, patients with severe depression were found to have an increased frequency between 45 and 62 years. The mean age of the respondents was 52.14 years. According to the level of education, the majority (49%) of the patients have completed primary education and the least with higher education, i.e., only 2 (3.1%). CONCLUSION: From the obtained data, it was obtained the scope of the influence of sociodemographic data on the occurrence of severe depression and sequelae of the disease.</jats:p>
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    RELIGION AND SPIRITUALITY-PROTECTIVE FACTOR IN SUICIDE ATTEMPTS IN PEOPLE WITH DEPRESSION
    (Medicinska naklada, 2019)
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    Spirituality as a dimension of quality of life and well-being has recently begun to be more valued within the treatment approaches to mental health. A range of studies have also looked at spirituality or affiliation to spiritual or religious groups in relation to suicide and suicide attempts. Nisbet et al. (2000) reported that the suicide rate is four times lower in people who attend religious activities. In this study of 31 patients with depression, it is found that those who are attending religious activities, or those who have reported having a spiritual faith, were significantly less likely to have suicidal attempts. Results suggest that religious attendance and spiritual faith is associated with decreased suicide attempts. These findings that the depressive patients who have no religious affiliation, who are not attending religious activities or having spiritual faith, have higher rates of suicide attempts gives an association that religion and spirituality may act as a protective factor against suicide attempts, because of the religious social mores or ‘rules’ which prevent behaviors as suicide attempts.
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    Psychiatrists' treatment preferences for generalized anxiety disorder
    (Wiley, 2018)
    Latas, Milan
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    Trajković, Goran
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    Vučinić Latas, Dušanka
    The objective of this study is to ascertain psychiatrists' treatment preferences for generalized anxiety disorder (GAD) and compare them to the same psychiatrists' treatment preferences in the hypothetical scenario that treatment is to be administered to themselves as patients.
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    Correlation between methadone dosage, cortisol plasma level and depression in methadone maintained patients
    (AU-CNS, 2015-12)
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    Background. Opioids can affect neuroendocrine functions, with the consequence that various endocrine abnormalities, including the increased level of cortisol that can result from depression, may be acceptable in patients who use opioids. Aim of this study is to examine the correlation between methadone dosage, cortisol plasma level and depression in methadone-maintained patients. Methods. This is an analytical, cross-sectional study that included 45 patients, who were divided into two groups. The first group consisted of 10 patients (4 females and 6 males), whose doses ranged between 10 and 55 mg. The second group consisted of 35 patients (5 females and 30 males), whose doses ranged between 65 and 120 mg. To discover demographic characteristics we used medical records, to determine cortisol plasma level we relied on the Chemiluminescence Immunoassay (CLIA) method, and to determine depression we made use of the Beck depression inventory (BDI). The results were statistically analysed using a combination of descriptive methods – the t-test for independent samples, the χ² test, the Mann-Whitney U test and the Pearson coefficient of linear correlation. Results. Theresults obtained show statistically significant differences between the two groups in terms of their BDI scores, with higher scores indicating patients who were taking higher doses. There is a statistically significant correlation between cortisol plasma level and depression, but not between methadone maintenance dose and cortisol plasma level, even if a high proportion of patients in the group taking higher doses showed a higher cortisol plasma level. Conclusions. In methadonemaintained patients the methadone dose is not statistically correlated with cortisol plasma level, but some other factors in the group taking higher methadone doses tend to determine higher BDI scores.
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    HOPE AND HOPELESSNESS IN PSYCHOTHERAPY: THE ROLE OF HOPE IN BUFFERING THE IMPACT OF HOPELESSNESS
    (Medicinska naklada, 2018)
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    People react differently to stressors in life, with some individuals deliberately putting an end to their lives in the face of adversity and others endeavoring to proceed. The notion that hope and help may buffer individuals against suicidal ideation is built on empirical findings in the literature suggesting that hope and help buffers individuals against psychopathology and that hope and help contributes to better outcomes in a variety of negative situations. It is not clear whether it is the hope and help construct or hopelessness and helplessness construct that should be targeted in psychotherapy, in reducing suicidal ideation. Underlying this problem is a more fundamental question concerning whether hope and help are simply the inverse of hopelessness/helplessness, which is a controversial topic to a number of researchers, psychologists and psychiatrists in the field. If we see the genesis of helplessness and hopelessness, helplessness reflects a loss of ego autonomy with a feeling of deprivation resulting from the loss of gratification which is desired from an other-than-self object, while hopelessness, on the other hand, is a loss of autonomy with a feeling of despair coming from the individual’s awareness of his own inability to provide himself with gratification. Both hopelessness and helplessness are connected to the loss of ego autonomy and lack of help from another person. Hopelessness/helplessness dyad (and the opposites hope/help) encompasses other concepts used in psychotherapy: conscious, unconscious, deprivation, depression, despair, gratification, self, other, relational patterns, autonomy... This study goes beyond the examination of a direct association between hope, help and suicidal ideation to investigate hope and help as a resilience factor which buffers the strength of the association between hopelessness, helplessness and suicidal ideation.
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    TRAUMA AND ANXIETY DISORDERS THROUGHOUT LIFESPAN: FEAR AND ANXIETY FROM NORMALITY TO DISORDER
    (Medicinska naklada, 2018)
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    Anxiety disorders are among the most common mental disorders. Anxiety disorders and neurotic fear cause significant disruption of the psychosocial functioning of the individual. In generalized anxiety disorder, neurotic fear appears in the form of fears, expectations, tension, with nothing specifically uncomprehendingly crying anticipation, worry, poor concentration, psychic and physical fatigue, irritability, restlessness, insomnia, sense of near accident etc. Traumatic events in the life of the individual are often referred to as potential relevant factors in the occurrence of psychological disorders. Exposure to long-lasting traumatic experiences in childhood leads to the prolongation and fixation of the emotional state of fear and sadness and the emphasized use of certain defense mechanisms that contribute to the structuring of specific clinical images of anxiety states