Ве молиме користете го овој идентификатор да го цитирате или поврзете овој запис:
http://hdl.handle.net/20.500.12188/30628
Наслов: | Effect of intra-arterial Nimodipine on subarachnoid hemorrhage injured brain | Authors: | Bushinoska, Jasna CHaparoski, Aleksandar Dodevski, Ace Bushinoska Ivanova, Gabriela Ognjenovic, Ljubomir Asani, Elmedina Zafirova, Dina Vesova, Marija |
Keywords: | vasospasam SAH Nimodipine intraarterial Endovascular treatment |
Issue Date: | 31-авг-2022 | Publisher: | Macedonian Association of Anatomists and Morphologists | Journal: | Journal of Morphological Sciences | Abstract: | Subarachnoid hemorrhage is a pathological condition of the brain, caused by rupture of intracerebral aneurism or arteriovenous malformation, with high morbidity and mortality rate. SAH may conceive permanent brain damage with persistent disability. Vasospasm isthe most characteristic pathological state of the vasculature, whose development coincides with onset of bleeding with asymptomatic presentation. The critical extend as a risk factor presentswith symptom presentation and indication of brain damage development. Early vasospasm treatment is a priority in prevention of brain ischemia and disability. Existing methods of vasospasm treatment are conservative, endovascular and combined, with simultaneous intraarterial vasodilator application.The aimof this study wasto determine whether intraarterial application of Calcium-blocker Nimodipine will generate immediate vasodilation, facilitating endovascular aneurism treatment, resulting in longterm resolution of the condition.Fifteen patients with SAH receivedendovascular treatment in the first 48 hours of hemorrhage onset, with consequent intraarterialNimodipine application if vasospasm was detected. All patients had ruptured aneurism of anterior circulation. Vessel diameter was measured before and after Nimodipine application. The occurrence and degree of vasodilation, as a difference between both diameters,were considered a confirmation of drug effectiveness.Complete spasm relief occurred in 10patients, residual vasospasm persisted in 4 patients, no VS relief occurred in 1 patient.IntraarterialNimodipine application during endovascular brain aneurism treatment effectively relievesvasospasm. Early coiling reduces complication risks and development of postischemic brain damage. | URI: | http://hdl.handle.net/20.500.12188/30628 | DOI: | 10.55302/JMS2252135b |
Appears in Collections: | Faculty of Medicine: Journal Articles |
Files in This Item:
File | Опис | Size | Format | |
---|---|---|---|---|
394-1-1905-2-10-20220901.pdf | 586.62 kB | Adobe PDF | View/Open |
Page view(s)
41
checked on 22.9.2024
Download(s)
9
checked on 22.9.2024
Google ScholarTM
Проверете
Altmetric
Записите во DSpace се заштитени со авторски права, со сите права задржани, освен ако не е поинаку наведено.