Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12188/14997
Title: Effect of prebiotic content on functional and physicochemical properties of Lactobacillus casei loaded chitosan-Ca-alginate microparticles
Authors: Petreska Ivanovska, Tanja
Mladenovska, Kristina 
Kavrakovski, Zoran 
Bogdanovska, Liljana 
Grozdanov, Anita 
Popovski, Emil 
Petrushevska-Tozi, Lidija
Issue Date: Oct-2012
Publisher: Macedonian Pharmaceutical Association
Journal: Macedonian Pharmaceutical Bulletin
Abstract: <jats:p>This study aims to evaluate the influence of different concentrations of fructooligosaccharide (FOS) as prebiotic on functional and physicochemical properties of Lactobacillus casei loaded chitosan-Ca-alginate microparticles prepared by spray-drying method, after preparation and 6-month storage at 4 °C. Prebiotic compound positively influenced the viability of L. casei during preparation of the microparticles and in storage conditions, while no significant difference of the probiotic viability was observed when different concentrations of FOS in a range of 1.5 - 5% w/w were applied. Having in regard that non-significant improvement in the functional and physicochemical properties of the microparticles with increased content of the FOS was observed, the concentration of 1.5% w/w was recommended as an optimal for preparation of synbiotic loaded microparticles.</jats:p>
URI: http://hdl.handle.net/20.500.12188/14997
DOI: 10.33320/maced.pharm.bull.2012.58.006
Appears in Collections:Faculty of Natural Sciences and Mathematics: Journal Articles

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